Results | viHumans

UniProt ID

P36713

Status

Reviewed

Host

Homo Sapiens (Human) [TaxID: 9606]

Gene Name

L4[Gene ID: 1460842 ]

Protein Name

♦Pre-hexon-linking protein VIII (Pre-protein VIII) (pVIII) [Cleaved into: Hexon-linking protein-N (12.1 kDa protein VIII) (Protein VIII-N)
♦ Hexon-linking protein-C (7.6 kDa protein VIII) (Protein VIII-C)]

Organism Name

Human Adenovirus A Serotype 12 (HAdV-12) (Human Adenovirus 12)

Taxonomic Lineage

Viruses> DsDNA Viruses> No RNA Stage> Adenoviridae> Mastadenovirus> Human Mastadenovirus A> Human Adenovirus A Serotype 12 (HAdV-12) (Human Adenovirus 12)

RefSeq

NC_001460.1 ; X73487.1

PubMed ID

8254750 ; 8438575

Pathways Involved

Various pathway(s) in which protein is involved

KEGG

Not Available

Reactome

Not Available

Sequence

							MSKDIPTPYMWSFQPQMGLAAGAAQDYSSKMNWLSAGPHMISRVNGVRARRNQILLEQAALTATPRNQLNPPSWPAALIYQENPPPTTVLLPRDAQAEVH
MTNAGAQLAGGARHSFRYKGRTEPYPSPAIKRVLIRGKGIQLNDEVTSPLGVRPDGVFQLGGSGRSSFTARQAYLTLQSSSSAPRSGGIGTLQFVEEFTP
SVYFNPFSGSPGHYPDAFIPNFDAVSESVDGYD
						

Length

233

Alternate Sequence

Not Available

Non-standard residue

Not Available

Date of last Sequence modification

01-06-1994

Protein Existence

Evidence at protein level

Amino Acid composition

Amino Acid	Count	% Frequency	Amino Acid	Count	% Frequency
Alanine (A)			Leucine (L)
Arginine (R)			Lysine (K)
Asparagine (N)			Methionine (M)
Aspartic Acid (D)			Phenylalanine (F)
Cysteine (C)			Proline (P)
Glutamine (Q)			Serine (S)
Glutamic Acid (E)			Threonine (T)
Glycine (G)			Tryptophan (W)
Histidine (H)			Tyrosine (Y)
Isoleucine (I)			Valine (V)

Sum of Absolute Deviation from Amino Acid Occurrence Frequencies

Aliphatic Index

Instability Index

Secondary Structure features

% Number of Residues in Helices	% Number of Residues in Strands	% Number of Residues in Coils

Structural Difficulty(SD) index

Role(s)

♦Hexon-linking protein-N: Structural component of the virion that acts as a cement protein on the capsid interior and which glue the peripentonal hexons and group-of-nine hexons together.
♦ Hexon-linking protein-C: Structural component of the virion that acts as a cement protein on the capsid interior and which glue the peripentonal hexons and group-of-nine hexons together.

EC

Not Available

Experimentally known GO terms

GO:0019028 ; GO:0031423 ; GO:0042025

Subcellular Location

♦ Hexon-linking protein-C: Virion . Note=Located on the inner side of the capsid shell. Present in 120 copies per virion. .
♦ Pre-hexon-linking protein VIII: Host nucleus .
♦ Hexon-linking protein-N: Virion . Note=Located on the inner side of the capsid shell. Present in 120 copies per virion. .

Domain(s)

Not Available

Motif(s)

Not Available

Methods of 3D structure generation

Predicted/Modelled

Experimetally known structure

Not Available

Active Site(s)

Not Available

Predicted 3D Structures

Protein couldn't be modeled using I-Tasser and Raptor X because of length constraints of the software.

Experimentally known Ligand(s)

Not Available

Virtually Screened Ligands

Virtual screening has been performed using RASPD

						Million Molecules

					
Best 20 Hit molecules 
Not Available