Results | viHumans

UniProt ID

P32995

Status

Reviewed

Host

Homo Sapiens (Human) [TaxID: 9606]

Gene Name

G5R[Gene ID: 1486433 ]

Protein Name

Putative nuclease G5 (EC 3.1.-.-)

Organism Name

Variola Virus (isolate Human/India/Ind3/1967) (VARV) (Smallpox Virus)

Taxonomic Lineage

Viruses> DsDNA Viruses> No RNA Stage> Poxviridae> Chordopoxvirinae> Orthopoxvirus> Variola Virus> Variola Virus (isolate Human/India/Ind3/1967) (VARV) (Smallpox Virus)

RefSeq

NC_001611.1 ; X69198.1

PubMed ID

8109158 ; 8383392 ; 8384129 ; 8264798

Pathways Involved

Various pathway(s) in which protein is involved

KEGG

vg:1486433

Reactome

Not Available

Sequence

							MGIKNLKSLLLENKSLTILDDNLYKVYNGIFVDTMSIYIAVANCVRNLEELTTVFIKYVNGWVKKGGHVTLFIDRGSIKIKQNVRDKRRKYSKSTKDRKM
LELEKCTSKIQNVTGFMEEEIKAEIQLKIDKLTFQIYLSDSDNIKISLNEILTHFNNNENVTLFYCDERDAEFVMCLEAKTYFFTTGEWPLIISTDQDTM
LFASVDNHPKMIKNLTQLFKFVPSAEDNYLAKLTALVNGCDFFPGLYGASITPTNLNKIQLFSDFTINNIVTSLAIKNYYRKTNSTVDVRNIVTFINDYA
NLDDVYSYIPPCQCTVQEFIFSALDEKWNDFKSSYLETVPLPCQLMYALEPRKEIDVSEVKTLSSYIDFENTKSDIDVIKSISSIFGYSNENCNTIVFGI
YKDNLLLSINSSFYFNNSLLITNTKSDNIINIGY
						

Length

434

Alternate Sequence

Not Available

Non-standard residue

Not Available

Date of last Sequence modification

01-10-1993

Protein Existence

Evidence at transcript level

Amino Acid composition

Amino Acid	Count	% Frequency	Amino Acid	Count	% Frequency
Alanine (A)			Leucine (L)
Arginine (R)			Lysine (K)
Asparagine (N)			Methionine (M)
Aspartic Acid (D)			Phenylalanine (F)
Cysteine (C)			Proline (P)
Glutamine (Q)			Serine (S)
Glutamic Acid (E)			Threonine (T)
Glycine (G)			Tryptophan (W)
Histidine (H)			Tyrosine (Y)
Isoleucine (I)			Valine (V)

Sum of Absolute Deviation from Amino Acid Occurrence Frequencies

Aliphatic Index

Instability Index

Secondary Structure features

% Number of Residues in Helices	% Number of Residues in Strands	% Number of Residues in Coils

Structural Difficulty(SD) index

Role(s)

Putative nuclease that seems to be required for double-strand break repair, homologous recombination, and production of full-length viral genomic DNA.

EC

3.1.-.-

Experimentally known GO terms

GO:0004518 ; GO:0006281 ; GO:0019012 ; GO:0046872

Subcellular Location

Virion . Note=Present in the virion core. .

Domain(s)

Not Available

Motif(s)

Not Available

Methods of 3D structure generation

Predicted/Modelled

Experimetally known structure

Not Available

Active Site(s)

Not Available

Predicted 3D Structures

Protein couldn't be modeled using I-Tasser and Raptor X because of length constraints of the software.

Experimentally known Ligand(s)

Not Available

Virtually Screened Ligands

Virtual screening has been performed using RASPD

						Million Molecules

					
Best 20 Hit molecules 
Not Available