Results | viHumans

UniProt ID

Q4JQW8

Status

Reviewed

Host

Homo Sapiens (Human) [TaxID: 9606]

Gene Name

ORF7[Gene ID: 1487677 ]

Protein Name

Tegument protein UL51 homolog (Protein ORF7)

Organism Name

Varicella-zoster Virus (strain Oka Vaccine) (HHV-3) (Human Herpesvirus 3)

Taxonomic Lineage

Viruses> DsDNA Viruses> No RNA Stage> Herpesvirales> Herpesviridae> Alphaherpesvirinae> Varicellovirus> Human Herpesvirus 3 (HHV-3) (Varicella-zoster Virus)> Varicella-zoster Virus (strain Oka Vaccine) (HHV-3) (Human Herpesvirus 3)

RefSeq

NC_001348.1 ; X04370.1

PubMed ID

12388706 ; 18787000 ; 28356523 ; 29116592

Pathways Involved

Various pathway(s) in which protein is involved

KEGG

vg:1487677

Reactome

Not Available

Sequence

							MQTVCASLCGYARIPTEEPSYEEVRVNTHPQGAALLRLQEALTAVNGLLPAPLTLEDVVASADNTRRLVRAQALARTYAACSRNIECLKQHHFTEDNPGL
NAVVRSHMENSKRLADMCLAAITHLYLSVGAVDVTTDDIVDQTLRMTAESEVVMSDVVLLEKTLGVVAKPQASFDVSHNHELSIAKGENVGLKTSPIKSE
ATQLSEIKPPLIEVSDNNTSNLTKKTYPTETLQPVLTPKQTQDVQRTTPAIKKSHVMLV
						

Length

259

Alternate Sequence

Not Available

Non-standard residue

Not Available

Date of last Sequence modification

24-03-2009

Protein Existence

Evidence at protein level

Amino Acid composition

Amino Acid	Count	% Frequency	Amino Acid	Count	% Frequency
Alanine (A)			Leucine (L)
Arginine (R)			Lysine (K)
Asparagine (N)			Methionine (M)
Aspartic Acid (D)			Phenylalanine (F)
Cysteine (C)			Proline (P)
Glutamine (Q)			Serine (S)
Glutamic Acid (E)			Threonine (T)
Glycine (G)			Tryptophan (W)
Histidine (H)			Tyrosine (Y)
Isoleucine (I)			Valine (V)

Sum of Absolute Deviation from Amino Acid Occurrence Frequencies

Aliphatic Index

Instability Index

Secondary Structure features

% Number of Residues in Helices	% Number of Residues in Strands	% Number of Residues in Coils

Structural Difficulty(SD) index

Role(s)

Plays several roles during the time course of infection, including egress of virus particles from the perinuclear space and secondary envelopment of cytoplasmic capsids that bud into specific trans-Golgi network (TGN)-derived membranes (PubMed:28356523). Localizes its binding partner ORF53 to the host trans-Golgi network (TGN) (PubMed:29116592).

EC

Not Available

Experimentally known GO terms

GO:0019033 ; GO:0044177

Subcellular Location

Virion . Virion tegument . Host cytoplasm . Host Golgi apparatus .

Domain(s)

Not Available

Motif(s)

Not Available

Methods of 3D structure generation

Predicted/Modelled

Experimetally known structure

Not Available

Active Site(s)

Not Available

Predicted 3D Structures

Protein couldn't be modeled using I-Tasser and Raptor X because of length constraints of the software.

Experimentally known Ligand(s)

Not Available

Virtually Screened Ligands

Virtual screening has been performed using RASPD

						Million Molecules

					
Best 20 Hit molecules 
Not Available