Reviewed
Erythrocebus Patas (Red Guenon) (Cercopithecus Patas) [TaxID: 9538]; Homo Sapiens (Human) [TaxID: 9606]; Macaca (macaques) [TaxID: 9539]; Papio Hamadryas (Hamadryas Baboon) [TaxID: 9557]
NPH1 88L B5L[Gene ID: 2943701 ]
Nucleoside triphosphatase I (EC 3.6.1.15) (NPH-I) (Nucleoside triphosphate phosphohydrolase I) (NPH I)
Yaba Monkey Tumor Virus (strain VR587) (YMTV)
Viruses> DsDNA Viruses> No RNA Stage> Poxviridae> Chordopoxvirinae> Yatapoxvirus> Yaba Monkey Tumor Virus (YMTV)> Yaba Monkey Tumor Virus (strain VR587) (YMTV)
Various pathway(s) in which protein is involved
Not Available
MSRQHAAYIDYALNRMKKMPIEMLGSDTITLKPYQHFVAKVFLGLDTMHSILLFHDTGVGKTITTVFILKHLKDIYTNWTILLLVKKALVEDPWMNTILK
YSPEIIKNCIFINYDDKNFHNKFFTNIKTISSRSRVCVVLDECHNFISKSLIKEDGKQRPTKSVYNYLSKNISLNNNKMICLSATPIVNNVREFTMIVNL
LRPKIIQFQSLFENKNLVNEKELIDKLGGICSYIVNDEFSIFDDVEGSQSFAKKTVYMHYVNMTKQQEIIYQKAKIAEIKSGIASFRIYRRMAATFSFDS
FPDKKKKTIDEITLELGALYKDFVNYVNKKSFSNNAIKLFKSGKGLTGDSNPLDISLLSELRQKSCKFTEVCLKILASPGKCLVFEPFINQSGIEVLLVY
FSVFCITSVEFSSRTKDTRIKNVFEFNKESNTNGEQIKVCVFSISGGEGISFFSINDIFILDMTWNEASLKQIVGRAIRLNSHANTPPNRRYVNVYFIIA
RLSSGEPTVDEDLINIIKTKSKEFFQLFKVFKESSIEWIYKNKKDFYPINDESGWRALTSRVVDVNVKSKRTVQLAQGQNIWFSNSSRMVTIHKGFKTSD
GKIFDVDGNFIQNMPINPIIKIHNDKLVYII
YSPEIIKNCIFINYDDKNFHNKFFTNIKTISSRSRVCVVLDECHNFISKSLIKEDGKQRPTKSVYNYLSKNISLNNNKMICLSATPIVNNVREFTMIVNL
LRPKIIQFQSLFENKNLVNEKELIDKLGGICSYIVNDEFSIFDDVEGSQSFAKKTVYMHYVNMTKQQEIIYQKAKIAEIKSGIASFRIYRRMAATFSFDS
FPDKKKKTIDEITLELGALYKDFVNYVNKKSFSNNAIKLFKSGKGLTGDSNPLDISLLSELRQKSCKFTEVCLKILASPGKCLVFEPFINQSGIEVLLVY
FSVFCITSVEFSSRTKDTRIKNVFEFNKESNTNGEQIKVCVFSISGGEGISFFSINDIFILDMTWNEASLKQIVGRAIRLNSHANTPPNRRYVNVYFIIA
RLSSGEPTVDEDLINIIKTKSKEFFQLFKVFKESSIEWIYKNKKDFYPINDESGWRALTSRVVDVNVKSKRTVQLAQGQNIWFSNSSRMVTIHKGFKTSD
GKIFDVDGNFIQNMPINPIIKIHNDKLVYII
631
Not Available
Not Available
01-05-2000
Inferred from homology
| Amino Acid | Count | % Frequency | Amino Acid | Count | % Frequency |
|---|---|---|---|---|---|
| Alanine (A) | Leucine (L) | ||||
| Arginine (R) | Lysine (K) | ||||
| Asparagine (N) | Methionine (M) | ||||
| Aspartic Acid (D) | Phenylalanine (F) | ||||
| Cysteine (C) | Proline (P) | ||||
| Glutamine (Q) | Serine (S) | ||||
| Glutamic Acid (E) | Threonine (T) | ||||
| Glycine (G) | Tryptophan (W) | ||||
| Histidine (H) | Tyrosine (Y) | ||||
| Isoleucine (I) | Valine (V) |
| % Number of Residues in Helices | % Number of Residues in Strands | % Number of Residues in Coils |
|---|---|---|
DNA-dependent ATPase required for providing the needed energy to achieve the termination of early transcripts. Acts in concert with the RAP94 subunit of the virion RNA polymerase and the capping enzyme/VTF to catalyze release of UUUUUNU-containing nascent RNA from the elongation complex. NPH-I must bind ssDNA in order to exhibit ATPase activity (By similarity).
3.6.1.15
Virion . Note=Virion core enzyme. .
♦DOMAIN 42 204 Helicase ATP-binding.
♦ DOMAIN 367 536 Helicase C-terminal.
♦ DOMAIN 367 536 Helicase C-terminal.
MOTIF 141 144 DEXH box.
Predicted/Modelled
Not Available
Not Available
Protein couldn't be modeled using I-Tasser and Raptor X because of length constraints of the software.
Not Available
- Million Molecules
Best 20 Hit molecules
Not Available