Reviewed
Homo Sapiens (Human) [TaxID: 9606]
ORF52
DNA helicase/primase complex-associated protein (HEPA) (Primase-associated factor)
Varicella-zoster Virus (strain Dumas) (HHV-3) (Human Herpesvirus 3)
Viruses> DsDNA Viruses> No RNA Stage> Herpesvirales> Herpesviridae> Alphaherpesvirinae> Varicellovirus> Human Herpesvirus 3 (HHV-3) (Varicella-zoster Virus)> Varicella-zoster Virus (strain Dumas) (HHV-3) (Human Herpesvirus 3)
Various pathway(s) in which protein is involved
Not Available
Not Available
MDATQITLVRESGHICAASIYTSWTQSGQLTQNGLSVLYYLLCKNSCGKYVPKFAEITVQQEDLCRYSRHGGSVSAATFASICRAASSAALDAWPLEPLG
NADTWRCLHGTALATLRRVLGFKSFYSPVTFETDTNTGLLLKTIPDEHALNNDNTPSTGVLRANFPVAIDVSAVSACNAHTQGTSLAYARLTALKSNGDT
QQQTPLDVEVITPKAYIRRKYKSTFSPPIEREGQTSDLFNLEERRLVLSGNRAIVVRVLLPCYFDCLTTDSTVTSSLSILATYRLWYAAAFGKPGVVRPI
FAYLGPELNPKGEDRDYFCTVGFPGWTTLRTQTPAVESIRTATEMYMETDGLWPVTGIQAFHYLAPWGQHPPLPPRVQDLIGQIPQDTGHADATVNWDAG
RISTVFKQPVQLQDRWMAKFDFSAFFPTIYCAMFPMHFRLGKIVLARMRRGMGCLKPALVSFFGGLRHILPSIYKAIIFIANEISLCVEQTALEQGFAIC
TYIKDGFWGIFTDLHTRNVCSDQARCSALNLAATCERAVTGLLRIQLGLNFTPAMEPVLRVEGVYTHAFTWCTTGSWLWNLQTNTPPDLVGVPWRSQAAR
DLKERLSGLLCTATKIRERIQENCIWDHVLYDIWAGQVVEAARKTYVDFFEHVFDRRYTPVYWSLQEQNSETKAIPASYLTYGHMQDKDYKPRQIIMVRN
PNPHGPPTVVYWELLPSCACIPPIDCAAHLKPLIHTFVTIINHLLDAHNDFSSPSLKFTDDPLASYNFLFL
NADTWRCLHGTALATLRRVLGFKSFYSPVTFETDTNTGLLLKTIPDEHALNNDNTPSTGVLRANFPVAIDVSAVSACNAHTQGTSLAYARLTALKSNGDT
QQQTPLDVEVITPKAYIRRKYKSTFSPPIEREGQTSDLFNLEERRLVLSGNRAIVVRVLLPCYFDCLTTDSTVTSSLSILATYRLWYAAAFGKPGVVRPI
FAYLGPELNPKGEDRDYFCTVGFPGWTTLRTQTPAVESIRTATEMYMETDGLWPVTGIQAFHYLAPWGQHPPLPPRVQDLIGQIPQDTGHADATVNWDAG
RISTVFKQPVQLQDRWMAKFDFSAFFPTIYCAMFPMHFRLGKIVLARMRRGMGCLKPALVSFFGGLRHILPSIYKAIIFIANEISLCVEQTALEQGFAIC
TYIKDGFWGIFTDLHTRNVCSDQARCSALNLAATCERAVTGLLRIQLGLNFTPAMEPVLRVEGVYTHAFTWCTTGSWLWNLQTNTPPDLVGVPWRSQAAR
DLKERLSGLLCTATKIRERIQENCIWDHVLYDIWAGQVVEAARKTYVDFFEHVFDRRYTPVYWSLQEQNSETKAIPASYLTYGHMQDKDYKPRQIIMVRN
PNPHGPPTVVYWELLPSCACIPPIDCAAHLKPLIHTFVTIINHLLDAHNDFSSPSLKFTDDPLASYNFLFL
771
Not Available
Not Available
01-07-1989
Inferred from homology
| Amino Acid | Count | % Frequency | Amino Acid | Count | % Frequency |
|---|---|---|---|---|---|
| Alanine (A) | Leucine (L) | ||||
| Arginine (R) | Lysine (K) | ||||
| Asparagine (N) | Methionine (M) | ||||
| Aspartic Acid (D) | Phenylalanine (F) | ||||
| Cysteine (C) | Proline (P) | ||||
| Glutamine (Q) | Serine (S) | ||||
| Glutamic Acid (E) | Threonine (T) | ||||
| Glycine (G) | Tryptophan (W) | ||||
| Histidine (H) | Tyrosine (Y) | ||||
| Isoleucine (I) | Valine (V) |
| % Number of Residues in Helices | % Number of Residues in Strands | % Number of Residues in Coils |
|---|---|---|
Component of the helicase/primase complex. Unwinds the DNA at the replication forks and generates single-stranded DNA for both leading and lagging strand synthesis. The primase synthesizes short RNA primers on the lagging strand that the polymerase presumably elongates using dNTPs. The primase-associated factor has no known catalytic activity in the complex and may serve to facilitate the formation of the replisome by directly interacting with the origin-binding protein and the polymerase.
Not Available
Host nucleus .
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Predicted/Modelled
Not Available
Not Available
Protein couldn't be modeled using I-Tasser and Raptor X because of length constraints of the software.
Not Available
- Million Molecules
Best 20 Hit molecules
Not Available