Reviewed
Homo Sapiens (Human) [TaxID: 9606]
UL16
Cytoplasmic envelopment protein 2
Human Herpesvirus 2 (strain HG52) (HHV-2) (Human Herpes Simplex Virus 2)
Viruses> DsDNA Viruses> No RNA Stage> Herpesvirales> Herpesviridae> Alphaherpesvirinae> Simplexvirus> Human Herpesvirus 2 (HHV-2) (Human Herpes Simplex Virus 2)> Human Herpesvirus 2 (strain HG52) (HHV-2) (Human Herpes Simplex Virus 2)
Not Available
Various pathway(s) in which protein is involved
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MAQRALWRPQATPGPPGAAAPPGHRGAPPDARAPDPGPEADLVARIANSVFVWRVVRGDERLKIFRCLTVLTEPLCQVALPDPDPERALFCEIFLYLTRP
KALRLPSNTFFAIFFFNRERRYCATVHLRSVTHPRTPLLCTLAFGHLEAASPPEETPDPAAEQLADEPVAHELDGAYLVPTDTAPESGACCALGPGAWWH
LPGGRIYCWAMDDDLGSLCPPGSRARHLGWLLSRITDPPGGGGACAPTAHIDSANALWRAPAVAEACPCVAPCMWSNMAQRTLAVRGDASLCQLLFGHPV
DAVILRQATRRPRITAHLHEVVVGRDGAESVIRPTSAGWRLCVLSSYTSRLFATSCPAVARAVARASSSDYK
KALRLPSNTFFAIFFFNRERRYCATVHLRSVTHPRTPLLCTLAFGHLEAASPPEETPDPAAEQLADEPVAHELDGAYLVPTDTAPESGACCALGPGAWWH
LPGGRIYCWAMDDDLGSLCPPGSRARHLGWLLSRITDPPGGGGACAPTAHIDSANALWRAPAVAEACPCVAPCMWSNMAQRTLAVRGDASLCQLLFGHPV
DAVILRQATRRPRITAHLHEVVVGRDGAESVIRPTSAGWRLCVLSSYTSRLFATSCPAVARAVARASSSDYK
372
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01-05-1997
Inferred from homology
Amino Acid | Count | % Frequency | Amino Acid | Count | % Frequency |
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Alanine (A) | Leucine (L) | ||||
Arginine (R) | Lysine (K) | ||||
Asparagine (N) | Methionine (M) | ||||
Aspartic Acid (D) | Phenylalanine (F) | ||||
Cysteine (C) | Proline (P) | ||||
Glutamine (Q) | Serine (S) | ||||
Glutamic Acid (E) | Threonine (T) | ||||
Glycine (G) | Tryptophan (W) | ||||
Histidine (H) | Tyrosine (Y) | ||||
Isoleucine (I) | Valine (V) |
% Number of Residues in Helices | % Number of Residues in Strands | % Number of Residues in Coils |
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Plays a critical role in cytoplasmic virus egress. Participates in the final step of tegumentation and envelope acquisition within the host cytoplasm by directly interacting with the capsid. Upon virion binding to target cell, a signaling cascade is triggered to disrupt the interaction with the capsid, thereby preparing capsid uncoating.
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Virion tegument . Host cytoplasm , . Host nucleus , . Note=Localizes in the host nucleus up to 18 hours postinfection, but at later times localizes to punctate, cytoplasmic structures. .
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Predicted/Modelled
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Protein couldn't be modeled using I-Tasser and Raptor X because of length constraints of the software.
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- Million Molecules
Best 20 Hit molecules
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