Results | viHumans

UniProt ID

Q50LE4

Status

Reviewed

Host

Homo Sapiens (Human) [TaxID: 9606]

Gene Name

Not Available

Protein Name

Potential RNA-dependent RNA polymerase (EC 2.7.7.48)

Organism Name

Human Picobirnavirus (strain Human/Thailand/Hy005102/-) (PBV)

Taxonomic Lineage

Viruses> DsRNA Viruses> Picobirnaviridae> Picobirnavirus> Human Picobirnavirus> Human Picobirnavirus (strain Human/Thailand/Hy005102/-) (PBV)

RefSeq

Not Available

PubMed ID

15847933

Pathways Involved

Various pathway(s) in which protein is involved

KEGG

vg:5075908

Reactome

Not Available

Sequence

							MQVAPNVWSKYFNIPNPGLRAYFSNVVSGQPEVYRTPFYKGMSLESICDEWYKKLVSIDTQWPTLMEFEDDLRKKVGPMSVMLPLKERMSDIDSYYDSIS
KDQVPFDTKAISAAKSEWKGVSRLRLRSEVNTVAVMKKSTNSGSPYFSKRKAVVSKTIPCDVYMDGRYCVMRQNGREWSGAAVLGWRGQEGGPKPTDVKQ
RVVWMFPFAVNIRELQVYQPLILTFQRLGLVPAWVSMEAVDRRITKMFDTKGPRDVVVCTDFSKFDQHFNPTCQSVAKELLADLLTGQEAVDWLERVFPI
KYAIPLAYNWGEIRYGIHGMGSGSGGTNADETLVHRVLQHEAAISHHTTLNPNSQCLGDDGVLTYPGISAEDVMQSYSRHGLDMNLEKQYVSKQDCTYLR
RWHHTDYRVDGMCVGVYSTMRALGRLAMQERYYDPDVWGEKMVTLRYLSIIENVKYHPLKEEFLDFCIKGDKTRLGLGIPGFLDNIAGEAQKAIDMMPDF
LGYTKSLQYDGDLRRNAAAGIENWWVVQALKSRR
						

Length

534

Alternate Sequence

Not Available

Non-standard residue

Not Available

Date of last Sequence modification

07-06-2005

Protein Existence

Evidence at protein level

Amino Acid composition

Amino Acid	Count	% Frequency	Amino Acid	Count	% Frequency
Alanine (A)			Leucine (L)
Arginine (R)			Lysine (K)
Asparagine (N)			Methionine (M)
Aspartic Acid (D)			Phenylalanine (F)
Cysteine (C)			Proline (P)
Glutamine (Q)			Serine (S)
Glutamic Acid (E)			Threonine (T)
Glycine (G)			Tryptophan (W)
Histidine (H)			Tyrosine (Y)
Isoleucine (I)			Valine (V)

Sum of Absolute Deviation from Amino Acid Occurrence Frequencies

Aliphatic Index

Instability Index

Secondary Structure features

% Number of Residues in Helices	% Number of Residues in Strands	% Number of Residues in Coils

Structural Difficulty(SD) index

Role(s)

RNA-directed RNA polymerase that is involved in both transcription and genome replication.

EC

2.7.7.48

Experimentally known GO terms

GO:0000166 ; GO:0003723 ; GO:0003968 ; GO:0006351 ; GO:0019012

Subcellular Location

Virion .

Domain(s)

DOMAIN 255 373 RdRp catalytic.

Motif(s)

Not Available

Methods of 3D structure generation

X-ray crystallography (2)

Experimetally known structure

5I61 5I62

Active Site(s)

Not Available

Predicted 3D Structures

Protein couldn't be modeled using I-Tasser and Raptor X because of length constraints of the software.

Experimentally known Ligand(s)

Not Available

Virtually Screened Ligands

Virtual screening has been performed using RASPD

						Million Molecules

					
Best 20 Hit molecules 
Not Available