Results | viHumans

UniProt ID

Q1HVG4

Status

Reviewed

Host

Homo Sapiens (Human) [TaxID: 9606]

Gene Name

EBNA4 BERF2A-BERF2B

Protein Name

Epstein-Barr nuclear antigen 4 (EBNA-4) (EBV nuclear antigen 4) (Epstein-Barr nuclear antigen 3B) (EBNA-3B) (EBV nuclear antigen 3B)

Organism Name

Epstein-Barr Virus (strain AG876) (HHV-4) (Human Herpesvirus 4)

Taxonomic Lineage

Viruses> DsDNA Viruses> No RNA Stage> Herpesvirales> Herpesviridae> Gammaherpesvirinae> Lymphocryptovirus> Epstein-Barr Virus (strain GD1) (HHV-4) (Human Herpesvirus 4)> Epstein-Barr Virus (strain AG876) (HHV-4) (Human Herpesvirus 4)

RefSeq

NC_007605.1 ; AJ507799.2

PubMed ID

16490228

Pathways Involved

Various pathway(s) in which protein is involved

KEGG

Not Available

Reactome

Not Available

Sequence

							MKKAWLSRAQQADAGGASGSEDPPDYGDQGNVQQVGSDPISPAIGPFELSAASEDDPQSGPVEENLDAAAREEEEPDEQEHNGGDDPLEVHTRQPRFVDV
NPTQAPVIQLVHAVYDSMLQSDLRSLGSLFLEQNLNIEEFIWMCMTVRHRCQAIRQKPLPIDKQRRWKLLSPYRTWRMGYRTQTLNVNSFETGGDKVHPL
LVTATLGCEEGLRHAITYSAGIVQLPRMSDQNQKIETAFLMARRARSLSAERYTLFFDLVSSGNTLYAIWIGLGTRNRVAFVEFVGWLCKKDHTHIREWF
RQCTGRPSPSKPWMRAHPVAVPYDDPLTSEETDLAYARGLAMSIEAARLPDDPIIVEDDDESEEIEDKCDKDEEESGTEDVTSIPQTLPHSPTVYGRPSV
FYRKPDTKSTKKCRAIVTDLSIIKVIEDEHRKKKTARTEQPRAKPDSPAPTVVLRRPPTQKVTGPAGSLSVQAQLEPWQPLSWPHETRVILHGPPTQGDQ
AHGSMLDLLEKDDQHMEQQVMATLLPPEPHQPRSGRRAPCVYTADLDIESDEPATSEPVLDQLLPAPGLGPLAIQPLTSPTTSQLRSSAPSHAQTPWPVT
HPSQTPGGPTTQSLAPETEAPRQWPMPLRPIPLHPLRMQPISFNPAVRPTPHQPPQVEPTFYQSTWVKPPQQYQPQMGHIPYQPRPTGHSTMLRPQWAPT
TMQPPPRAPTPMPPPQGPPTAMQRPQGAPTPMPPPQGPPTAMQRPRGAPTPMPPPQGPPTAMQLSPRALTGQKGPAKHILRQLLTGGVKSGRPSLKFKAA
LERQAAAGLRPSPGSGTGAKIVQAPVFYPPVLQPIQVMWQVGSSKAVAASTVTQAPTEYTGERRLGGPMSPTDIPPSKRVKKKAYPERKTPHGGPSHSST
VMWENVSQGQQQTLECGGTDKQERNMLGMGDIAVSSPSSSETSNDE
						

Length

946

Alternate Sequence

Not Available

Non-standard residue

Not Available

Date of last Sequence modification

26-05-2009

Protein Existence

Inferred from homology

Amino Acid composition

Amino Acid	Count	% Frequency	Amino Acid	Count	% Frequency
Alanine (A)			Leucine (L)
Arginine (R)			Lysine (K)
Asparagine (N)			Methionine (M)
Aspartic Acid (D)			Phenylalanine (F)
Cysteine (C)			Proline (P)
Glutamine (Q)			Serine (S)
Glutamic Acid (E)			Threonine (T)
Glycine (G)			Tryptophan (W)
Histidine (H)			Tyrosine (Y)
Isoleucine (I)			Valine (V)

Sum of Absolute Deviation from Amino Acid Occurrence Frequencies

Aliphatic Index

Instability Index

Secondary Structure features

% Number of Residues in Helices	% Number of Residues in Strands	% Number of Residues in Coils

Structural Difficulty(SD) index

Role(s)

May be involved in transcriptional regulation of both viral and cellular genes by interacting with the host DNA-binding protein RBPJ.

EC

Not Available

Experimentally known GO terms

GO:0006351 ; GO:0006355 ; GO:0016032 ; GO:0042025

Subcellular Location

Host nucleus.

Domain(s)

Not Available

Motif(s)

Not Available

Methods of 3D structure generation

Predicted/Modelled

Experimetally known structure

Not Available

Active Site(s)

Not Available

Predicted 3D Structures

Protein couldn't be modeled using I-Tasser and Raptor X because of length constraints of the software.

Experimentally known Ligand(s)

Not Available

Virtually Screened Ligands

Virtual screening has been performed using RASPD

						Million Molecules

					
Best 20 Hit molecules 
Not Available