Results | viHumans

UniProt ID

P10205

Status

Reviewed

Host

Homo Sapiens (Human) [TaxID: 9606]

Gene Name

UL21[Gene ID: 2703372 ]

Protein Name

Tegument protein UL21

Organism Name

Human Herpesvirus 1 (strain 17) (HHV-1) (Human Herpes Simplex Virus 1)

Taxonomic Lineage

Viruses> DsDNA Viruses> No RNA Stage> Herpesvirales> Herpesviridae> Alphaherpesvirinae> Simplexvirus> Human Herpesvirus 1 (HHV-1) (Human Herpes Simplex Virus 1)> Human Herpesvirus 1 (strain 17) (HHV-1) (Human Herpes Simplex Virus 1)

RefSeq

Not Available

PubMed ID

2839594 ; 17218138 ; 11733033 ; 18596102 ; 20042500

Pathways Involved

Various pathway(s) in which protein is involved

KEGG

vg:2703372

Reactome

Not Available

Sequence

							MELSYATTMHYRDVVFYVTTDRNRAYFVCGGCVYSVGRPCASQPGEIAKFGLVVRGTGPDDRVVANYVRSELRQRGLQDVRPIGEDEVFLDSVCLLNPNV
SSELDVINTNDVEVLDECLAEYCTSLRTSPGVLISGLRVRAQDRIIELFEHPTIVNVSSHFVYTPSPYVFALAQAHLPRLPSSLEALVSGLFDGIPAPRQ
PLDAHNPRTDVVITGRRAPRPIAGSGAGSGGAGAKRATVSEFVQVKHIDRVGPAGVSPAPPPNNTDSSSLVPGAQDSAPPGPTLRELWWVFYAADRALEE
PRADSGLTREEVRAVRGFREQAWKLFGSAGAPRAFIGAALGLSPLQKLAVYYYIIHRERRLSPFPALVRLVGRYTQRHGLYVPRPDDPVLADAINGLFRD
ALAAGTTAEQLLMFDLLPPKDVPVGSDVQADSTALLRFIESQRLAVPGGVISPEHVAYLGAFLSVLYAGRGRMSAATHTARLTGVTSLVLAVGDVDRLSA
FDRGAAGAASRTRAAGYLDVLLTVRLARSQHGQSV
						

Length

535

Alternate Sequence

Not Available

Non-standard residue

Not Available

Date of last Sequence modification

01-07-1989

Protein Existence

Evidence at protein level

Amino Acid composition

Amino Acid	Count	% Frequency	Amino Acid	Count	% Frequency
Alanine (A)			Leucine (L)
Arginine (R)			Lysine (K)
Asparagine (N)			Methionine (M)
Aspartic Acid (D)			Phenylalanine (F)
Cysteine (C)			Proline (P)
Glutamine (Q)			Serine (S)
Glutamic Acid (E)			Threonine (T)
Glycine (G)			Tryptophan (W)
Histidine (H)			Tyrosine (Y)
Isoleucine (I)			Valine (V)

Sum of Absolute Deviation from Amino Acid Occurrence Frequencies

Aliphatic Index

Instability Index

Secondary Structure features

% Number of Residues in Helices	% Number of Residues in Strands	% Number of Residues in Coils

Structural Difficulty(SD) index

Role(s)

May participate in DNA packaging/capsid maturation events. Promotes efficient incorporation of tegument proteins UL46, UL49, and US3 into virions. May also play a role in capsid transport to the trans-Golgi network (TGN) (By similarity).

EC

Not Available

Experimentally known GO terms

GO:0019033 ; GO:0030430 ; GO:0042025

Subcellular Location

Virion tegument . Host cytoplasm . Host nucleus .

Domain(s)

Not Available

Motif(s)

Not Available

Methods of 3D structure generation

X-ray crystallography (2)

Experimetally known structure

4U4H 5ED7

Active Site(s)

Not Available

Predicted 3D Structures

Protein couldn't be modeled using I-Tasser and Raptor X because of length constraints of the software.

Experimentally known Ligand(s)

Not Available

Virtually Screened Ligands

Virtual screening has been performed using RASPD

						Million Molecules

					
Best 20 Hit molecules 
Not Available