Results | viHumans

UniProt ID

P59596

Status

Reviewed

Host

Homo Sapiens (Human) [TaxID: 9606]; Paguma Larvata (Masked Palm Civet) [TaxID: 9675]

Gene Name

M 5[Gene ID: 1489672 ]

Protein Name

Membrane protein (M protein) (E1 glycoprotein) (Matrix glycoprotein) (Membrane glycoprotein)

Organism Name

Human SARS Coronavirus (SARS-CoV) (Severe Acute Respiratory Syndrome Coronavirus)

Taxonomic Lineage

Viruses> SsRNA Viruses> SsRNA Positive-strand Viruses> No DNA Stage> Nidovirales> Coronaviridae> Coronavirinae> Betacoronavirus> Severe Acute Respiratory Syndrome-related Coronavirus> Human SARS Coronavirus (SARS-CoV) (Severe Acute Respiratory Syndrome Coronavirus)

RefSeq

NC_004718.3 ; AY274119.3

PubMed ID

12730500 ; 12730501 ; 12853594 ; 12958366 ; 12876307 ; 12781537 ; 12917450 ; 15194747 ; 15763150 ;
16580632

Pathways Involved

Various pathway(s) in which protein is involved

KEGG

vg:1489672

Reactome

Not Available

Sequence

							MADNGTITVEELKQLLEQWNLVIGFLFLAWIMLLQFAYSNRNRFLYIIKLVFLWLLWPVTLACFVLAAVYRINWVTGGIAIAMACIVGLMWLSYFVASFR
LFARTRSMWSFNPETNILLNVPLRGTIVTRPLMESELVIGAVIIRGHLRMAGHSLGRCDIKDLPKEITVATSRTLSYYKLGASQRVGTDSGFAAYNRYRI
GNYKLNTDHAGSNDNIALLVQ
						

Length

221

Alternate Sequence

Not Available

Non-standard residue

Not Available

Date of last Sequence modification

23-04-2003

Protein Existence

Evidence at protein level

Amino Acid composition

Amino Acid	Count	% Frequency	Amino Acid	Count	% Frequency
Alanine (A)			Leucine (L)
Arginine (R)			Lysine (K)
Asparagine (N)			Methionine (M)
Aspartic Acid (D)			Phenylalanine (F)
Cysteine (C)			Proline (P)
Glutamine (Q)			Serine (S)
Glutamic Acid (E)			Threonine (T)
Glycine (G)			Tryptophan (W)
Histidine (H)			Tyrosine (Y)
Isoleucine (I)			Valine (V)

Sum of Absolute Deviation from Amino Acid Occurrence Frequencies

Aliphatic Index

Instability Index

Secondary Structure features

% Number of Residues in Helices	% Number of Residues in Strands	% Number of Residues in Coils

Structural Difficulty(SD) index

Role(s)

Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins.

EC

Not Available

Experimentally known GO terms

GO:0016021 ; GO:0019031 ; GO:0019058 ; GO:0039503 ; GO:0039547 ;
GO:0039660 ; GO:0044178 ; GO:0055036

Subcellular Location

♦ Virion membrane
♦ Multi-pass membrane protein . Host Golgi apparatus membrane
♦ Multi-pass membrane protein . Note=Largely embedded in the lipid bilayer. .

Domain(s)

Not Available

Motif(s)

Not Available

Methods of 3D structure generation

X-ray crystallography (1)

Experimetally known structure

3I6G

Active Site(s)

Not Available

Predicted 3D Structures

Protein couldn't be modeled using I-Tasser and Raptor X because of length constraints of the software.

Experimentally known Ligand(s)

Not Available

Virtually Screened Ligands

Virtual screening has been performed using RASPD

						Million Molecules

					
Best 20 Hit molecules 
Not Available