Results | viHumans

UniProt ID

Q6TUQ9

Status

Reviewed

Host

Erythrocebus Patas (Red Guenon) (Cercopithecus Patas) [TaxID: 9538]; Homo Sapiens (Human) [TaxID: 9606]; Macaca (macaques) [TaxID: 9539]; Papio Hamadryas (Hamadryas Baboon) [TaxID: 9557]

Gene Name

110R[Gene ID: 2943580 ]

Protein Name

Transcript termination protein A18 (EC 3.6.4.-)

Organism Name

Yaba Monkey Tumor Virus (strain VR587) (YMTV)

Taxonomic Lineage

Viruses> DsDNA Viruses> No RNA Stage> Poxviridae> Chordopoxvirinae> Yatapoxvirus> Yaba Monkey Tumor Virus (YMTV)> Yaba Monkey Tumor Virus (strain VR587) (YMTV)

RefSeq

NC_005179.1 ; AY386371.1

PubMed ID

14645589

Pathways Involved

Various pathway(s) in which protein is involved

KEGG

vg:2943580

Reactome

Not Available

Sequence

							MSVCTEIDYKLYTELRKIAGNSLFLFNEDGDFVEVVSNSSFKFLLPVGLFSSMDIPLKKPIECNTDNDIEHSKNVVMPNLYPFQERVASEVLSSIKKKVE
LKRPMYVTLHLACGFGKTITTCYLLSVHKKKAVICLPNKMLINQWKRAIESININHLVSVDGVGNLLKELVKKPADILIIVSRHLSNKEFCKKIHVDYDV
FVLDESHMYNLMNNSTVTRFLTYYPPKICYFLTATPRRVNRIYCNDVINVSNSSDLKKYIKIVEFFFETYSSDTIRQMVKKLNTNYNKYHMYTEKILAED
VPRNKLILDTIIYDFEKMIVNRLIIVTKLRKHMMFFYTNLIEKFGSDIVYLGDAKNKNISDIVKKIKSINRFIFISTTNYSGTGLDVPTLDSLVICSAVM
NSMQIEQILGRICRYSISKTRTVIVFPNTSIKEIKHMIGFFTQKIITLAIEKLGFKKIDKKGNKQEFALCKAFNLQTR
						

Length

478

Alternate Sequence

Not Available

Non-standard residue

Not Available

Date of last Sequence modification

05-07-2004

Protein Existence

Inferred from homology

Amino Acid composition

Amino Acid	Count	% Frequency	Amino Acid	Count	% Frequency
Alanine (A)			Leucine (L)
Arginine (R)			Lysine (K)
Asparagine (N)			Methionine (M)
Aspartic Acid (D)			Phenylalanine (F)
Cysteine (C)			Proline (P)
Glutamine (Q)			Serine (S)
Glutamic Acid (E)			Threonine (T)
Glycine (G)			Tryptophan (W)
Histidine (H)			Tyrosine (Y)
Isoleucine (I)			Valine (V)

Sum of Absolute Deviation from Amino Acid Occurrence Frequencies

Aliphatic Index

Instability Index

Secondary Structure features

% Number of Residues in Helices	% Number of Residues in Strands	% Number of Residues in Coils

Structural Difficulty(SD) index

Role(s)

DNA helicase which seems to act as a postreplicative transcription termination factor. Involved in ATP-dependent release of nascent RNA. Forms a stable complex with single-stranded DNA, and to a lesser extent RNA (By similarity).

EC

3.6.4.-

Experimentally known GO terms

GO:0003677 ; GO:0004386 ; GO:0005524 ; GO:0006351 ; GO:0019012

Subcellular Location

Virion . Note=Localizes to the virion core. .

Domain(s)

♦DOMAIN 98 254 Helicase ATP-binding.
♦ DOMAIN 307 454 Helicase C-terminal.

Motif(s)

MOTIF 204 207 DESH box.

Methods of 3D structure generation

Predicted/Modelled

Experimetally known structure

Not Available

Active Site(s)

Not Available

Predicted 3D Structures

Protein couldn't be modeled using I-Tasser and Raptor X because of length constraints of the software.

Experimentally known Ligand(s)

Not Available

Virtually Screened Ligands

Virtual screening has been performed using RASPD

						Million Molecules

					
Best 20 Hit molecules 
Not Available