Results | viHumans

UniProt ID

Q2F8F7

Status

Reviewed

Host

Capra Hircus (Goat) [TaxID: 9925]; Homo Sapiens (Human) [TaxID: 9606]; Ovis Aries (Sheep) [TaxID: 9940]

Gene Name

PAPL

Protein Name

Poly(A) polymerase catalytic subunit (EC 2.7.7.19) (Poly(A) polymerase large subunit) (PAP-L)

Organism Name

Orf Virus (strain NZ2) (OV NZ-2)

Taxonomic Lineage

Viruses> DsDNA Viruses> No RNA Stage> Poxviridae> Chordopoxvirinae> Parapoxvirus> Orf Virus (ORFV)> Orf Virus (strain NZ2) (OV NZ-2)

RefSeq

NC_005336.1 ; AY386264.1

PubMed ID

16274827

Pathways Involved

Various pathway(s) in which protein is involved

KEGG

Not Available

Reactome

Not Available

Sequence

							MAPPVIEEYLGSRPSMERCVLLRAQRRNMTRVLNFDRKLFLSLVVKSRRRFFKKLGGSEKEIAARIEEYFSRQRRLEKLGQILTVLELQSVIVSEFTRTL
GSLTTPTPAINAAVRRVDAPRARALASRALNSYAVLPPPEEAAPMARHKHSDLVEVVKRLVKEHLRRHNKRCVCYGSYALHLLNPEIEYGDIDMVQTNAR
PFLINLAFLIYFVTGRQTVLLRVPYLKNYVVLQDEEGGHILDSFNVRQATLRALPTLLVDNIYVLHPFVQLMAMLKMFSQTDRIRDLADNFDKARARMET
LLAFALEELGEAPADGRTPLPCAFLPPEGGASRVLEADARALDCGFARAVVFLDEPALVQTLLDMGVQDDEIVDFESVSNSAFLVRDNTLFTYFSNTVLM
DGDAVHDLSRRGVSAHIVMFLLLTRHPAAEGAVRSMLGSLVSDARPVTSVVERERKTGTHGVIDIAKNVITH
						

Length

472

Alternate Sequence

Not Available

Non-standard residue

Not Available

Date of last Sequence modification

21-03-2006

Protein Existence

Inferred from homology

Amino Acid composition

Amino Acid	Count	% Frequency	Amino Acid	Count	% Frequency
Alanine (A)			Leucine (L)
Arginine (R)			Lysine (K)
Asparagine (N)			Methionine (M)
Aspartic Acid (D)			Phenylalanine (F)
Cysteine (C)			Proline (P)
Glutamine (Q)			Serine (S)
Glutamic Acid (E)			Threonine (T)
Glycine (G)			Tryptophan (W)
Histidine (H)			Tyrosine (Y)
Isoleucine (I)			Valine (V)

Sum of Absolute Deviation from Amino Acid Occurrence Frequencies

Aliphatic Index

Instability Index

Secondary Structure features

% Number of Residues in Helices	% Number of Residues in Strands	% Number of Residues in Coils

Structural Difficulty(SD) index

Role(s)

Polymerase that creates the 3'-poly(A) tail of mRNA's.

EC

2.7.7.19

Experimentally known GO terms

GO:0004652 ; GO:0005524 ; GO:0006351 ; GO:0006397

Subcellular Location

Not Available

Domain(s)

Not Available

Motif(s)

Not Available

Methods of 3D structure generation

Predicted/Modelled

Experimetally known structure

Not Available

Active Site(s)

♦ACT_SITE 191 191
♦ ACT_SITE 193 193

Predicted 3D Structures

Protein couldn't be modeled using I-Tasser and Raptor X because of length constraints of the software.

Experimentally known Ligand(s)

Not Available

Virtually Screened Ligands

Virtual screening has been performed using RASPD

						Million Molecules

					
Best 20 Hit molecules 
Not Available