Reviewed
Homo Sapiens (Human) [TaxID: 9606]
A10L[Gene ID: 1486485 ]
♦Major core protein 4a precursor (p4a) (Virion core protein 4a precursor) [Cleaved into: Core protein 4a (62 kDa peptide)
♦ 23 kDa protein (23K)]
♦ 23 kDa protein (23K)]
Variola Virus (isolate Human/India/Ind3/1967) (VARV) (Smallpox Virus)
Viruses> DsDNA Viruses> No RNA Stage> Poxviridae> Chordopoxvirinae> Orthopoxvirus> Variola Virus> Variola Virus (isolate Human/India/Ind3/1967) (VARV) (Smallpox Virus)
Various pathway(s) in which protein is involved
Not Available
MMPIKSIVTLDQLEDSEYLFRIVSTVLPHLCLDYKVCDQLKTTFVHPFDVFLNNSLGSVTKQDELQAAISKLGINYLIDTTSRELKLFNVTLNAGNIDII
NTPINISSETNPIINTHSFYDLPPFTQHLLNIRLTDTEYRARFIGGYIKPDGSDSMDVLAEKKYPDLNFDNTYLFNILYKDVINAPIKEFKAKIVNGVLS
RQDFDNLIGVRQYITAQDQPRFDNTYAIADAARHYGVNLNTLPLPNVDLTTMPTYKHLIMYEQYFVDDYDRVPIYYNGNRVIFDDEIINFCISMRYQSLI
PRLVEFFPDIPVNNNIVLHTRDPQNAAVNVTVGLPNMQFVDINRNNKFFINFFNLLAKEQRSTAIKVTKSMFWDGMDYEEYKSKNLQDMMFINSTCYVFG
LYNHNNTTYCSILSDIISAEKTPIRVCLLPRVVGGKTVTDLISETLKSISSMTIREFPKKDKSSIMHIGLSETGFMRFFQLLRLMADKPHETAIKEVVMA
YVGIKLGDKGSPYYIRKESYQDFIYLLFASMGFKVTTRRSIMGSNNISIISIRPRVTKQYIVTTLMKTSCSKNEAEKLITSAFDLLNFMVSVSDFRDYQS
YRQYRNYCPRYFYAGSPEGEETIICDSEPISILDRIDTRGIFSAYTINEMMDTDIFSPENKAFKNNLSRFIESGDITGEDIFCAMPYNILDRIITNAGTC
TVSIGDMLDNITTQSDCNMTNEITDMINASLKNTISKDNNMLVSQALDSVANHSKQKIGDLRQSSCKMALLFKNLATSIYTIERIFNAKVGDDVKASMLE
KYKVFTDISMSLYKDLIAMENLKAMLYIIRRSGCRIDDAQITTDDLVKSYSLIRPKILSMINYYNEMSRGYFEHMKKNLNMTDGDSVSFDDE
NTPINISSETNPIINTHSFYDLPPFTQHLLNIRLTDTEYRARFIGGYIKPDGSDSMDVLAEKKYPDLNFDNTYLFNILYKDVINAPIKEFKAKIVNGVLS
RQDFDNLIGVRQYITAQDQPRFDNTYAIADAARHYGVNLNTLPLPNVDLTTMPTYKHLIMYEQYFVDDYDRVPIYYNGNRVIFDDEIINFCISMRYQSLI
PRLVEFFPDIPVNNNIVLHTRDPQNAAVNVTVGLPNMQFVDINRNNKFFINFFNLLAKEQRSTAIKVTKSMFWDGMDYEEYKSKNLQDMMFINSTCYVFG
LYNHNNTTYCSILSDIISAEKTPIRVCLLPRVVGGKTVTDLISETLKSISSMTIREFPKKDKSSIMHIGLSETGFMRFFQLLRLMADKPHETAIKEVVMA
YVGIKLGDKGSPYYIRKESYQDFIYLLFASMGFKVTTRRSIMGSNNISIISIRPRVTKQYIVTTLMKTSCSKNEAEKLITSAFDLLNFMVSVSDFRDYQS
YRQYRNYCPRYFYAGSPEGEETIICDSEPISILDRIDTRGIFSAYTINEMMDTDIFSPENKAFKNNLSRFIESGDITGEDIFCAMPYNILDRIITNAGTC
TVSIGDMLDNITTQSDCNMTNEITDMINASLKNTISKDNNMLVSQALDSVANHSKQKIGDLRQSSCKMALLFKNLATSIYTIERIFNAKVGDDVKASMLE
KYKVFTDISMSLYKDLIAMENLKAMLYIIRRSGCRIDDAQITTDDLVKSYSLIRPKILSMINYYNEMSRGYFEHMKKNLNMTDGDSVSFDDE
892
Not Available
Not Available
01-02-1994
Inferred from homology
| Amino Acid | Count | % Frequency | Amino Acid | Count | % Frequency |
|---|---|---|---|---|---|
| Alanine (A) | Leucine (L) | ||||
| Arginine (R) | Lysine (K) | ||||
| Asparagine (N) | Methionine (M) | ||||
| Aspartic Acid (D) | Phenylalanine (F) | ||||
| Cysteine (C) | Proline (P) | ||||
| Glutamine (Q) | Serine (S) | ||||
| Glutamic Acid (E) | Threonine (T) | ||||
| Glycine (G) | Tryptophan (W) | ||||
| Histidine (H) | Tyrosine (Y) | ||||
| Isoleucine (I) | Valine (V) |
| % Number of Residues in Helices | % Number of Residues in Strands | % Number of Residues in Coils |
|---|---|---|
Core protein 4a is the most abundant virion protein. Major component of the virion core that undergoes proteolytic processing during the immature virion (IV) to mature virion (MV) transition (By similarity).
Not Available
Core protein 4a: Virion . Note=Probably localizes to the virion core wall. .
Not Available
Not Available
Predicted/Modelled
Not Available
Not Available
Protein couldn't be modeled using I-Tasser and Raptor X because of length constraints of the software.
Not Available
- Million Molecules
Best 20 Hit molecules
Not Available