Reviewed
Homo Sapiens (Human) [TaxID: 9606]
L3[Gene ID: 1460858 ]
Hexon protein (CP-H) (Protein II)
Human Adenovirus A Serotype 12 (HAdV-12) (Human Adenovirus 12)
Viruses> DsDNA Viruses> No RNA Stage> Adenoviridae> Mastadenovirus> Human Mastadenovirus A> Human Adenovirus A Serotype 12 (HAdV-12) (Human Adenovirus 12)
Various pathway(s) in which protein is involved
Not Available
Not Available
MATPSMMPQWSYMHIAGQDASEYLSPGLVQFARATDTYFTLGNKFRNPTVAPTHDVTTDRSQRLTLRFVPVDREDTTYSYKARFTLAVGDNRVLDMASSY
FDIRGVLDRGPSFKPYSGTAYNSLAPKGAPNASQWSDNAKLNTFAQAPYLSDTITAADGIKVGTDTAQAGAAVYANKTYQPEPQVGPSEWNTSIENVKAG
GRALKQTTAMQPCYGSYARPTNEHGGQSKDDNIELKFFDSANNAANTAQVVFYTEDVNLEMPDTHLVFKPTVTNGTIASESLLGQQAAPNRANYIAFRDN
FIGLMYYNSTGNMGVLAGQASQLNAVVDLQDRNTELSYQLMLDALGDRTRYFSLWNSAVDSYDPDVRVIENHGVEDELPNYCFPLSAVGEIKNYKGIKPD
NGGGGGWTADNTVSEANHIGIGNIAAMEINLQANLWRSFLYSNVGLYLPDDLKYTPGNIKLPDNKNTYEYMNGRVTAPGLVDTYVNIGARWSPDVMDNVN
PFNHHRNAGLRYRSMLLGNGRFVPFHIQVPQKFFAIRNLLLLPGSYTYEWNFRKDVNMILQSTLGNDLRVDGASVRFDNIALYANFFPMAHNTASTLEAM
LRNDTNDQSFNDYLCAANMLYPIPANATSVPISIPSRNWAAFRGWSFTRLKTKETPSLGSGFDPYFVYSGTIPYLDGTFYLNHTFKKVSIMFDSSVSWPG
NDRLLTPNEFEIKRSVDGEGYNVAQCNMTKDWFLIQMLSHYNIGYQGFYIPESYKDRMYSFFRNFQPMSRQVVDTTEYKNYKKVTVEFQHNNSGFVGYLG
PTMREGQAYPANYPYPLIGQTAVESITQKKFLCDRVMWRIPFSSNFMSMGALTDLGQNMLYANSAHALDMTFEVDPMDEPTLLYVLFEVFDVVRIHQPHR
GVIEAVYLRTPFSAGNATT
FDIRGVLDRGPSFKPYSGTAYNSLAPKGAPNASQWSDNAKLNTFAQAPYLSDTITAADGIKVGTDTAQAGAAVYANKTYQPEPQVGPSEWNTSIENVKAG
GRALKQTTAMQPCYGSYARPTNEHGGQSKDDNIELKFFDSANNAANTAQVVFYTEDVNLEMPDTHLVFKPTVTNGTIASESLLGQQAAPNRANYIAFRDN
FIGLMYYNSTGNMGVLAGQASQLNAVVDLQDRNTELSYQLMLDALGDRTRYFSLWNSAVDSYDPDVRVIENHGVEDELPNYCFPLSAVGEIKNYKGIKPD
NGGGGGWTADNTVSEANHIGIGNIAAMEINLQANLWRSFLYSNVGLYLPDDLKYTPGNIKLPDNKNTYEYMNGRVTAPGLVDTYVNIGARWSPDVMDNVN
PFNHHRNAGLRYRSMLLGNGRFVPFHIQVPQKFFAIRNLLLLPGSYTYEWNFRKDVNMILQSTLGNDLRVDGASVRFDNIALYANFFPMAHNTASTLEAM
LRNDTNDQSFNDYLCAANMLYPIPANATSVPISIPSRNWAAFRGWSFTRLKTKETPSLGSGFDPYFVYSGTIPYLDGTFYLNHTFKKVSIMFDSSVSWPG
NDRLLTPNEFEIKRSVDGEGYNVAQCNMTKDWFLIQMLSHYNIGYQGFYIPESYKDRMYSFFRNFQPMSRQVVDTTEYKNYKKVTVEFQHNNSGFVGYLG
PTMREGQAYPANYPYPLIGQTAVESITQKKFLCDRVMWRIPFSSNFMSMGALTDLGQNMLYANSAHALDMTFEVDPMDEPTLLYVLFEVFDVVRIHQPHR
GVIEAVYLRTPFSAGNATT
919
Not Available
Not Available
01-06-1994
Inferred from homology
| Amino Acid | Count | % Frequency | Amino Acid | Count | % Frequency |
|---|---|---|---|---|---|
| Alanine (A) | Leucine (L) | ||||
| Arginine (R) | Lysine (K) | ||||
| Asparagine (N) | Methionine (M) | ||||
| Aspartic Acid (D) | Phenylalanine (F) | ||||
| Cysteine (C) | Proline (P) | ||||
| Glutamine (Q) | Serine (S) | ||||
| Glutamic Acid (E) | Threonine (T) | ||||
| Glycine (G) | Tryptophan (W) | ||||
| Histidine (H) | Tyrosine (Y) | ||||
| Isoleucine (I) | Valine (V) |
| % Number of Residues in Helices | % Number of Residues in Strands | % Number of Residues in Coils |
|---|---|---|
Major capsid protein that self-associates to form 240 hexon trimers, each in the shape of a hexagon, building most of the pseudo T=25 capsid. Assembled into trimeric units with the help of the chaperone shutoff protein. Transported by pre-protein VI to the nucleus where it associates with other structural proteins to form an empty capsid. Might be involved, through its interaction with host dyneins, in the intracellular microtubule-dependent transport of incoming viral capsid to the nucleus.
Not Available
Virion . Host nucleus . Note=Forms the capsid icosahedric shell. Present in 720 copies per virion, assembled in 240 trimers. .
Not Available
Not Available
Predicted/Modelled
Not Available
Not Available
Protein couldn't be modeled using I-Tasser and Raptor X because of length constraints of the software.
Not Available
- Million Molecules
Best 20 Hit molecules
Not Available