Reviewed
Homo Sapiens (Human) [TaxID: 9606]
UL42[Gene ID: 1487329 ]
DNA polymerase processivity factor (DNA-binding protein UL42) (Polymerase accessory protein) (PAP)
Human Herpesvirus 2 (strain HG52) (HHV-2) (Human Herpes Simplex Virus 2)
Viruses> DsDNA Viruses> No RNA Stage> Herpesvirales> Herpesviridae> Alphaherpesvirinae> Simplexvirus> Human Herpesvirus 2 (HHV-2) (Human Herpes Simplex Virus 2)> Human Herpesvirus 2 (strain HG52) (HHV-2) (Human Herpes Simplex Virus 2)
Not Available
Various pathway(s) in which protein is involved
Not Available
MAHLPGGAAAAPLSEDAIPSPRERTEDWPPCQIVLQGAELNGILQAFAPLRTSLLDSLLVVGDRGILVHNAIFGEQVFLPLDHSQFSRYRWGGPTAAFLS
LVDQKRSLLSVFRANQYPDLRRVELTVTGQAPFRTLVQRIWTTASDGEAVELASETLMKRELTSFAVLLPQGDPDVQLRLTKPQLTKVVNAVGDETAKPT
TFELGPNGKFSVFNARTCVTFAAREEGASSSTSAQVQILTSALKKAGQAAANAKTVYGENTHRTFSVVVDDCSMRAVLRRLQVGGGTLKFFLTADVPSVC
VTATGPNAVSAVFLLKPQRVCLNWLGRSPGSSTGSLASQDSRAGPTDSQDSSSEPDAGDRGAPEEEGLEGQARVPPAFPEPPGTKRRHPGAEVVPADDAT
KRPKTGVPAAPTRAESPPLSARYGPEAAEGGGDGGRYACYFRDLQTGDASPSPLSAFRGPQRPPYGFGLP
LVDQKRSLLSVFRANQYPDLRRVELTVTGQAPFRTLVQRIWTTASDGEAVELASETLMKRELTSFAVLLPQGDPDVQLRLTKPQLTKVVNAVGDETAKPT
TFELGPNGKFSVFNARTCVTFAAREEGASSSTSAQVQILTSALKKAGQAAANAKTVYGENTHRTFSVVVDDCSMRAVLRRLQVGGGTLKFFLTADVPSVC
VTATGPNAVSAVFLLKPQRVCLNWLGRSPGSSTGSLASQDSRAGPTDSQDSSSEPDAGDRGAPEEEGLEGQARVPPAFPEPPGTKRRHPGAEVVPADDAT
KRPKTGVPAAPTRAESPPLSARYGPEAAEGGGDGGRYACYFRDLQTGDASPSPLSAFRGPQRPPYGFGLP
470
Not Available
Not Available
01-05-1997
Inferred from homology
| Amino Acid | Count | % Frequency | Amino Acid | Count | % Frequency |
|---|---|---|---|---|---|
| Alanine (A) | Leucine (L) | ||||
| Arginine (R) | Lysine (K) | ||||
| Asparagine (N) | Methionine (M) | ||||
| Aspartic Acid (D) | Phenylalanine (F) | ||||
| Cysteine (C) | Proline (P) | ||||
| Glutamine (Q) | Serine (S) | ||||
| Glutamic Acid (E) | Threonine (T) | ||||
| Glycine (G) | Tryptophan (W) | ||||
| Histidine (H) | Tyrosine (Y) | ||||
| Isoleucine (I) | Valine (V) |
| % Number of Residues in Helices | % Number of Residues in Strands | % Number of Residues in Coils |
|---|---|---|
Plays an essential role in viral DNA replication by acting as the polymerase accessory subunit. Associates with the viral polymerase to increase its processivity and forms high-affinity direct interactions with DNA. Facilitates the origin-binding protein loading onto DNA thus increasing its ability to assemble into a functional complex capable of unwinding duplex DNA (By similarity).
Not Available
Host nucleus .
Not Available
MOTIF 385 404 Bipartite nuclear localization signal.
Predicted/Modelled
Not Available
Not Available
Protein couldn't be modeled using I-Tasser and Raptor X because of length constraints of the software.
Not Available
- Million Molecules
Best 20 Hit molecules
Not Available