Results | viHumans

UniProt ID

P52379

Status

Reviewed

Host

Homo Sapiens (Human) [TaxID: 9606]

Gene Name

U73

Protein Name

Replication origin-binding protein (OBP)

Organism Name

Human Herpesvirus 7 (strain JI) (HHV-7) (Human T Lymphotropic Virus)

Taxonomic Lineage

Viruses> DsDNA Viruses> No RNA Stage> Herpesvirales> Herpesviridae> Betaherpesvirinae> Roseolovirus> Human Betaherpesvirus 7> Human Herpesvirus 7 (strain JI) (HHV-7) (Human T Lymphotropic Virus)

RefSeq

NC_001716.2 ; AF037218.1

PubMed ID

8709220

Pathways Involved

Various pathway(s) in which protein is involved

KEGG

Not Available

Reactome

Not Available

Sequence

							METQLQNDQLFLEWFGQNLLDCHFAQNVSVYLQDASMVHFKTFSEQIKIIRAPMGSGKTSALIEFLKTVSYIDSVLVISCRKTFAAELLNRFKKNDLNDF
YLYSEIKERQINKNKLIIQVESLHRVTRNYHVLILDEIMSIIKQFYSKTMTKVKEVDAKLLTLIRNSTQIVAMDATVNRYVVDFFSLCMPHFKSALIINT
FVSANFSNRSAYFCPTFIDGNLAFYGILKQKLGLGKNICLFCSTVTSADFMSELLKTDFPDKKILLLTSKQGKCHSVESWINYNIVIYTSIVTVGLSFDF
LHFSAMFVYIHLVKGGPDMVSVFQSMGRVRKVTDNEIFIYLNPALIQVPLSVSPISIPQCYDWTLFEKSILQCSCMDFNKKCLSAQNYLSNSMIKQFFRI
RHYIEKTTLLNLPDSLYLLCLLLDSNSIKVHIDGDVFPIAKEKFYAFTKMLVQGCHFFEKKKTDFVENTMTLKELFSNTNITVNGEFYELGNFQVHKDYI
VNLNNFQNLFLKNDVDIFVIEEIMLTLKSEIRRFVFINALLQKYVATGIDVEKIKAFFKSRIKTFTLPENYICSKFYLLSDISGVHECGMLMDVAFLAES
IRADLNLQSCTDTQTDISEDAILLCAARRSSEILRILQIVFTTHVQLFEKYNSYTLYLFNRLKGMQLNTWSLSIAKFSVSIIRMFFKCAFNMNLVKSKPR
YIVGKPFRSLTKREIETLLDMWHVSRTNLKTYKELRKALTEASKKRQRKKIYKLLGHNISSYISETGCLFQHADAGMCLSSGCLLRS
						

Length

787

Alternate Sequence

Not Available

Non-standard residue

Not Available

Date of last Sequence modification

01-10-1996

Protein Existence

Inferred from homology

Amino Acid composition

Amino Acid	Count	% Frequency	Amino Acid	Count	% Frequency
Alanine (A)			Leucine (L)
Arginine (R)			Lysine (K)
Asparagine (N)			Methionine (M)
Aspartic Acid (D)			Phenylalanine (F)
Cysteine (C)			Proline (P)
Glutamine (Q)			Serine (S)
Glutamic Acid (E)			Threonine (T)
Glycine (G)			Tryptophan (W)
Histidine (H)			Tyrosine (Y)
Isoleucine (I)			Valine (V)

Sum of Absolute Deviation from Amino Acid Occurrence Frequencies

Aliphatic Index

Instability Index

Secondary Structure features

% Number of Residues in Helices	% Number of Residues in Strands	% Number of Residues in Coils

Structural Difficulty(SD) index

Role(s)

Probably involved in DNA replication. Binds the origin of replication (ori) (By similarity).

EC

Not Available

Experimentally known GO terms

GO:0003688 ; GO:0005524 ; GO:0006260

Subcellular Location

Not Available

Domain(s)

DOMAIN 39 195 Helicase ATP-binding.

Motif(s)

Not Available

Methods of 3D structure generation

Predicted/Modelled

Experimetally known structure

Not Available

Active Site(s)

Not Available

Predicted 3D Structures

Protein couldn't be modeled using I-Tasser and Raptor X because of length constraints of the software.

Experimentally known Ligand(s)

Not Available

Virtually Screened Ligands

Virtual screening has been performed using RASPD

						Million Molecules

					
Best 20 Hit molecules 
Not Available