Results | viHumans

UniProt ID

P12491

Status

Reviewed

Host

Homo Sapiens (Human) [TaxID: 9606]

Gene Name

Env

Protein Name

Truncated surface protein (SU) (Glycoprotein 120) (gp120)

Organism Name

Human Immunodeficiency Virus Type 1 Group M Subtype U (isolate Z3) (HIV-1)

Taxonomic Lineage

Viruses> Retro-transcribing Viruses> Retroviridae> Orthoretrovirinae> Lentivirus> Primate Lentivirus Group> Human Immunodeficiency Virus 1> HIV-1 Unknown Group> Human Immunodeficiency Virus Type 1 Group M Subtype U (isolate Z3) (HIV-1)

RefSeq

NC_001802.1 ; AF033819.3

PubMed ID

3014529

Pathways Involved

Various pathway(s) in which protein is involved

KEGG

Not Available

Reactome

R-HSA-5621480;

Sequence

							MRVKEIQRNYQHLWKWSLIILGMIMICKAIEKSWVTVYYGVPVWKDAETTLFCASDAKAYEKESHNVWATHACVPSDPSPQELVLGNVTENFNMWKNKMV
EQMHEDIISLWDQSLKPCVKLTFLCVTLNCIDVKNSTNNNTEEATITNCSFKVPTELKDKTETVHTLFYKLDVVPLNVTNNSSISSTYRLINCNTSTITQ
ACPKVSFEPIPIHYCAPAGFAILKCNDKKFNGTGPCKNVSTVQCTHGIRPVVSTQLLLNGSLSEEEVIIRSENITNNAKTIIVQLNETVKINCTRPGSDK
KIRQSIRIGPGKVFYAKGGITGQAHCNITDGEWRNTLQQVAIALRRQFNNKSIIFNSSSGGDIEITTHTFNCGGEFFYCNTSELFTGIWNGTWDKNCTST
ESNCTGNITLPCRIKQVVRTWQGVGQAMYAPPIEGTIRCSSNITGLLLTRDGGNGKCNSK
						

Length

460

Alternate Sequence

Not Available

Non-standard residue

Not Available

Date of last Sequence modification

01-10-1989

Protein Existence

Inferred from homology

Amino Acid composition

Amino Acid	Count	% Frequency	Amino Acid	Count	% Frequency
Alanine (A)			Leucine (L)
Arginine (R)			Lysine (K)
Asparagine (N)			Methionine (M)
Aspartic Acid (D)			Phenylalanine (F)
Cysteine (C)			Proline (P)
Glutamine (Q)			Serine (S)
Glutamic Acid (E)			Threonine (T)
Glycine (G)			Tryptophan (W)
Histidine (H)			Tyrosine (Y)
Isoleucine (I)			Valine (V)

Sum of Absolute Deviation from Amino Acid Occurrence Frequencies

Aliphatic Index

Instability Index

Secondary Structure features

% Number of Residues in Helices	% Number of Residues in Strands	% Number of Residues in Coils

Structural Difficulty(SD) index

Role(s)

Not Available

EC

Not Available

Experimentally known GO terms

GO:0002223 ; GO:0019031 ; GO:0019062 ; GO:0039654 ; GO:0055036 ;
GO:0075512

Subcellular Location

Virion membrane .

Domain(s)

Not Available

Motif(s)

Not Available

Methods of 3D structure generation

Predicted/Modelled

Experimetally known structure

Not Available

Active Site(s)

Not Available

Predicted 3D Structures

Protein couldn't be modeled using I-Tasser and Raptor X because of length constraints of the software.

Experimentally known Ligand(s)

Not Available

Virtually Screened Ligands

Virtual screening has been performed using RASPD

						Million Molecules

					
Best 20 Hit molecules 
Not Available