Results | viHumans

UniProt ID

P0CK59

Status

Reviewed

Host

Homo Sapiens (Human) [TaxID: 9606]

Gene Name

BALF1[Gene ID: 3783677 ]

Protein Name

Apoptosis regulator BALF1

Organism Name

Epstein-Barr Virus (strain GD1) (HHV-4) (Human Herpesvirus 4)

Taxonomic Lineage

Viruses> DsDNA Viruses> No RNA Stage> Herpesvirales> Herpesviridae> Gammaherpesvirinae> Lymphocryptovirus> Epstein-Barr Virus (strain GD1) (HHV-4) (Human Herpesvirus 4)

RefSeq

NC_007605.1 ; AJ507799.2

PubMed ID

16306603

Pathways Involved

Various pathway(s) in which protein is involved

KEGG

vg:3783677

Reactome

Not Available

Sequence

							MNLAIALDSPHPGLASYTILPRPFYHISLKPVSWPDETMRPAKSTDSVFVRTPVEAWVAPSPPDDKVAESSYLMFRAMYAVFTRDEKDLPLPALVLCRLI
KASLRKDRKLYAELACRTADIGGKDTHVRLIISVLRAVYNDHYDYWSRLRVVLCYTVVFAVRNYLDDHKSAAFVLGAIAHYLALYRRLWFARLGGMPRSL
RRQFPVTWALASLTDFLKSL
						

Length

220

Alternate Sequence

Not Available

Non-standard residue

Not Available

Date of last Sequence modification

21-03-2012

Protein Existence

Inferred from homology

Amino Acid composition

Amino Acid	Count	% Frequency	Amino Acid	Count	% Frequency
Alanine (A)			Leucine (L)
Arginine (R)			Lysine (K)
Asparagine (N)			Methionine (M)
Aspartic Acid (D)			Phenylalanine (F)
Cysteine (C)			Proline (P)
Glutamine (Q)			Serine (S)
Glutamic Acid (E)			Threonine (T)
Glycine (G)			Tryptophan (W)
Histidine (H)			Tyrosine (Y)
Isoleucine (I)			Valine (V)

Sum of Absolute Deviation from Amino Acid Occurrence Frequencies

Aliphatic Index

Instability Index

Secondary Structure features

% Number of Residues in Helices	% Number of Residues in Strands	% Number of Residues in Coils

Structural Difficulty(SD) index

Role(s)

May play a role in host B-cell survival by preventing host apoptosis. The survival of infected B-cells is a key step to induce host cell differentiation into memory cells, thereby assuring long term infection of the organism. May also play an active part in oncogenesis in Burkitt's lymphomy and nasopharyngeal carcinoma (By similarity).

EC

Not Available

Predicted Functions

PANDA BPO	PANDA CCO	PANDA MFO	LocTree3	InterProScan
--	--	--	--	--

Subcellular Location

Not Available

Domain(s)

Not Available

Motif(s)

Not Available

Methods of 3D structure generation

Predicted/Modelled

Experimetally known structure

Not Available

Active Site(s)

Not Available

Predicted 3D Structures

Protein couldn't be modeled using I-Tasser and Raptor X because of length constraints of the software.

Experimentally known Ligand(s)

Not Available

Virtually Screened Ligands

Virtual screening has been performed using RASPD

						Million Molecules

					
Best 20 Hit molecules 
Not Available