Reviewed
Homo Sapiens (Human) [TaxID: 9606]
MCP U57[Gene ID: 1497059 ]
Major capsid protein (MCP)
Human Herpesvirus 6B (strain Z29) (HHV-6 Variant B) (Human B Lymphotropic Virus)
Viruses> DsDNA Viruses> No RNA Stage> Herpesvirales> Herpesviridae> Betaherpesvirinae> Roseolovirus> Human Herpesvirus 6B (HHV-6 Variant B) (Human B Lymphotropic Virus)> Human Herpesvirus 6B (strain Z29) (HHV-6 Variant B) (Human B Lymphotropic Virus)
Various pathway(s) in which protein is involved
Not Available
MENWQATEILPKIEAPLNIFNDIKTYTAEQLFDNLRIYFGDDPSRYNISFEALLGIYCNKIEWINFFTTPIAVAANVIRFNDVSRMTLGKVLFFIQLPRV
ATGNDVTAPKETTIMVAKHSEKHPINISFDLSAACLEHLENTFKNTVIDQILNINALHTVLRSLKNSADSLERGLIHAFMQTLLRKSPPQFIVLTMNENK
VHNKQALSRVQRSNMFQSLKNRLLTSLFFLNRNNNSSYIYRILNDMMESVTESILNDTNNYTSKENIPLDGVLLGPIGSIQKLTNILSQYISTQVVSAPI
SYGHFIMGKENAVTAIAYRAIMADFTQFTVNAGTEQQDTNNKSEIFDKSRAYADLKLNTLKLGDKLVAFDHLHKVYKNTDVNDPLEQSLQLTFFFPLGIY
IPTETGFSTMETRVKLNDTMENNLPTSVFFHNKDQVVQRIDFADILPSVCHPIVHDSTIVERLMKNEPLPTGHRFSQLCQLKITRENPTRILQTLYNLYE
SRQEVPKNTNVLKNELNVEDFYKPDNPTLPTERHPFFDLTYIQKNRATEVLCTPRIMIGNMPLPLAPISFHEARTNQMLEHAKTNSHNYDFTLKIVTESL
TSGSYPELAYVIEILVHGNKHAFMILKQVISQCISYWFNMKHILLFCNSFEMIMLISNHMGDELIPGAAFAHYRNLVSLIRLVKRTISISNINEQLCGEP
LVNFANALFDGRLFCPFVHTMPRNDTNAKITADDTPLTQNTVRVRNYEISDVQRMNLIDSSVVFTDNDRPSNENTILSKIFYFCVLPALSNNKACGAGVN
VKELVLDLFYTEPFICPDDCFQENPISSDVLMSLIREAMGPGYTVANTSSIAKQLFKSLIYINENTKILEVEVSLDPAQRHGNSVHFQSLQHILYNGLCL
ISPITTLRRYYQPIPFHRFFSDPGICGTMNADIQVFLNTFPHYQRNDGGFPLPPPLALEFYNWQRTPFSVYSAFCPNSLLSIMTLAAMHSKLSPVAIAIQ
SKSKIHPGFAATLVRTDNFDVECLLYSSRAATSIILDDPTVTAEAKDIVTTYNFTQHLSFVDMGLGFSSTTATANLKRIKSDMGSKIQNLFSAFPIHAFT
NTDINTWIRHHVGIEKPNPSEGEALNIITFGGINKNPPSILLHGQQAICEVILTPVTTNINFFKLPHNPRGRESCMMGTDPHNEEAARKALYDHTQTDSD
TFAATTNPWASLPGSLGDILYNTAHREQLCYNPKTYSPNAQFFTESDILKTNKMMYKVINEYCMKSNSCLNSDSEIQYSCSEGTDSFVSRPCQFLQNALP
LHCSSNQALLESRSKTGNTQISETHYCNYAIGETIPLQLIIESSI
ATGNDVTAPKETTIMVAKHSEKHPINISFDLSAACLEHLENTFKNTVIDQILNINALHTVLRSLKNSADSLERGLIHAFMQTLLRKSPPQFIVLTMNENK
VHNKQALSRVQRSNMFQSLKNRLLTSLFFLNRNNNSSYIYRILNDMMESVTESILNDTNNYTSKENIPLDGVLLGPIGSIQKLTNILSQYISTQVVSAPI
SYGHFIMGKENAVTAIAYRAIMADFTQFTVNAGTEQQDTNNKSEIFDKSRAYADLKLNTLKLGDKLVAFDHLHKVYKNTDVNDPLEQSLQLTFFFPLGIY
IPTETGFSTMETRVKLNDTMENNLPTSVFFHNKDQVVQRIDFADILPSVCHPIVHDSTIVERLMKNEPLPTGHRFSQLCQLKITRENPTRILQTLYNLYE
SRQEVPKNTNVLKNELNVEDFYKPDNPTLPTERHPFFDLTYIQKNRATEVLCTPRIMIGNMPLPLAPISFHEARTNQMLEHAKTNSHNYDFTLKIVTESL
TSGSYPELAYVIEILVHGNKHAFMILKQVISQCISYWFNMKHILLFCNSFEMIMLISNHMGDELIPGAAFAHYRNLVSLIRLVKRTISISNINEQLCGEP
LVNFANALFDGRLFCPFVHTMPRNDTNAKITADDTPLTQNTVRVRNYEISDVQRMNLIDSSVVFTDNDRPSNENTILSKIFYFCVLPALSNNKACGAGVN
VKELVLDLFYTEPFICPDDCFQENPISSDVLMSLIREAMGPGYTVANTSSIAKQLFKSLIYINENTKILEVEVSLDPAQRHGNSVHFQSLQHILYNGLCL
ISPITTLRRYYQPIPFHRFFSDPGICGTMNADIQVFLNTFPHYQRNDGGFPLPPPLALEFYNWQRTPFSVYSAFCPNSLLSIMTLAAMHSKLSPVAIAIQ
SKSKIHPGFAATLVRTDNFDVECLLYSSRAATSIILDDPTVTAEAKDIVTTYNFTQHLSFVDMGLGFSSTTATANLKRIKSDMGSKIQNLFSAFPIHAFT
NTDINTWIRHHVGIEKPNPSEGEALNIITFGGINKNPPSILLHGQQAICEVILTPVTTNINFFKLPHNPRGRESCMMGTDPHNEEAARKALYDHTQTDSD
TFAATTNPWASLPGSLGDILYNTAHREQLCYNPKTYSPNAQFFTESDILKTNKMMYKVINEYCMKSNSCLNSDSEIQYSCSEGTDSFVSRPCQFLQNALP
LHCSSNQALLESRSKTGNTQISETHYCNYAIGETIPLQLIIESSI
1345
Not Available
Not Available
01-05-2000
Inferred from homology
| Amino Acid | Count | % Frequency | Amino Acid | Count | % Frequency |
|---|---|---|---|---|---|
| Alanine (A) | Leucine (L) | ||||
| Arginine (R) | Lysine (K) | ||||
| Asparagine (N) | Methionine (M) | ||||
| Aspartic Acid (D) | Phenylalanine (F) | ||||
| Cysteine (C) | Proline (P) | ||||
| Glutamine (Q) | Serine (S) | ||||
| Glutamic Acid (E) | Threonine (T) | ||||
| Glycine (G) | Tryptophan (W) | ||||
| Histidine (H) | Tyrosine (Y) | ||||
| Isoleucine (I) | Valine (V) |
| % Number of Residues in Helices | % Number of Residues in Strands | % Number of Residues in Coils |
|---|---|---|
Self-assembles to form an icosahedral capsid with a T=16 symmetry, about 200 nm in diameter, and consisting of 150 hexons and 12 pentons (total of 162 capsomers). Hexons form the edges and faces of the capsid and are each composed of six MCP molecules. In contrast, one penton is found at each of the 12 vertices. Eleven of the pentons are MCP pentamers, while the last vertex is occupied by the portal complex. The capsid is surrounded by a layer of proteinaceous material designated the tegument which, in turn, is enclosed in an envelope of host cell-derived lipids containing virus-encoded glycoproteins.
Not Available
Virion . Host nucleus .
Not Available
Not Available
Predicted/Modelled
Not Available
Not Available
Protein couldn't be modeled using I-Tasser and Raptor X because of length constraints of the software.
Not Available
- Million Molecules
Best 20 Hit molecules
Not Available