Results | viHumans

UniProt ID

Q6I7B9

Status

Reviewed

Host

Homo Sapiens (Human) [TaxID: 9606]; Sus Scrofa (Pig) [TaxID: 9823]

Gene Name

M[Gene ID: 3077361;3077362 ]

Protein Name

♦Polyprotein p42 [Cleaved into: Protein M1' (CM1') (p31)
♦ Protein CM2]

Organism Name

Influenza C Virus (strain C/Ann Arbor/1/1950)

Taxonomic Lineage

Viruses> SsRNA Viruses> SsRNA Negative-strand Viruses> Orthomyxoviridae> Gammainfluenzavirus> Influenza C Virus> Influenza C Virus (strain C/Ann Arbor/1/1950)

RefSeq

NC_006307.2 ; AB126193.2 ; NC_006308.2 ; AB126196.2 ; NC_006309.2 ; AB126191.2 ; NC_006310.2 ;
AB283001.1 ; NC_006311.1 ; AB126195.1 ; NC_006312.2 ; AB126191.2 ; NC_006306.2 ; AB283001.1

PubMed ID

15218173 ; 9356355 ; 9847305 ; 11297683 ; 21106743

Pathways Involved

Various pathway(s) in which protein is involved

KEGG

vg:3077361;vg:3077362

Reactome

Not Available

Sequence

							MAHEILIAETEAFLKNVAPETRTAIISAITGGKSACKSAAKLIKNEHLPLMSGEATTMHIVMRCLYPEIKPWKKASDMLNKATSSLKKSEGRDIRKQMKA
AGDFLGVESMMKMRAFRDDQIMEMVEEVYDHPDDYTPDIRIGTITAWLRCKNKKSERYRSNVSESGRTALKIHEVRKASTAMNEIAGITGLGEEALSLQR
QTESLAILCNHTFGSNIMRPHLEKAIKGVEGRVGEMGRMAMKWLVVIICFSITSQPASACNLKTCLKLFNNTDAVTVHCFNENQGYMLTLASLGLGIITM
LYLLVKIIIELVNGFVLGRWERWCGDIKTTIMPEIDSMEKDIALSRERLDLGEDAPDETDNSPIPFSNDGIFEI
						

Length

374

Alternate Sequence

VAR_SEQ 243 374 Missing (in isoform M1)

Non-standard residue

Not Available

Date of last Sequence modification

09-01-2007

Protein Existence

Evidence at protein level

Amino Acid composition

Amino Acid	Count	% Frequency	Amino Acid	Count	% Frequency
Alanine (A)			Leucine (L)
Arginine (R)			Lysine (K)
Asparagine (N)			Methionine (M)
Aspartic Acid (D)			Phenylalanine (F)
Cysteine (C)			Proline (P)
Glutamine (Q)			Serine (S)
Glutamic Acid (E)			Threonine (T)
Glycine (G)			Tryptophan (W)
Histidine (H)			Tyrosine (Y)
Isoleucine (I)			Valine (V)

Sum of Absolute Deviation from Amino Acid Occurrence Frequencies

Aliphatic Index

Instability Index

Secondary Structure features

% Number of Residues in Helices	% Number of Residues in Strands	% Number of Residues in Coils

Structural Difficulty(SD) index

Role(s)

Ion channel, which might have a role in genome packaging and uncoating processes.

EC

Not Available

Experimentally known GO terms

GO:0005216 ; GO:0016021 ; GO:0019028 ; GO:0020002 ; GO:0039660 ;
GO:0039707 ; GO:0044167 ; GO:0044385 ; GO:0051259 ; GO:0055036

Subcellular Location

♦ Polyprotein p42: Host endoplasmic reticulum membrane
♦ Multi-pass membrane protein .
♦ Protein M1': Virion membrane
♦ Single-pass type II membrane protein .
♦ Protein CM2: Virion membrane
♦ Single-pass type I membrane protein . Host cell membrane
♦ Single-pass type I membrane protein .

Domain(s)

Not Available

Motif(s)

Not Available

Methods of 3D structure generation

X-ray crystallography (1)

Experimetally known structure

5M1M

Active Site(s)

Not Available

Predicted 3D Structures

Protein couldn't be modeled using I-Tasser and Raptor X because of length constraints of the software.

Experimentally known Ligand(s)

Not Available

Virtually Screened Ligands

Virtual screening has been performed using RASPD

						Million Molecules

					
Best 20 Hit molecules 
Not Available