Results | viHumans

UniProt ID

P16495

Status

Reviewed

Host

Aedes Aegypti (Yellowfever Mosquito) (Culex Aegypti) [TaxID: 7159]; Homo Sapiens (Human) [TaxID: 9606]

Gene Name

N[Gene ID: 2648217 ]

Protein Name

Nucleoprotein (Nucleocapsid protein) (Protein N)

Organism Name

Bunyamwera Virus (BUNV)

Taxonomic Lineage

Viruses> SsRNA Viruses> SsRNA Negative-strand Viruses> Bunyavirales> Peribunyaviridae> Orthobunyavirus> Bunyamwera Orthobunyavirus> Bunyamwera Virus (BUNV)

RefSeq

NC_001925.1 ; D00353.1 ; NC_001926.1 ; D00353.1 ; NC_001927.1 ; M11852.1

PubMed ID

2732714 ; 19193790

Pathways Involved

Various pathway(s) in which protein is involved

KEGG

vg:2648217

Reactome

Not Available

Sequence

							MIELEFHDVAANTSSTFDPEVAYANFKRVHTTGLSYDHIRIFYIKGREIKTSLAKRSEWEVTLNLGGWKITVYNTNFPGNRNNPVPDDGLTLHRLSGFLA
RYLLEKMLKVSEPEKLIIKSKIINPLAEKNGITWNDGEEVYLSFFPGSEMFLGTFRFYPLAIGIYKVQRKEMEPKYLEKTMRQRYMGLEAATWTVSKLTE
VQSALTVVSSLGWKKTNVSAAARDFLAKFGINM
						

Length

233

Alternate Sequence

Not Available

Non-standard residue

Not Available

Date of last Sequence modification

01-08-1990

Protein Existence

Evidence at protein level

Amino Acid composition

Amino Acid	Count	% Frequency	Amino Acid	Count	% Frequency
Alanine (A)			Leucine (L)
Arginine (R)			Lysine (K)
Asparagine (N)			Methionine (M)
Aspartic Acid (D)			Phenylalanine (F)
Cysteine (C)			Proline (P)
Glutamine (Q)			Serine (S)
Glutamic Acid (E)			Threonine (T)
Glycine (G)			Tryptophan (W)
Histidine (H)			Tyrosine (Y)
Isoleucine (I)			Valine (V)

Sum of Absolute Deviation from Amino Acid Occurrence Frequencies

Aliphatic Index

Instability Index

Secondary Structure features

% Number of Residues in Helices	% Number of Residues in Strands	% Number of Residues in Coils

Structural Difficulty(SD) index

Role(s)

Encapsidates the genome protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for transcription and replication. Seems to participate in the nuclear relocalization of host PABP1, thereby inhibiting host cellular translation.

EC

Not Available

Experimentally known GO terms

GO:0003723 ; GO:0019013 ; GO:0019029 ; GO:0039657

Subcellular Location

Virion. Note=Internal protein of virus particle.

Domain(s)

Not Available

Motif(s)

Not Available

Methods of 3D structure generation

X-ray crystallography (2)

Experimetally known structure

3ZLA 4IJS

Active Site(s)

Not Available

Predicted 3D Structures

Protein couldn't be modeled using I-Tasser and Raptor X because of length constraints of the software.

Experimentally known Ligand(s)

Not Available

Virtually Screened Ligands

Virtual screening has been performed using RASPD

						Million Molecules

					
Best 20 Hit molecules 
Not Available