Reviewed
Homo Sapiens (Human) [TaxID: 9606]
UL9
Replication origin-binding protein (OBP) (OriBP)
Human Herpesvirus 2 (strain HG52) (HHV-2) (Human Herpes Simplex Virus 2)
Viruses> DsDNA Viruses> No RNA Stage> Herpesvirales> Herpesviridae> Alphaherpesvirinae> Simplexvirus> Human Herpesvirus 2 (HHV-2) (Human Herpes Simplex Virus 2)> Human Herpesvirus 2 (strain HG52) (HHV-2) (Human Herpes Simplex Virus 2)
Not Available
Various pathway(s) in which protein is involved
Not Available
Not Available
MNVATCTHQTHHAARAPGATSAPGAASGDPLGARRPIGDDECEQYTSSVSLARMLYGGDLAEWVPRVHPKTTIERQQHGPVTFPDASAPTARCVTVVRAP
MGSGKTTALIRWLGEAIHSPDTSVLVVSCRRSFTQTLATRFAESGLPDFVTYFSSTNYIMNDRPFHRLIVQVESLHRVGPNLLNNYDVLVLDEVMSTLGQ
LYSPTMQQLGRVDALMLRLLRTCPRIIAMDATANAQLVDFLCSLRGEKNVHVVIGEYAMPGFSARRCLFLPRLGPEVLQAALRRRGPAGGAPPPDAPPDA
TFFGELEARLAGGDNVCIFSSTVSFAEVVARFCRQFTDRVLLLHSLTPPGDVTTWGRYRVVIYTTVVTVGLSFDPPHFDSMFAYVKPMNYGPDMVSVYQS
LGRVRTLRKGELLIYMDGSGARSEPVFTPMLLNHVVSASGQWPAQFSQVTNLLCRRFKGRCDASHADAAQARGSRIYSKFRYKHYFERCTLACLADSLNI
LHMLLTLNCMHVRFWGHDAALTPRNFCLFLRGIHFDALRAQRDLRELRCQDPDTSLSAQAAETEEVGLFVEKYLRPDVAPAEVVALMRGLNSLVGRTRFI
YLVLLEACLRVPMAAHSSAIFRRLYDHYATGVIPTINAAGELELVALHPTLNVAPVWELFRLCSTMAACLQWDSMAGGSGRTFSPEDVLELLNPHYDRYM
QLVFELGHCNVTDGPLLSEDAVKRVADALSGCPPRGSVSETEHALSLFKIIWGELFGVQLAKSTQTFPGAGRVKNLTKRAIVELLDAHRIDHSACRTHRQ
LYALLMAHKREFAGARFKLRAPAWGRCLRTHASGAQPNTDIILEAALSELPTEAWPMMQGAVNFSTL
MGSGKTTALIRWLGEAIHSPDTSVLVVSCRRSFTQTLATRFAESGLPDFVTYFSSTNYIMNDRPFHRLIVQVESLHRVGPNLLNNYDVLVLDEVMSTLGQ
LYSPTMQQLGRVDALMLRLLRTCPRIIAMDATANAQLVDFLCSLRGEKNVHVVIGEYAMPGFSARRCLFLPRLGPEVLQAALRRRGPAGGAPPPDAPPDA
TFFGELEARLAGGDNVCIFSSTVSFAEVVARFCRQFTDRVLLLHSLTPPGDVTTWGRYRVVIYTTVVTVGLSFDPPHFDSMFAYVKPMNYGPDMVSVYQS
LGRVRTLRKGELLIYMDGSGARSEPVFTPMLLNHVVSASGQWPAQFSQVTNLLCRRFKGRCDASHADAAQARGSRIYSKFRYKHYFERCTLACLADSLNI
LHMLLTLNCMHVRFWGHDAALTPRNFCLFLRGIHFDALRAQRDLRELRCQDPDTSLSAQAAETEEVGLFVEKYLRPDVAPAEVVALMRGLNSLVGRTRFI
YLVLLEACLRVPMAAHSSAIFRRLYDHYATGVIPTINAAGELELVALHPTLNVAPVWELFRLCSTMAACLQWDSMAGGSGRTFSPEDVLELLNPHYDRYM
QLVFELGHCNVTDGPLLSEDAVKRVADALSGCPPRGSVSETEHALSLFKIIWGELFGVQLAKSTQTFPGAGRVKNLTKRAIVELLDAHRIDHSACRTHRQ
LYALLMAHKREFAGARFKLRAPAWGRCLRTHASGAQPNTDIILEAALSELPTEAWPMMQGAVNFSTL
867
Not Available
Not Available
01-05-2000
Inferred from homology
| Amino Acid | Count | % Frequency | Amino Acid | Count | % Frequency |
|---|---|---|---|---|---|
| Alanine (A) | Leucine (L) | ||||
| Arginine (R) | Lysine (K) | ||||
| Asparagine (N) | Methionine (M) | ||||
| Aspartic Acid (D) | Phenylalanine (F) | ||||
| Cysteine (C) | Proline (P) | ||||
| Glutamine (Q) | Serine (S) | ||||
| Glutamic Acid (E) | Threonine (T) | ||||
| Glycine (G) | Tryptophan (W) | ||||
| Histidine (H) | Tyrosine (Y) | ||||
| Isoleucine (I) | Valine (V) |
| % Number of Residues in Helices | % Number of Residues in Strands | % Number of Residues in Coils |
|---|---|---|
Functions as a docking protein to recruit essential components of the viral replication machinery to viral DNA origins. In the presence of the major DNA-binding protein, opens dsDNA leading to a conformational change in the origin that facilitates DNA unwinding and subsequent replication.
Not Available
Host nucleus .
DOMAIN 86 251 Helicase ATP-binding.
Not Available
Predicted/Modelled
Not Available
Not Available
Protein couldn't be modeled using I-Tasser and Raptor X because of length constraints of the software.
Not Available
- Million Molecules
Best 20 Hit molecules
Not Available