Results | viHumans

UniProt ID

P16721

Status

Reviewed

Host

Homo Sapiens (Human) [TaxID: 9606]

Gene Name

UL11

Protein Name

Protein UL11

Organism Name

Human Cytomegalovirus (strain AD169) (HHV-5) (Human Herpesvirus 5)

Taxonomic Lineage

Viruses> DsDNA Viruses> No RNA Stage> Herpesvirales> Herpesviridae> Betaherpesvirinae> Cytomegalovirus> Human Cytomegalovirus (HHV-5) (Human Herpesvirus 5)> Human Cytomegalovirus (strain AD169) (HHV-5) (Human Herpesvirus 5)

RefSeq

Not Available

PubMed ID

2161319 ; 9267452 ; 12533697

Pathways Involved

Various pathway(s) in which protein is involved

KEGG

Not Available

Reactome

Not Available

Sequence

							MLLRYITFHREKVLYLAIACFFGIYISFHDACILVPAKVGTNVTLNAVHVHDGDYVYWSFGGGGANRLMCRYTPRLDEIHKNTNRSFSCLTNHSLLLINV
TEEYTDYYRTMTTFVHQSHNWHNHGNKWTLDTCYYVYVTQNGTLPTTTTKKPTTTTRTTTTTTTKKTTTTSTTTTTTTTKKTTTSTTHHRHSNPKESTTP
KTHVELHVGLGATAAETPLQPSPQYQHVATHALWVLAVVIVIIIIIIFYFRIPQKLWLLWQHDKHGIVLIPQTDL
						

Length

275

Alternate Sequence

Not Available

Non-standard residue

Not Available

Date of last Sequence modification

01-08-1990

Protein Existence

Evidence at transcript level

Amino Acid composition

Amino Acid	Count	% Frequency	Amino Acid	Count	% Frequency
Alanine (A)			Leucine (L)
Arginine (R)			Lysine (K)
Asparagine (N)			Methionine (M)
Aspartic Acid (D)			Phenylalanine (F)
Cysteine (C)			Proline (P)
Glutamine (Q)			Serine (S)
Glutamic Acid (E)			Threonine (T)
Glycine (G)			Tryptophan (W)
Histidine (H)			Tyrosine (Y)
Isoleucine (I)			Valine (V)

Sum of Absolute Deviation from Amino Acid Occurrence Frequencies

Aliphatic Index

Instability Index

Secondary Structure features

% Number of Residues in Helices	% Number of Residues in Strands	% Number of Residues in Coils

Structural Difficulty(SD) index

Role(s)

Plays a role in the modulation of host immune response by modulating T-cell function. Interacts with host PTPRC/CD45 and thereby reduces host TCR signaling and T-cell proliferation.

EC

Not Available

Experimentally known GO terms

GO:0016021 ; GO:0020002 ; GO:0044165

Subcellular Location

♦ Host cell membrane
♦ Single-pass type I membrane protein SWB9. Host endoplasmic reticulum SWB9. Note=Localizes to the host cell membrane when highly glycosylated while less glycosylated forms are found on the endoplasmic reticulum. SWB9.

Domain(s)

Not Available

Motif(s)

Not Available

Methods of 3D structure generation

Predicted/Modelled

Experimetally known structure

Not Available

Active Site(s)

Not Available

Predicted 3D Structures

Protein couldn't be modeled using I-Tasser and Raptor X because of length constraints of the software.

Experimentally known Ligand(s)

Not Available

Virtually Screened Ligands

Virtual screening has been performed using RASPD

						Million Molecules

					
Best 20 Hit molecules 
Not Available