Results | viHumans

UniProt ID

P0DOE5

Status

Reviewed

Host

Homo Sapiens (Human) [TaxID: 9606]

Gene Name

SH 1A

Protein Name

Small hydrophobic protein (Small protein 1A)

Organism Name

Human Respiratory Syncytial Virus A (strain A2)

Taxonomic Lineage

Viruses> SsRNA Viruses> SsRNA Negative-strand Viruses> Mononegavirales> Pneumoviridae> Orthopneumovirus> Human Respiratory Syncytial Virus> Human Respiratory Syncytial Virus A> Human Respiratory Syncytial Virus A (strain A2)

RefSeq

Not Available

PubMed ID

3879976 ; 7747420 ; 9035372 ; 2649692 ; 15105532 ; 15659757 ; 17494063 ; 18036342 ; 18369195

Pathways Involved

Various pathway(s) in which protein is involved

KEGG

Not Available

Reactome

Not Available

Sequence

							MENTSITIEFSSKFWPYFTLIHMITTIISLLIIISIMIAILNKLCEYNVFHNKTFELPRARVNT
						

Length

64

Alternate Sequence

VAR_SEQ 1 22 Missing (in isoform SHt)

Non-standard residue

Not Available

Date of last Sequence modification

12-04-2017

Protein Existence

Evidence at protein level

Amino Acid composition

Amino Acid	Count	% Frequency	Amino Acid	Count	% Frequency
Alanine (A)			Leucine (L)
Arginine (R)			Lysine (K)
Asparagine (N)			Methionine (M)
Aspartic Acid (D)			Phenylalanine (F)
Cysteine (C)			Proline (P)
Glutamine (Q)			Serine (S)
Glutamic Acid (E)			Threonine (T)
Glycine (G)			Tryptophan (W)
Histidine (H)			Tyrosine (Y)
Isoleucine (I)			Valine (V)

Sum of Absolute Deviation from Amino Acid Occurrence Frequencies

Aliphatic Index

Instability Index

Secondary Structure features

% Number of Residues in Helices	% Number of Residues in Strands	% Number of Residues in Coils

Structural Difficulty(SD) index

Role(s)

May form a proton-selective ion channel, playing a role in budding and /or during virus entry. May also play a role in counteracting host innate immunity.

EC

Not Available

Experimentally known GO terms

GO:0006811 ; GO:0016021 ; GO:0020002 ; GO:0042802 ; GO:0055036

Subcellular Location

♦ Virion membrane
♦ Single-pass type II membrane protein . Host cell membrane
♦ Single-pass type II membrane protein . Note=Present in very small amount in the virion. .

Domain(s)

Not Available

Motif(s)

Not Available

Methods of 3D structure generation

NMR spectroscopy (2)

Experimetally known structure

2NB7 2NB8

Active Site(s)

Not Available

Predicted 3D Structures

Protein couldn't be modeled using I-Tasser and Raptor X because of length constraints of the software.

Experimentally known Ligand(s)

Not Available

Virtually Screened Ligands

Virtual screening has been performed using RASPD

						Million Molecules

					
Best 20 Hit molecules 
Not Available