Results | viHumans

UniProt ID

P26590

Status

Reviewed

Host

Homo Sapiens (Human) [TaxID: 9606]

Gene Name

N NP

Protein Name

Nucleoprotein (Nucleocapsid protein) (NP) (Protein N)

Organism Name

Human Parainfluenza 1 Virus (strain Washington/1957) (HPIV-1)

Taxonomic Lineage

Viruses> SsRNA Viruses> SsRNA Negative-strand Viruses> Mononegavirales> Paramyxoviridae> Respirovirus> Human Respirovirus 1> Human Parainfluenza 1 Virus (strain Washington/1957) (HPIV-1)

RefSeq

NC_003461.1 ; AF457102.1

PubMed ID

1707951

Pathways Involved

Various pathway(s) in which protein is involved

KEGG

Not Available

Reactome

Not Available

Sequence

							MAGLLSTFDTFSSRRSESINKSGGGAIIPGQRSTVSVFILGPSVTDDADKLLIATTFLAHSLDTDKQHSQRGGFLVSLLAMAIRSPELYLTTNGVNADVK
YVIYNIERDPKRTKTDGFIVKTRDMEYERTTEWLFGPMINKNPLFQGQRENADLEALLQTYGYPACLGAIIVQVWIVLVKAITSSAGLRKGFFNRLEAFR
QDGTVKSALVFTGDTVEGIGAVMRSQQSLVSLMVETLVTMNTSRSDLTTLEKNIQIVGNYIRDAGLASFMNTIKYGVETKMAALTLSNLRPDINKLRSLV
DIYLSKGARAPFICILRDPVHGEFAPGNYPALWSYAMGVAVVQNKAMQQYVTGRTYLDMEMFLLGQAVAKDADSKISSALEEELNVTDTAKERLRHHLTN
LSGGDGAYHKPTGGGAIEVAIDHTDITFGAEDTADRDNKNWTNNSNERWSNHSINNHTITISGAEQLEEETNDEDITDIENKIARRLADKKQRLSQANNK
QDANSDADYENDDDATAAAGIGGI
						

Length

524

Alternate Sequence

Not Available

Non-standard residue

Not Available

Date of last Sequence modification

01-08-1992

Protein Existence

Evidence at protein level

Amino Acid composition

Amino Acid	Count	% Frequency	Amino Acid	Count	% Frequency
Alanine (A)			Leucine (L)
Arginine (R)			Lysine (K)
Asparagine (N)			Methionine (M)
Aspartic Acid (D)			Phenylalanine (F)
Cysteine (C)			Proline (P)
Glutamine (Q)			Serine (S)
Glutamic Acid (E)			Threonine (T)
Glycine (G)			Tryptophan (W)
Histidine (H)			Tyrosine (Y)
Isoleucine (I)			Valine (V)

Sum of Absolute Deviation from Amino Acid Occurrence Frequencies

Aliphatic Index

Instability Index

Secondary Structure features

% Number of Residues in Helices	% Number of Residues in Strands	% Number of Residues in Coils

Structural Difficulty(SD) index

Role(s)

Encapsidates the genome in a ratio of 1 N per 6 ribonucleotides, protecting it from nucleases. The nucleocapsid (NC) has a helical structure. The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication. During replication, encapsidation by N is coupled to RNA synthesis and all replicative products are resistant to nucleases (By similarity).

EC

Not Available

Experimentally known GO terms

GO:0003723 ; GO:0005198 ; GO:0019013 ; GO:0019029 ; GO:0030430

Subcellular Location

Virion . Host cytoplasm.

Domain(s)

Not Available

Motif(s)

Not Available

Methods of 3D structure generation

X-ray crystallography (1)

Experimetally known structure

2CII

Active Site(s)

Not Available

Predicted 3D Structures

Protein couldn't be modeled using I-Tasser and Raptor X because of length constraints of the software.

Experimentally known Ligand(s)

Not Available

Virtually Screened Ligands

Virtual screening has been performed using RASPD

						Million Molecules

					
Best 20 Hit molecules 
Not Available