Results | viHumans

UniProt ID

Q8BB47

Status

Reviewed

Host

Homo Sapiens (Human) [TaxID: 9606]

Gene Name

U90/U86

Protein Name

Immediate-early protein 2 (IE2)

Organism Name

Human Herpesvirus 6A (strain GS) (HHV-6 Variant A) (Human B Lymphotropic Virus)

Taxonomic Lineage

Viruses> DsDNA Viruses> No RNA Stage> Herpesvirales> Herpesviridae> Betaherpesvirinae> Roseolovirus> Human Betaherpesvirus 6A> Human Herpesvirus 6A (strain GS) (HHV-6 Variant A) (Human B Lymphotropic Virus)

RefSeq

Not Available

PubMed ID

12706083 ; 16884756 ; 17005699

Pathways Involved

Various pathway(s) in which protein is involved

KEGG

Not Available

Reactome

Not Available

Sequence

							MEPAKPSGNNMGSNDERMQDYRPDPMMEESIQQILEDSLMCDTSFDDLILPGLESFGLIIPESSNNIESNNVEEGSNEDLKTLAEHKCKQGNDNDVIQSA
MKLSGLYCDADITHTQPLSDNTHQDPIYSQETRIFSKTIQDPRIAAQTHRQCTSSASNLPSNESGSTQVRFASELPNQLLQPMYTSHNQNANLQNNFTSL
PYQPYHDPYRDIESSYRESRNTNRGYDYNFRHHSYRPRGGNGKYNYYNPNSKYQQPYKRCFTRTYNRRGRGHRSYDCSDRSADLPYEHYTYPNYEQQNPD
PRMNNYKDFTQLTNKFNFGANDYSMAFSTDSTHVQSDNYNHPTKAQTIPETTKTKKHKATKDNETSRGNQVLTSNDAISLSYRPSPIKLDIIKKIYDTDV
IPLPKEALTANGSNRDVDIQKYKKAHIRCRSVQKKKERSSQTNKHDENHASSRSDLKERKSNEHEDKAVTKARDFSKLDPLLSPLPLTPEPAIDFADHTD
KFYSTPEFNQIKQNLHRSKTSLQDTVPISKHTPRAPTKDNSYKKHHDSKDNYPKMKHSPGRTTSKKNTTNSNGHQNFKDVSVKNVSGKATSTSPKSKTHH
YSSSSDEEGQYKSPVKTITPSPSPYCKLKNPSIMDKNSAKNHTASADKNLTDNSPIRSNLNPTAFNKSNNNKSITNSTSNSDECTDKKPNCNSTKNESKD
PNRTCGKNSDKHLSKSCTMASKRAPSRASSRTSSRASSRASSRASSRASSRASSRASSRDSSRASSRAPSRASSRDSSRASSRDSSRDSNRASSKASSRA
SSRDSSRASSRDSSRASSKASRKASSRASSRASSRASSKASGKASSKASSRASSRAFSRNSSRASSRASSRASSRASSRASSRASSRDSSRALSRAFGRD
SSRASSRASSRDSSRASSKASRKASSRASSRASSRASSRASSRELRQIYCDSNKRQTPPHDTSINTKFEISEIKFRCGEDLNFYKNTAARLQCFNHNDQF
YNPRFRPHIRTNRKKSESTNDTDSESSMSRCKSHCRNSPDSLTIVRRKKHKSGSSSISSSIEENCRSNSHIVTGKEKFTPFYYQSSRTRSSSSSSSSSSA
SLSCSKSTLKTCRKTQNRDNKQIKSKSDSKHKTTNMSSDYESNRHADVFRNSPEAGEKFPLHNSSPFNTHEQSNHSENAIDEEQKKAPNITTSHLHQKQN
VKLHNTKKCKKKRPRDDDSDSSIKNFCKKRISGAQKTESEVSEIDDLCYRDYVRLKERKVSEKFKIHRGRVATKDFQKLFRNTMRAFEYKQIPKKPCNDK
NLKEAVYNICCNGLSNNAAIIMYFTRSKKVAQNIKIMQKELMIRPNITVSEAFKMNHAPPKYYDKDEIKRFIQLQKQGPQELWDKFENNTTHDLFTRHSD
VKTMIIYAATPIDFVGAVKTCNKYAKDNPKEIVLRVCSIIDGDNPISIYNPISKDFKSKFSTLSKC
						

Length

1466

Alternate Sequence

Not Available

Non-standard residue

Not Available

Date of last Sequence modification

01-03-2003

Protein Existence

Evidence at protein level

Amino Acid composition

Amino Acid	Count	% Frequency	Amino Acid	Count	% Frequency
Alanine (A)			Leucine (L)
Arginine (R)			Lysine (K)
Asparagine (N)			Methionine (M)
Aspartic Acid (D)			Phenylalanine (F)
Cysteine (C)			Proline (P)
Glutamine (Q)			Serine (S)
Glutamic Acid (E)			Threonine (T)
Glycine (G)			Tryptophan (W)
Histidine (H)			Tyrosine (Y)
Isoleucine (I)			Valine (V)

Sum of Absolute Deviation from Amino Acid Occurrence Frequencies

Aliphatic Index

Instability Index

Secondary Structure features

% Number of Residues in Helices	% Number of Residues in Strands	% Number of Residues in Coils

Structural Difficulty(SD) index

Role(s)

Transcriptional transactivator.

EC

Not Available

Experimentally known GO terms

GO:0003677 ; GO:0006351 ; GO:0006355 ; GO:0016032 ; GO:0042025

Subcellular Location

Host nucleus .

Domain(s)

Not Available

Motif(s)

Not Available

Methods of 3D structure generation

Predicted/Modelled

Experimetally known structure

Not Available

Active Site(s)

Not Available

Predicted 3D Structures

Protein couldn't be modeled using I-Tasser and Raptor X because of length constraints of the software.

Experimentally known Ligand(s)

Not Available

Virtually Screened Ligands

Virtual screening has been performed using RASPD

						Million Molecules

					
Best 20 Hit molecules 
Not Available