Results | viHumans

UniProt ID

P52539

Status

Reviewed

Host

Homo Sapiens (Human) [TaxID: 9606]

Gene Name

KA3L U42[Gene ID: 1497044 ]

Protein Name

mRNA export factor ICP27 homolog

Organism Name

Human Herpesvirus 6B (strain Z29) (HHV-6 Variant B) (Human B Lymphotropic Virus)

Taxonomic Lineage

Viruses> DsDNA Viruses> No RNA Stage> Herpesvirales> Herpesviridae> Betaherpesvirinae> Roseolovirus> Human Herpesvirus 6B (HHV-6 Variant B) (Human B Lymphotropic Virus)> Human Herpesvirus 6B (strain Z29) (HHV-6 Variant B) (Human B Lymphotropic Virus)

RefSeq

NC_000898.1 ; AF157706.1

PubMed ID

7983761 ; 10482553

Pathways Involved

Various pathway(s) in which protein is involved

KEGG

vg:1497044

Reactome

Not Available

Sequence

							MYPRGVKRSQHDRHKQTAFRTIKRSITHRPTSKFISHFAKNFRGKLAPLKQLDESRLDALSLTELEQLKTIIEEKQQEKRAQNNAITFLPNLPTVPFADT
NFSIKSLGLRPYNGDARDPKQRIRDRFPQTHERICLLTNDILETDLLLRYRQCLDSLTREENQQLMGDRIFSLTNSPCLAFTVATVEEACSYFKFHDLHN
LPVNPQDLFMYTITVMKFEFFNKLNMAKLTCVFNDNGHGDIEYRKLRQLCGKPVLDREMPNSEFEVQQQTPDSFRHPIQQAMSIVVTFARILRQIKEHII
RTKKPQFIRDFDTERVAERYECGLISRLIGKQFSNHKCDDVSCQNRIERIMAPWKPSLFFCTYFAKDAPKFKLFPNLPHEYRNLSFTCPKVDMEPSCSYS
TSRDLPQTSHRSHKNQGTPKVKSKVCVEKPDTSNLTTTKTTTEILIEESMETDNKIPDPRELNFNQAKQDEIVIININENVNSKHESESSVEMDLDLDYE
ADTCETNLNTYSSDSE
						

Length

516

Alternate Sequence

Not Available

Non-standard residue

Not Available

Date of last Sequence modification

01-10-1996

Protein Existence

Inferred from homology

Amino Acid composition

Amino Acid	Count	% Frequency	Amino Acid	Count	% Frequency
Alanine (A)			Leucine (L)
Arginine (R)			Lysine (K)
Asparagine (N)			Methionine (M)
Aspartic Acid (D)			Phenylalanine (F)
Cysteine (C)			Proline (P)
Glutamine (Q)			Serine (S)
Glutamic Acid (E)			Threonine (T)
Glycine (G)			Tryptophan (W)
Histidine (H)			Tyrosine (Y)
Isoleucine (I)			Valine (V)

Sum of Absolute Deviation from Amino Acid Occurrence Frequencies

Aliphatic Index

Instability Index

Secondary Structure features

% Number of Residues in Helices	% Number of Residues in Strands	% Number of Residues in Coils

Structural Difficulty(SD) index

Role(s)

Immediate early (EI) protein that plays many roles during productive infection including regulation of viral gene expression and nuclear export of intronless viral RNAs.

EC

Not Available

Experimentally known GO terms

GO:0006351 ; GO:0006355 ; GO:0019033 ; GO:0030430 ; GO:0042025 ;
GO:0046872

Subcellular Location

Virion tegument . Virion . Host nucleus. Host cytoplasm. Note=Shuttles between host nucleus and cytoplasm.

Domain(s)

Not Available

Motif(s)

Not Available

Methods of 3D structure generation

Predicted/Modelled

Experimetally known structure

Not Available

Active Site(s)

Not Available

Predicted 3D Structures

Protein couldn't be modeled using I-Tasser and Raptor X because of length constraints of the software.

Experimentally known Ligand(s)

Not Available

Virtually Screened Ligands

Virtual screening has been performed using RASPD

						Million Molecules

					
Best 20 Hit molecules 
Not Available