Results | viHumans

UniProt ID

P27153

Status

Reviewed

Host

Homo Sapiens (Human) [TaxID: 9606]; Ixodida (ticks) [TaxID: 6935]

Gene Name

P2

Protein Name

RNA-directed RNA polymerase catalytic subunit (EC 2.7.7.48) (RNA-directed RNA polymerase subunit P2)

Organism Name

Dhori Virus (strain Indian/1313/61) (Dho)

Taxonomic Lineage

Viruses> SsRNA Viruses> SsRNA Negative-strand Viruses> Orthomyxoviridae> Thogotovirus> Dhori Thogotovirus> Dhori Virus (strain Indian/1313/61) (Dho)

RefSeq

NC_034261.1 ; GU969312.1 ; NC_034254.1 ; GU969313.1 ; NC_034255.1 ; GU969308.1 ; NC_034262.1 ;
GU969308.1 ; NC_034256.1 ; GU969312.1 ; NC_034263.1 ; GU969311.1

PubMed ID

2024457

Pathways Involved

Various pathway(s) in which protein is involved

KEGG

Not Available

Reactome

Not Available

Sequence

							MNLFSPRTGLSPTETQELLYAYTGPAPVAYGTRTRAVLENVLRPYKYFYKEENVPQALHIKTGQKGPEEISTTSPSSGFHRDSVILLSRELKAKYPEAFE
RLKAWIDCELLEMEYAELSKGRQTLSFLRNRNQPAPIALEETIEYLQQNLGRPIGQSMLSYLRAVMEVLAMPKTTFTYEVATNLARFDFEEYDDGETGPL
MMHFEKEKKKITITITQAELWEKTCTLGTMWKHLERGRLNRRTIATPSMLARGFVKIVEDAARVLLECLPSSGVPVGGEEKLAKLSSKLEAVSEVTGELS
GDQEKFNECLDPDAMRLMWTVFLEDYPQWVKELFNIPFLIFKAKIADIGEGLTYQKEGVVRVFPFGEMPSEFDELLPNAIKDKEGKIVGIRCTLGMFMGM
FNLSSTLLALIAADRSEITGDHVESSDDFIHFFKAKSYDDMFKQAELLRWSLKLVGINMSPSKCILISPAGIGEFNSKYHHRDFVGNVATDLPSLVPGGK
NPSSDLAMGLNVIRHSINTNQMNFISGDLALRIFTKAYRHSYMAEGITRRTKFLEAFKKDPVLLNQGAPTVHSVSTLHLDEVCLRYQMHLLGEEELRRIM
NPSNPITARTEEVVSFRPEGKLPMILEDNSVGSCFKYTFTRNRTVTDKPHRVLLEKEQQYQKITSFVEECFPELTIGNTTMPGTVKQACKRRLEYIIEQS
DLPTEQKRALLEEMDS
						

Length

716

Alternate Sequence

Not Available

Non-standard residue

Not Available

Date of last Sequence modification

01-08-1992

Protein Existence

Inferred from homology

Amino Acid composition

Amino Acid	Count	% Frequency	Amino Acid	Count	% Frequency
Alanine (A)			Leucine (L)
Arginine (R)			Lysine (K)
Asparagine (N)			Methionine (M)
Aspartic Acid (D)			Phenylalanine (F)
Cysteine (C)			Proline (P)
Glutamine (Q)			Serine (S)
Glutamic Acid (E)			Threonine (T)
Glycine (G)			Tryptophan (W)
Histidine (H)			Tyrosine (Y)
Isoleucine (I)			Valine (V)

Sum of Absolute Deviation from Amino Acid Occurrence Frequencies

Aliphatic Index

Instability Index

Secondary Structure features

% Number of Residues in Helices	% Number of Residues in Strands	% Number of Residues in Coils

Structural Difficulty(SD) index

Role(s)

Not Available

EC

2.7.7.48

Experimentally known GO terms

GO:0000166 ; GO:0003723 ; GO:0003968 ; GO:0039694

Subcellular Location

Not Available

Domain(s)

DOMAIN 286 465 RdRp catalytic.

Motif(s)

Not Available

Methods of 3D structure generation

Predicted/Modelled

Experimetally known structure

Not Available

Active Site(s)

Not Available

Predicted 3D Structures

Protein couldn't be modeled using I-Tasser and Raptor X because of length constraints of the software.

Experimentally known Ligand(s)

Not Available

Virtually Screened Ligands

Virtual screening has been performed using RASPD

						Million Molecules

					
Best 20 Hit molecules 
Not Available