Reviewed
Homo Sapiens (Human) [TaxID: 9606]; Pteropus Alecto (Black Flying Fox) [TaxID: 9402]; Pteropus Conspicillatus (Spectacled Flying Fox) [TaxID: 328804]; Pteropus Poliocephalus (Grey-headed Flying Fox) [TaxID: 9403]; Pteropus Scapulatus (Little Red Flying Fox) [TaxID: 94117]; Saccolaimus [TaxID: 446909]
N[Gene ID: 926728 ]
Nucleoprotein (NP) (Nucleocapsid protein) (Protein N)
Australian Bat Lyssavirus (isolate Bat/AUS/1996) (ABLV)
Viruses> SsRNA Viruses> SsRNA Negative-strand Viruses> Mononegavirales> Rhabdoviridae> Lyssavirus> Australian Bat Lyssavirus> Australian Bat Lyssavirus (isolate Bat/AUS/1996) (ABLV)
Various pathway(s) in which protein is involved
Not Available
MESDKIAFKINNQLVSVKPEVIVDQYEYKYPAIKDQRKPSITLGKAPDLNKAYKSILSGMNAAKLDPDDVCSYLAAAMELFEGICPEDWTSYGILIARKG
DKITPATLVDIRRTDIQGSWALAGGQDFTRDPTIAEHASLVGLLLSLYRLSKISGQNTGNYKTNIADRIEQIFETAPFAKIVEHHTLMTTHKMCANWSTI
PNFRFLAGTYDMFFSRVEHLYSAIRVGTVVTAYEDCSGLVSFTGFIKQINLTAREAILYFFHKNFEEEIRRMFEPGQETAVPHSYFIHFRSLGLSGKSPY
SSNAVGHVFNLIHFVGCYMGQIRSLNATVISTCAPHEMSVLGGYLGEEFFGKGTFERRFFRDEKELQDYEAAEAMKIDLALADDGTVNSYDEDYLSGETR
SPEAVYTRIMMNGGRLKKSHIRRYISVSSNHQSRPNSFAEFLNKTYSSDS
DKITPATLVDIRRTDIQGSWALAGGQDFTRDPTIAEHASLVGLLLSLYRLSKISGQNTGNYKTNIADRIEQIFETAPFAKIVEHHTLMTTHKMCANWSTI
PNFRFLAGTYDMFFSRVEHLYSAIRVGTVVTAYEDCSGLVSFTGFIKQINLTAREAILYFFHKNFEEEIRRMFEPGQETAVPHSYFIHFRSLGLSGKSPY
SSNAVGHVFNLIHFVGCYMGQIRSLNATVISTCAPHEMSVLGGYLGEEFFGKGTFERRFFRDEKELQDYEAAEAMKIDLALADDGTVNSYDEDYLSGETR
SPEAVYTRIMMNGGRLKKSHIRRYISVSSNHQSRPNSFAEFLNKTYSSDS
450
Not Available
Not Available
01-05-2000
Inferred from homology
| Amino Acid | Count | % Frequency | Amino Acid | Count | % Frequency |
|---|---|---|---|---|---|
| Alanine (A) | Leucine (L) | ||||
| Arginine (R) | Lysine (K) | ||||
| Asparagine (N) | Methionine (M) | ||||
| Aspartic Acid (D) | Phenylalanine (F) | ||||
| Cysteine (C) | Proline (P) | ||||
| Glutamine (Q) | Serine (S) | ||||
| Glutamic Acid (E) | Threonine (T) | ||||
| Glycine (G) | Tryptophan (W) | ||||
| Histidine (H) | Tyrosine (Y) | ||||
| Isoleucine (I) | Valine (V) |
| % Number of Residues in Helices | % Number of Residues in Strands | % Number of Residues in Coils |
|---|---|---|
Encapsidates the genome in a ratio of one protein N per nine ribonucleotides, protecting it from nucleases. If expressed without protein P it binds non-specifically RNA and therefore can bind it's own mRNA. Interaction with protein P abolishes any non-specific RNA binding, and prevents phosphorylation. The soluble N-P complex encapsidates specifically the genomic RNA, with protein N protecting the genome like a pearl necklace. The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for viral transcription and replication. Protein N binds protein P in the NC through a different interaction, and can be phosphorylated. Subsequent viral replication is dependent on intracellular concentration of newly synthesized protein N. During replication, encapsidation by protein N is coupled to RNA synthesis and all replicative products are resistant to nucleases (By similarity).
Not Available
Virion. Host cytoplasm .
Not Available
Not Available
Predicted/Modelled
Not Available
Not Available
Protein couldn't be modeled using I-Tasser and Raptor X because of length constraints of the software.
Not Available
- Million Molecules
Best 20 Hit molecules
Not Available