Results | viHumans

UniProt ID

P33870

Status

Reviewed

Host

Homo Sapiens (Human) [TaxID: 9606]

Gene Name

C15L F11L[Gene ID: 1486571 ]

Protein Name

Protein F11

Organism Name

Variola Virus (isolate Human/India/Ind3/1967) (VARV) (Smallpox Virus)

Taxonomic Lineage

Viruses> DsDNA Viruses> No RNA Stage> Poxviridae> Chordopoxvirinae> Orthopoxvirus> Variola Virus> Variola Virus (isolate Human/India/Ind3/1967) (VARV) (Smallpox Virus)

RefSeq

NC_001611.1 ; X69198.1

PubMed ID

8109158 ; 8384129 ; 8264798

Pathways Involved

Various pathway(s) in which protein is involved

KEGG

vg:1486571

Reactome

Not Available

Sequence

							MGFCIPLRLKMLKRGSRKFSSMLARRHTPKKMNIVTDLENRLKKNSYIENTNQGNILMDSIFVSTMSVETLFGSYITDDSDDYELKDLLNVTYNIKPVIV
PDIKLDAVLDRDGNFRPADCFLVKLKHRDGFTKGALYLGHSAGFTATICLKNEGVSGLYIPGTSVIRTNICQGDTIVSRSSRGVQFLLQIGGEAIFLIVS
LCPTKKLVETGFVIPNISSNDNAKIAARILSEKRKDTITHIDTLIQYGQQLELAYYNSCMLTEFLHYCNLYANTIKESLLKETIQKDINITHTNITTLLN
ETAKVIKLVKSLVDKEDTDIVNNFITKEIKNCGGVKNRDTIVNSLSLSNLDFYL
						

Length

354

Alternate Sequence

Not Available

Non-standard residue

Not Available

Date of last Sequence modification

01-02-1994

Protein Existence

Inferred from homology

Amino Acid composition

Amino Acid	Count	% Frequency	Amino Acid	Count	% Frequency
Alanine (A)			Leucine (L)
Arginine (R)			Lysine (K)
Asparagine (N)			Methionine (M)
Aspartic Acid (D)			Phenylalanine (F)
Cysteine (C)			Proline (P)
Glutamine (Q)			Serine (S)
Glutamic Acid (E)			Threonine (T)
Glycine (G)			Tryptophan (W)
Histidine (H)			Tyrosine (Y)
Isoleucine (I)			Valine (V)

Sum of Absolute Deviation from Amino Acid Occurrence Frequencies

Aliphatic Index

Instability Index

Secondary Structure features

% Number of Residues in Helices	% Number of Residues in Strands	% Number of Residues in Coils

Structural Difficulty(SD) index

Role(s)

Stimulates increases in peripheral microtubule dynamics and may increase the motility of the infected cells, contributing to cell-to-cell spread of the virus. Seems to inhibit the signaling via the GTPase RHOA and DIAPH1/mDia (By similarity).

EC

Not Available

Predicted Functions

PANDA BPO	PANDA CCO	PANDA MFO	LocTree3	InterProScan
--	--	--	--	--

Subcellular Location

Not Available

Domain(s)

Not Available

Motif(s)

Not Available

Methods of 3D structure generation

Predicted/Modelled

Experimetally known structure

Not Available

Active Site(s)

Not Available

Predicted 3D Structures

Protein couldn't be modeled using I-Tasser and Raptor X because of length constraints of the software.

Experimentally known Ligand(s)

Not Available

Virtually Screened Ligands

Virtual screening has been performed using RASPD

						Million Molecules

					
Best 20 Hit molecules 
Not Available