Results | viHumans

UniProt ID

P16629

Status

Reviewed

Host

Canis Lupus Familiaris (Dog) (Canis Familiaris) [TaxID: 9615]; Homo Sapiens (Human) [TaxID: 9606]

Gene Name

M[Gene ID: 3160802 ]

Protein Name

Matrix protein (Membrane protein)

Organism Name

Parainfluenza Virus 5 (strain W3) (PIV5) (Simian Virus 5)

Taxonomic Lineage

Viruses> SsRNA Viruses> SsRNA Negative-strand Viruses> Mononegavirales> Paramyxoviridae> Rubulavirus> Mammalian Rubulavirus 5> Parainfluenza Virus 5 (strain W3) (PIV5) (Simian Virus 5)

RefSeq

Not Available

PubMed ID

2330672 ; 15709019

Pathways Involved

Various pathway(s) in which protein is involved

KEGG

vg:3160802

Reactome

Not Available

Sequence

							MPSISIPADPTNPRQSIKAFPIVINSDGGEKGRLVKQLRTTYLNDLDTHEPLVTFINTYGFIYEQDRGNTIVGEDQLGKKREAVTAAMVTLGCGPNLPSL
GNVLGQLREFQVTVRKTSSKAEEMVFEIVKYPRIFRGHTLIQKGLVCVSAEKFVKSPGKIQSGMDYLFIPTFLSVTYCPAAIKFQVPGPMLKMRSRYTQS
LQLELMIRILCKPDSPLMKVHTPDKEGRGCLVSVWLHVCNIFKSGNKNGSEWQEYWMRKCANMQLEVSIADMWGPTIIIHARGHIPKSAKLFFGKGGWSC
HPLHEVVPSVTKTLWSVGCEITKAKAIIQESSISLLVETTDIISPKVKISSKHRRFVKSNWGLFKKTKSLPNLTELE
						

Length

377

Alternate Sequence

Not Available

Non-standard residue

Not Available

Date of last Sequence modification

01-08-1990

Protein Existence

Inferred from homology

Amino Acid composition

Amino Acid	Count	% Frequency	Amino Acid	Count	% Frequency
Alanine (A)			Leucine (L)
Arginine (R)			Lysine (K)
Asparagine (N)			Methionine (M)
Aspartic Acid (D)			Phenylalanine (F)
Cysteine (C)			Proline (P)
Glutamine (Q)			Serine (S)
Glutamic Acid (E)			Threonine (T)
Glycine (G)			Tryptophan (W)
Histidine (H)			Tyrosine (Y)
Isoleucine (I)			Valine (V)

Sum of Absolute Deviation from Amino Acid Occurrence Frequencies

Aliphatic Index

Instability Index

Secondary Structure features

% Number of Residues in Helices	% Number of Residues in Strands	% Number of Residues in Coils

Structural Difficulty(SD) index

Role(s)

The M protein has a crucial role in virus assembly and interacts with the RNP complex as well as with the viral membrane.

EC

Not Available

Experimentally known GO terms

GO:0019031 ; GO:0039660 ; GO:0039702 ; GO:0046761

Subcellular Location

Virion .

Domain(s)

Not Available

Motif(s)

MOTIF 20 23 FPIV motif.

Methods of 3D structure generation

Predicted/Modelled

Experimetally known structure

Not Available

Active Site(s)

Not Available

Predicted 3D Structures

Protein couldn't be modeled using I-Tasser and Raptor X because of length constraints of the software.

Experimentally known Ligand(s)

Not Available

Virtually Screened Ligands

Virtual screening has been performed using RASPD

						Million Molecules

					
Best 20 Hit molecules 
Not Available