Results | viHumans

UniProt ID

Q77Z83

Status

Reviewed

Host

Homo Sapiens (Human) [TaxID: 9606]

Gene Name

U90/U87/U86 BCLF0

Protein Name

Immediate-early protein 2 (IE2)

Organism Name

Human Herpesvirus 6A (strain Uganda-1102) (HHV-6 Variant A) (Human B Lymphotropic Virus)

Taxonomic Lineage

Viruses> DsDNA Viruses> No RNA Stage> Herpesvirales> Herpesviridae> Betaherpesvirinae> Roseolovirus> Human Betaherpesvirus 6A> Human Herpesvirus 6A (strain Uganda-1102) (HHV-6 Variant A) (Human B Lymphotropic Virus)

RefSeq

Not Available

PubMed ID

7747482 ; 7941342 ; 12367753

Pathways Involved

Various pathway(s) in which protein is involved

KEGG

Not Available

Reactome

Not Available

Sequence

							MEPAKPSGNNMGSNDERMQDYRPDPMMEESIKEILEESLMCDTSFDDLIIPGLESFGLIIPESSNNIESNNVEEGSDGELKTLAEQKCKQGNDNDVIQSA
MKLSGLYCDADITHTQPLSDNTHQDPIYSQESRIFTKTIQDPRIVAQTHRQCTSSASNLQSNESGSTQVRFASELPNQLLQPMYTSHNQNANLQNNFTSL
PYQPYHDPYRDIESSYRESRNTNRGYDYNFRHHPYRPRGGNGKYNYYNPNSKYQQPYKRCFTRTYNRRGRGHRSYDCSDRSADLPYEHYTYPNYEQQNPD
PRMNNYKDFTQLTNKFNFESYDYSMAFSTDSTHVQSDNYNHPTKAQTIPETTKTKKHEATKDNETSTENQVLTPDVISLSYRPSSYKMDIIKKIYDTDVI
PLPKEALTANGSNRDVDIQKYKKAHIRCRSVQKKKERSSQTNKHDENHASSRSDLKERKSNENEDKAVTKARDFSKLNPLLSPLPLTPEPAIDFADHTDK
FYSTPEFNQIQQNLHRSKTSLQDTVPISKHTPRAPTKDNSYKKHHDSKDNYPKMKHSPGRTTSKKNTTNSNGHQNFKEVSVKNVSGKATSTSPKSKTHHY
SSSSDEEGQYKSPVKTIIQSPSPYCKLKNPSIMDKNSAKNHTASADKNLTDNSPIRSNLNPTAFNKSNSNKSITDSTSNSDECTDRKPNCNSTKNESKDP
NRTCGKNSDKHLSKSCTMASKRAPSRASSRASSRDSSRASSRASSRASSRDSSRASSRASSRDSSRASSRASSRASSKASSRASSRASSRASSRDSSRAS
SKASSRASSRDSSRASSRASSRASSKASSRASSRASSRASSRDSSRASSKASSRASSRDSSRASSRDSSRDSSRASSRASSRDSSRASSKASRKASSRAS
SRASSRASSKASGKASSEASSRASSRNSSRASSRASSRASSRDSSRASSRASSRDSSRASSKASRKASSRASSRASSRELRQIYCDSNKRQTPPHDTSIN
TKFEISEIKFRCGEDLNFYKNTAARLQCFNHNDQFYNPRFRPHIRTNRKKSESTNDTDSESSMSRCKSHCRNSPDSLTVVRRKKHKSGSSSISSSIEENC
RSNSHIVTGKEKFTPFYYQSSRTRSSSSSSSSSASLSCSKSTLKTCRKTQYKDNKQIKSKSDSKHKTTNMSSDYESNRHADVFKNSPEAGEKFPLHNSSP
FNTHEQSNHSENAIDEEQKKAPNITTSHLQGKQNVRLHNTKKCKKKRPRDDDSDSSIKNFCKKRISGAQKTESEVSEPDDLCYRDYVRLKERKVSEKFKI
HRGRVATKDFQKLFRNTMRAFEYKQIPKKPCNEKNLKEAVYDICCNGLSNNAAIIMYFTRSKKVAQIIKIMQKELMIRPNITVSEAFKMNHAPPKYYDKD
EIKRFIQLQKQGPQELWDKFENNTTHDLFTRHSDVKTMIIYAATPIDFVGAVKTCNKYAKDNPKEIVLRVCSIIDGDNPISIYNPISKEFKSKFSTLSKC
						

Length

1500

Alternate Sequence

VAR_SEQ 170 1230 Missing (in isoform 4) ; VAR_SEQ 614 1230 Missing (in isoform 3)

Non-standard residue

Not Available

Date of last Sequence modification

22-07-2008

Protein Existence

Evidence at protein level

Amino Acid composition

Amino Acid	Count	% Frequency	Amino Acid	Count	% Frequency
Alanine (A)			Leucine (L)
Arginine (R)			Lysine (K)
Asparagine (N)			Methionine (M)
Aspartic Acid (D)			Phenylalanine (F)
Cysteine (C)			Proline (P)
Glutamine (Q)			Serine (S)
Glutamic Acid (E)			Threonine (T)
Glycine (G)			Tryptophan (W)
Histidine (H)			Tyrosine (Y)
Isoleucine (I)			Valine (V)

Sum of Absolute Deviation from Amino Acid Occurrence Frequencies

Aliphatic Index

Instability Index

Secondary Structure features

% Number of Residues in Helices	% Number of Residues in Strands	% Number of Residues in Coils

Structural Difficulty(SD) index

Role(s)

Transcriptional transactivator.

EC

Not Available

Experimentally known GO terms

GO:0003677 ; GO:0006351 ; GO:0006355 ; GO:0016032 ; GO:0042025

Subcellular Location

Host nucleus .

Domain(s)

Not Available

Motif(s)

Not Available

Methods of 3D structure generation

X-ray crystallography (1)

Experimetally known structure

5WX8

Active Site(s)

Not Available

Predicted 3D Structures

Protein couldn't be modeled using I-Tasser and Raptor X because of length constraints of the software.

Experimentally known Ligand(s)

Not Available

Virtually Screened Ligands

Virtual screening has been performed using RASPD

						Million Molecules

					
Best 20 Hit molecules 
Not Available