Results | viHumans

UniProt ID

P28282

Status

Reviewed

Host

Homo Sapiens (Human) [TaxID: 9606]

Gene Name

UL56[Gene ID: 1487345 ]

Protein Name

Protein UL56

Organism Name

Human Herpesvirus 2 (strain HG52) (HHV-2) (Human Herpes Simplex Virus 2)

Taxonomic Lineage

Viruses> DsDNA Viruses> No RNA Stage> Herpesvirales> Herpesviridae> Alphaherpesvirinae> Simplexvirus> Human Herpesvirus 2 (HHV-2) (Human Herpes Simplex Virus 2)> Human Herpesvirus 2 (strain HG52) (HHV-2) (Human Herpes Simplex Virus 2)

RefSeq

Not Available

PubMed ID

1662697 ; 9499055 ; 18353951 ; 19835589 ; 20682038

Pathways Involved

Various pathway(s) in which protein is involved

KEGG

vg:1487345

Reactome

Not Available

Sequence

							MALGAGHAHACRDDGDDSVIDAPPPYESVAGASAGQFVVIDIDTPTDSPPPYSAGTSPVGLVSPASSGDGEVCERGRSRRAAWRAARRARRRAERRARRR
SFGPGGLFVETPLFLPETMIGAHPGVGGDLPSGLPTYAEATSDRPPTYAMVMAACPTEPPGGSVGPADQPRVQSSRTWRPPLVNSRELYRAQRAARCASS
SDTPQAPGWCGGTCRHAVFGVVAVVVVIILAFLWR
						

Length

235

Alternate Sequence

Not Available

Non-standard residue

Not Available

Date of last Sequence modification

01-12-1992

Protein Existence

Evidence at protein level

Amino Acid composition

Amino Acid	Count	% Frequency	Amino Acid	Count	% Frequency
Alanine (A)			Leucine (L)
Arginine (R)			Lysine (K)
Asparagine (N)			Methionine (M)
Aspartic Acid (D)			Phenylalanine (F)
Cysteine (C)			Proline (P)
Glutamine (Q)			Serine (S)
Glutamic Acid (E)			Threonine (T)
Glycine (G)			Tryptophan (W)
Histidine (H)			Tyrosine (Y)
Isoleucine (I)			Valine (V)

Sum of Absolute Deviation from Amino Acid Occurrence Frequencies

Aliphatic Index

Instability Index

Secondary Structure features

% Number of Residues in Helices	% Number of Residues in Strands	% Number of Residues in Coils

Structural Difficulty(SD) index

Role(s)

Plays a role in the transport and release of virions form the host cytoplasm to the extracellular space. Relocalizes host NEDD4, a cytosolic E3 ligase, to cytoplasmic vesicles.

EC

Not Available

Experimentally known GO terms

GO:0016020 ; GO:0030430 ; GO:0033644

Subcellular Location

♦ Host membrane
♦ Single-pass membrane protein . Host cytoplasm , . Note=If expressed alone, is predominantly present in host trans-Golgi network (TGN) and partially in Golgi complex and early endosomes. .

Domain(s)

Not Available

Motif(s)

Not Available

Methods of 3D structure generation

Predicted/Modelled

Experimetally known structure

Not Available

Active Site(s)

Not Available

Predicted 3D Structures

Protein couldn't be modeled using I-Tasser and Raptor X because of length constraints of the software.

Experimentally known Ligand(s)

Not Available

Virtually Screened Ligands

Virtual screening has been performed using RASPD

						Million Molecules

					
Best 20 Hit molecules 
Not Available