Results | viHumans

UniProt ID

P52537

Status

Reviewed

Host

Homo Sapiens (Human) [TaxID: 9606]

Gene Name

CVC2 KA11R U50[Gene ID: 1497052 ]

Protein Name

Capsid vertex component 2

Organism Name

Human Herpesvirus 6B (strain Z29) (HHV-6 Variant B) (Human B Lymphotropic Virus)

Taxonomic Lineage

Viruses> DsDNA Viruses> No RNA Stage> Herpesvirales> Herpesviridae> Betaherpesvirinae> Roseolovirus> Human Herpesvirus 6B (HHV-6 Variant B) (Human B Lymphotropic Virus)> Human Herpesvirus 6B (strain Z29) (HHV-6 Variant B) (Human B Lymphotropic Virus)

RefSeq

NC_000898.1 ; AF157706.1

PubMed ID

7983761 ; 10482553

Pathways Involved

Various pathway(s) in which protein is involved

KEGG

vg:1497052

Reactome

Not Available

Sequence

							MAQCNLFYQYPITPILEGHVRNILICTEEDIRRLQSQSSLRLREKIDQGHRDKLLRMRLKTELDALQRKMQKDSDVLNSHLKAIEDALLFTNDGEVNVET
KADTQLLPKSPERLEKFNQVAITPLDPFIRFTDDFRGEMINTFFNNAQMWNFTFGSWFYKLKRVFYNEPGLRRALKITNVDSLTISKELLTVTVNALEQA
TVYPIFGSEMSDLEAALCILAAFYSTYENSQIDERTTLVDIITLLPVIFRLLGSEITALKNVSPSGTYFGFNDPSCMKFFVPMRKGKHYAENTFGNHVLV
KMLLGRGVMQKIPGEKDSQNFDVEARLHGAIKNDVLVYWTYQLMRPKLGNNVPIFIHDQHYLRSGLVAIESLFLLWRILNSESLFNKRVGKFLLTSIFPQ
LENVDFAENNFEAGNIQNFEYLMHHYVVPMYNLQNDISISTLFPGLVAVCVNESVRLGWEHKCAGAPSDAVQVQSKENPFVEYIRAQMEQQADVAILEKH
DCILFHFENGLNITLSFTLPRQRLFAMASSLFNVNDTYDFIYFLVLGFLPIPAII
						

Length

555

Alternate Sequence

Not Available

Non-standard residue

Not Available

Date of last Sequence modification

01-10-1996

Protein Existence

Inferred from homology

Amino Acid composition

Amino Acid	Count	% Frequency	Amino Acid	Count	% Frequency
Alanine (A)			Leucine (L)
Arginine (R)			Lysine (K)
Asparagine (N)			Methionine (M)
Aspartic Acid (D)			Phenylalanine (F)
Cysteine (C)			Proline (P)
Glutamine (Q)			Serine (S)
Glutamic Acid (E)			Threonine (T)
Glycine (G)			Tryptophan (W)
Histidine (H)			Tyrosine (Y)
Isoleucine (I)			Valine (V)

Sum of Absolute Deviation from Amino Acid Occurrence Frequencies

Aliphatic Index

Instability Index

Secondary Structure features

% Number of Residues in Helices	% Number of Residues in Strands	% Number of Residues in Coils

Structural Difficulty(SD) index

Role(s)

Capsid vertex-specific component that plays a role during viral DNA encapsidation, assuring correct genome cleavage and presumably stabilizing capsids that contain full-length viral genomes. Participates in the interaction between the capsid and the tegument through interaction with the large tegument protein/LTP.

EC

Not Available

Experimentally known GO terms

GO:0019028 ; GO:0019072 ; GO:0042025 ; GO:0046718 ; GO:0075732

Subcellular Location

Virion . Host nucleus .

Domain(s)

Not Available

Motif(s)

Not Available

Methods of 3D structure generation

Predicted/Modelled

Experimetally known structure

Not Available

Active Site(s)

Not Available

Predicted 3D Structures

Protein couldn't be modeled using I-Tasser and Raptor X because of length constraints of the software.

Experimentally known Ligand(s)

Not Available

Virtually Screened Ligands

Virtual screening has been performed using RASPD

						Million Molecules

					
Best 20 Hit molecules 
Not Available