Reviewed
Amblyomma Variegatum (Tropical Bont Tick) [TaxID: 34610]; Homo Sapiens (Human) [TaxID: 9606]; Hyalomma Rufipes [TaxID: 72862]; Hyalomma Truncatum [TaxID: 72855]; Rhipicephalus [TaxID: 34630]; Rhipicephalus Annulatus [TaxID: 34611]; Rhipicephalus Decoloratus (African Blue Tick) (Boophilus Decoloratus) [TaxID: 60189]; Rhipicephalus Geigyi [TaxID: 136141]
GP
♦Envelopment polyprotein (M polyprotein) [Cleaved into: Mucin-like variable region
♦ GP38
♦ Glycoprotein N (Gn) (Glycoprotein G2)
♦ Non-Structural protein M (NSm)
♦ Glycoprotein C (Gc) (Glycoprotein G1)]
♦ GP38
♦ Glycoprotein N (Gn) (Glycoprotein G2)
♦ Non-Structural protein M (NSm)
♦ Glycoprotein C (Gc) (Glycoprotein G1)]
Dugbe Virus (isolate ArD44313) (DUGV)
Viruses> SsRNA Viruses> SsRNA Negative-strand Viruses> Bunyavirales> Nairoviridae> Orthonairovirus> Dugbe Virus> Dugbe Virus (isolate ArD44313) (DUGV)
Various pathway(s) in which protein is involved
Not Available
Not Available
MSKRVLIIAVVVYLVFTTQNQITGNHTTINSSSPSTTEASSTPTVSRTPQTTTTSTAVSTTITATTTPTASWTTQSQYFNKTTQHHWREETMISRNPTVL
DRQSRASSVRELLNTKFLMLLGFIPKGEVNHLENACNREGKNCTELILKERIARFFSETEKESCYNTYLEKHLRSVSPEVSLTPYRVLGLREDILLKEID
RRIIRFETDSQRVTCLSASLLKPDVFIREQRIDAKPSNGPKIVPVDSVACMNLEANVDVRSNKLVIQSLMTTVKISLKNCKVVVNSRQCIHQQTGSGVIK
VPKFEKQQGGTWSSYIAGVYTATIDLLDENNQNCKLFTECIVKGRELVKGQSELKSFNIEVLLPRVMKTRRKLLAVTDGSTECNSGTQLIEGKSIEVHKQ
DIGGPGKKLTICNGTSVLDVPLDEGHGCYTINVITSKRACRPKNSKLQCSIDKELKPCDSGKCLSISQKGAGHIKVSRGKTILITECKEHCQIPVPTGKG
DIMVDCSGGRQHYLEVNIVDIHCPNTKFLGGIMLYFCRMSSRPTVALLLGIWIGCGYILTCIFSFLLYHLILFFANCIKQCRKKGERLGEICVKCEQQTV
NLMDQELHDLNCNFNLCPYCCNRMSDEGMSRHVGKCPKRLERLNEIELYLTTSECLCLSVCYQLLISVGIFLKRTTWLVVLLVLLGLAISPVQGAPTEVS
NVKQDGDYSICYFIFGCLVTAALLLKVKRTNSNGIVVVVDSFGRCPYCNEFTDSLFEEVLHDTLCSLCVCPFCEKQALDLVTLEEHVKECYKVATRKDIF
KILGRKFTNALVRREKLFTTGLQLFINKTNVVVFALIMCFLLLLTGHNASAFDSGDLPDGVWEESSQLVKSCTQFCYIEEDVCYCPAEDGVGRKLLFFNG
LQNSVKRLSDSHKLLTSVSIDAPWGRINVESTWKPTLAASNIAMSWSSTDIKGEKVILSGRSTSIIKLKEKTGVMWKLVGSGLASEKKKPFRFPIMDFAQ
VYNSVFQYITGDRLLSEWPKAVCTGDCPHRCGCQTSTCMAKECHTQECVSTHMVLGIGTGCTCCGMDVERPFNKYLGVKWSTEYLRTEVLVCVEVTEEER
HCEIVEAGTRFNIGPITITISDPQNIGSKLPESLMTVQEIDDSNFVDIMHVGNVISADNSCRLQSCTHGSAVTTRFTALTALIKDDHSSGLNLAVLDPKV
NSSWLSWEGCDMDYYCNVGDWPTCTYTGVVTQKLREFLKLDQHRKRLHTTLSFSLKKNLSKRSHTSVRLEGKTVTRMEVKVTALIEVDGMELHSKTIRLS
GIRLTGLKCSGCFSCTSGISCSVNAKLTSPDEFTLHLRSTSPNVVVAETSIIARKGPSATTSRFKVFSVRDTKKICFEVVEREYCKDCTPDELTTCTGVE
LEPTKDILLEHRGTIVQHQNDTCKSKIDCWSNSISSFASGIGDFFKHYIGSIAVGVLGTVLPFALLILFFIYGDKMLWPFKVFCRPCRRCCRKNEGYNKL
AEEEELRDIIRKFSKSGELINKDAKDKRTLARLFMSDNPKLKKEKKLSEIA
DRQSRASSVRELLNTKFLMLLGFIPKGEVNHLENACNREGKNCTELILKERIARFFSETEKESCYNTYLEKHLRSVSPEVSLTPYRVLGLREDILLKEID
RRIIRFETDSQRVTCLSASLLKPDVFIREQRIDAKPSNGPKIVPVDSVACMNLEANVDVRSNKLVIQSLMTTVKISLKNCKVVVNSRQCIHQQTGSGVIK
VPKFEKQQGGTWSSYIAGVYTATIDLLDENNQNCKLFTECIVKGRELVKGQSELKSFNIEVLLPRVMKTRRKLLAVTDGSTECNSGTQLIEGKSIEVHKQ
DIGGPGKKLTICNGTSVLDVPLDEGHGCYTINVITSKRACRPKNSKLQCSIDKELKPCDSGKCLSISQKGAGHIKVSRGKTILITECKEHCQIPVPTGKG
DIMVDCSGGRQHYLEVNIVDIHCPNTKFLGGIMLYFCRMSSRPTVALLLGIWIGCGYILTCIFSFLLYHLILFFANCIKQCRKKGERLGEICVKCEQQTV
NLMDQELHDLNCNFNLCPYCCNRMSDEGMSRHVGKCPKRLERLNEIELYLTTSECLCLSVCYQLLISVGIFLKRTTWLVVLLVLLGLAISPVQGAPTEVS
NVKQDGDYSICYFIFGCLVTAALLLKVKRTNSNGIVVVVDSFGRCPYCNEFTDSLFEEVLHDTLCSLCVCPFCEKQALDLVTLEEHVKECYKVATRKDIF
KILGRKFTNALVRREKLFTTGLQLFINKTNVVVFALIMCFLLLLTGHNASAFDSGDLPDGVWEESSQLVKSCTQFCYIEEDVCYCPAEDGVGRKLLFFNG
LQNSVKRLSDSHKLLTSVSIDAPWGRINVESTWKPTLAASNIAMSWSSTDIKGEKVILSGRSTSIIKLKEKTGVMWKLVGSGLASEKKKPFRFPIMDFAQ
VYNSVFQYITGDRLLSEWPKAVCTGDCPHRCGCQTSTCMAKECHTQECVSTHMVLGIGTGCTCCGMDVERPFNKYLGVKWSTEYLRTEVLVCVEVTEEER
HCEIVEAGTRFNIGPITITISDPQNIGSKLPESLMTVQEIDDSNFVDIMHVGNVISADNSCRLQSCTHGSAVTTRFTALTALIKDDHSSGLNLAVLDPKV
NSSWLSWEGCDMDYYCNVGDWPTCTYTGVVTQKLREFLKLDQHRKRLHTTLSFSLKKNLSKRSHTSVRLEGKTVTRMEVKVTALIEVDGMELHSKTIRLS
GIRLTGLKCSGCFSCTSGISCSVNAKLTSPDEFTLHLRSTSPNVVVAETSIIARKGPSATTSRFKVFSVRDTKKICFEVVEREYCKDCTPDELTTCTGVE
LEPTKDILLEHRGTIVQHQNDTCKSKIDCWSNSISSFASGIGDFFKHYIGSIAVGVLGTVLPFALLILFFIYGDKMLWPFKVFCRPCRRCCRKNEGYNKL
AEEEELRDIIRKFSKSGELINKDAKDKRTLARLFMSDNPKLKKEKKLSEIA
1551
Not Available
Not Available
01-07-1993
Evidence at protein level
| Amino Acid | Count | % Frequency | Amino Acid | Count | % Frequency |
|---|---|---|---|---|---|
| Alanine (A) | Leucine (L) | ||||
| Arginine (R) | Lysine (K) | ||||
| Asparagine (N) | Methionine (M) | ||||
| Aspartic Acid (D) | Phenylalanine (F) | ||||
| Cysteine (C) | Proline (P) | ||||
| Glutamine (Q) | Serine (S) | ||||
| Glutamic Acid (E) | Threonine (T) | ||||
| Glycine (G) | Tryptophan (W) | ||||
| Histidine (H) | Tyrosine (Y) | ||||
| Isoleucine (I) | Valine (V) |
| % Number of Residues in Helices | % Number of Residues in Strands | % Number of Residues in Coils |
|---|---|---|
Glycoprotein C and glycoprotein N interact with each other and are present at the surface of the virion. They are able to attach the virion to a cell receptor and to promote fusion of membranes after endocytosis of the virion (By similarity).
Not Available
♦ Glycoprotein C: Virion membrane
♦ Single-pass type I membrane protein . Host Golgi apparatus membrane
♦ Single-pass type I membrane protein . Host endoplasmic reticulum membrane
♦ Single-pass type I membrane protein . Note=Interaction between Glycoprotein C and Glycoprotein N is essential for proper targeting of Glycoprotein C to the Golgi complex, where virion budding occurs. .
♦ Glycoprotein N: Virion membrane
♦ Multi-pass membrane protein . Host Golgi apparatus membrane
♦ Multi-pass membrane protein .
♦ Single-pass type I membrane protein . Host Golgi apparatus membrane
♦ Single-pass type I membrane protein . Host endoplasmic reticulum membrane
♦ Single-pass type I membrane protein . Note=Interaction between Glycoprotein C and Glycoprotein N is essential for proper targeting of Glycoprotein C to the Golgi complex, where virion budding occurs. .
♦ Glycoprotein N: Virion membrane
♦ Multi-pass membrane protein . Host Golgi apparatus membrane
♦ Multi-pass membrane protein .
Not Available
Not Available
Predicted/Modelled
Not Available
Not Available
Protein couldn't be modeled using I-Tasser and Raptor X because of length constraints of the software.
Not Available
- Million Molecules
Best 20 Hit molecules
Not Available