Results | viHumans

UniProt ID

Q8V518

Status

Reviewed

Host

Cynomys Gunnisoni (Gunnison's Prairie Dog) [TaxID: 45479]; Cynomys Leucurus (White-tailed Prairie Dog) [TaxID: 99825]; Cynomys Ludovicianus (Black-tailed Prairie Dog) [TaxID: 45480]; Cynomys Mexicanus (Mexican Prairie Dog) [TaxID: 99826]; Cynomys Parvidens (Utah Prairie Dog) [TaxID: 99827]; Gliridae (dormice) [TaxID: 30650]; Heliosciurus Ruwenzorii (Ruwenzori Sun Squirrel) [TaxID: 226685]; Homo Sapiens (Human) [TaxID: 9606]; Mus Musculus (Mouse) [TaxID: 10090]

Gene Name

I1L[Gene ID: 929042 ]

Protein Name

Telomere-binding protein I1 (36 kDa late protein I1)

Organism Name

Monkeypox Virus (strain Zaire-96-I-16) (MPX)

Taxonomic Lineage

Viruses> DsDNA Viruses> No RNA Stage> Poxviridae> Chordopoxvirinae> Orthopoxvirus> Monkeypox Virus> Monkeypox Virus (strain Zaire-96-I-16) (MPX)

RefSeq

NC_003310.1 ; AF380138.1

PubMed ID

11734207

Pathways Involved

Various pathway(s) in which protein is involved

KEGG

vg:929042

Reactome

Not Available

Sequence

							MAEFEDQLVFNSISARALKAYFTAKINEMVDELVTRKCPQKKKSQAKKPEVRIPVDLVKSSFVKKFGLCNYGGILISLINSLVENNFFTKNGKLDDTGKK
ELVLTDVEKRILNTIDKSSPLYIDISDVKVLAARLKRSATQFNFNGHTYHLENDKIEDLINQLVKDESIQLDEKSSIKDSMYVIPDELIDVLKTRLFRSP
QVKDNIISRTRLYDYFTRVTKRDESSIYVILKDPRIASILSLETVKMGAFMYTKHSMLTNAISSRVDRYSKKFQESFYEDIAEFVKENERVNVSRVVECL
TVPNITISSNTE
						

Length

312

Alternate Sequence

Not Available

Non-standard residue

Not Available

Date of last Sequence modification

01-03-2002

Protein Existence

Evidence at transcript level

Amino Acid composition

Amino Acid	Count	% Frequency	Amino Acid	Count	% Frequency
Alanine (A)			Leucine (L)
Arginine (R)			Lysine (K)
Asparagine (N)			Methionine (M)
Aspartic Acid (D)			Phenylalanine (F)
Cysteine (C)			Proline (P)
Glutamine (Q)			Serine (S)
Glutamic Acid (E)			Threonine (T)
Glycine (G)			Tryptophan (W)
Histidine (H)			Tyrosine (Y)
Isoleucine (I)			Valine (V)

Sum of Absolute Deviation from Amino Acid Occurrence Frequencies

Aliphatic Index

Instability Index

Secondary Structure features

% Number of Residues in Helices	% Number of Residues in Strands	% Number of Residues in Coils

Structural Difficulty(SD) index

Role(s)

Late DNA-binding protein which binds to the hairpin form of the viral telomeric sequence. Required for the production of mature virions (MV) (By similarity).

EC

Not Available

Experimentally known GO terms

GO:0003677 ; GO:0019012

Subcellular Location

Virion . Note=Present in the virus core. .

Domain(s)

Not Available

Motif(s)

Not Available

Methods of 3D structure generation

Predicted/Modelled

Experimetally known structure

Not Available

Active Site(s)

Not Available

Predicted 3D Structures

Protein couldn't be modeled using I-Tasser and Raptor X because of length constraints of the software.

Experimentally known Ligand(s)

Not Available

Virtually Screened Ligands

Virtual screening has been performed using RASPD

						Million Molecules

					
Best 20 Hit molecules 
Not Available