Reviewed
Homo Sapiens (Human) [TaxID: 9606]
TRM1 ORF7[Gene ID: 4961505 ]
Tripartite terminase subunit 1
Human Herpesvirus 8 Type P (isolate GK18) (HHV-8) (Kaposi's Sarcoma-associated Herpesvirus)
Viruses> DsDNA Viruses> No RNA Stage> Herpesvirales> Herpesviridae> Gammaherpesvirinae> Rhadinovirus> Human Herpesvirus 8 (HHV-8) (Kaposi's Sarcoma-associated Herpesvirus)> Human Herpesvirus 8 Type P (isolate GK18) (HHV-8) (Kaposi's Sarcoma-associated Herpesvirus)
Various pathway(s) in which protein is involved
Not Available
MAKELAAVYADVSALAMDLCLLSYADPATLDTKSLALTTGKFQSLHGTLLPLLRRQNAHECSGLSLELEHLLENVADALTTLGVCTSRKLSPEEHFSLLH
LDITCNKHRSVRFNFYGNWALELKLSLINDVEIFFKRLSSVFYCIGSGSALEGLGEVLRFVGKLRGISPVPGPDLYVSNLPCLECLQEVCLTPNQGTSLQ
AMLPDTACSHICTPACGEPVRGLFENELKQLGLQTPESIPTTPCQSRVRQDDEIRQSSLMAVGDHHIFGEVTRSVLEISNLIYWSSGHSDATCDGDRDCS
HLASLFTHEADMHKRRVDLAGCLGERGTPKHFFDCFRPDSLETLFCGGLFSSVEDTIESLQKDCSSAFYQQVNYTTALQKQNEFYVRLSKLLAAGQLNLG
KCSTESCPSEARRQLVGGDKPEEVLRDAKHRQELYLQKVARDGFKKLSDCIRHQGHILSQTLGLRLWGSVIYNEASALQNHFLHRAQFISLPWQDLTVDC
PTRFENSKYIKNSLYCQRLGREHVEILTLEFYKLITGPLSKRHTLFPSPPNVTLAQCFEAAGMLPHQKMMVSEMIWPSIEPKDWIEPNFNQFYSFENQDI
NHLQKRAWEYIRELVLSVSLYNRTWERELKILLTPQGSPGFKEPKPAGLTTGLYLTFETSAPLVLVDKKYGWIFKDLYALLYHHLQLSNHNDSQV
LDITCNKHRSVRFNFYGNWALELKLSLINDVEIFFKRLSSVFYCIGSGSALEGLGEVLRFVGKLRGISPVPGPDLYVSNLPCLECLQEVCLTPNQGTSLQ
AMLPDTACSHICTPACGEPVRGLFENELKQLGLQTPESIPTTPCQSRVRQDDEIRQSSLMAVGDHHIFGEVTRSVLEISNLIYWSSGHSDATCDGDRDCS
HLASLFTHEADMHKRRVDLAGCLGERGTPKHFFDCFRPDSLETLFCGGLFSSVEDTIESLQKDCSSAFYQQVNYTTALQKQNEFYVRLSKLLAAGQLNLG
KCSTESCPSEARRQLVGGDKPEEVLRDAKHRQELYLQKVARDGFKKLSDCIRHQGHILSQTLGLRLWGSVIYNEASALQNHFLHRAQFISLPWQDLTVDC
PTRFENSKYIKNSLYCQRLGREHVEILTLEFYKLITGPLSKRHTLFPSPPNVTLAQCFEAAGMLPHQKMMVSEMIWPSIEPKDWIEPNFNQFYSFENQDI
NHLQKRAWEYIRELVLSVSLYNRTWERELKILLTPQGSPGFKEPKPAGLTTGLYLTFETSAPLVLVDKKYGWIFKDLYALLYHHLQLSNHNDSQV
695
Not Available
Not Available
21-03-2006
Inferred from homology
| Amino Acid | Count | % Frequency | Amino Acid | Count | % Frequency |
|---|---|---|---|---|---|
| Alanine (A) | Leucine (L) | ||||
| Arginine (R) | Lysine (K) | ||||
| Asparagine (N) | Methionine (M) | ||||
| Aspartic Acid (D) | Phenylalanine (F) | ||||
| Cysteine (C) | Proline (P) | ||||
| Glutamine (Q) | Serine (S) | ||||
| Glutamic Acid (E) | Threonine (T) | ||||
| Glycine (G) | Tryptophan (W) | ||||
| Histidine (H) | Tyrosine (Y) | ||||
| Isoleucine (I) | Valine (V) |
| % Number of Residues in Helices | % Number of Residues in Strands | % Number of Residues in Coils |
|---|---|---|
Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging. Forms a tripartite terminase complex together with TRM2 and TRM3 in the host cytoplasm. Once the complex reaches the host nucleus, it interacts with the capsid portal vertex. This portal forms a ring in which genomic DNA is translocated into the capsid. TRM1 carries an endonuclease activity that plays an important role for the cleavage of concatemeric viral DNA into unit length genomes.
Not Available
Host nucleus . Note=Found associated with the external surface of the viral capsid during assembly and DNA packaging, but seems absent in extracellular mature virions. .
Not Available
Not Available
Predicted/Modelled
Not Available
Not Available
Protein couldn't be modeled using I-Tasser and Raptor X because of length constraints of the software.
Not Available
- Million Molecules
Best 20 Hit molecules
Not Available