Results | viHumans

UniProt ID

P07577

Status

Reviewed

Host

Canis Lupus Familiaris (Dog) (Canis Familiaris) [TaxID: 9615]; Homo Sapiens (Human) [TaxID: 9606]

Gene Name

SH[Gene ID: 3160797 ]

Protein Name

Small hydrophobic protein

Organism Name

Parainfluenza Virus 5 (strain W3) (PIV5) (Simian Virus 5)

Taxonomic Lineage

Viruses> SsRNA Viruses> SsRNA Negative-strand Viruses> Mononegavirales> Paramyxoviridae> Rubulavirus> Mammalian Rubulavirus 5> Parainfluenza Virus 5 (strain W3) (PIV5) (Simian Virus 5)

RefSeq

Not Available

PubMed ID

4020965 ; 2836617 ; 11287556

Pathways Involved

Various pathway(s) in which protein is involved

KEGG

vg:3160797

Reactome

Not Available

Sequence

							MLPDPEDPESKKATRRAGNLIICFLFIFFLFVTFIVPTLRHLLS
						

Length

44

Alternate Sequence

Not Available

Non-standard residue

Not Available

Date of last Sequence modification

01-04-1988

Protein Existence

Inferred from homology

Amino Acid composition

Amino Acid	Count	% Frequency	Amino Acid	Count	% Frequency
Alanine (A)			Leucine (L)
Arginine (R)			Lysine (K)
Asparagine (N)			Methionine (M)
Aspartic Acid (D)			Phenylalanine (F)
Cysteine (C)			Proline (P)
Glutamine (Q)			Serine (S)
Glutamic Acid (E)			Threonine (T)
Glycine (G)			Tryptophan (W)
Histidine (H)			Tyrosine (Y)
Isoleucine (I)			Valine (V)

Sum of Absolute Deviation from Amino Acid Occurrence Frequencies

Aliphatic Index

Instability Index

Secondary Structure features

% Number of Residues in Helices	% Number of Residues in Strands	% Number of Residues in Coils

Structural Difficulty(SD) index

Role(s)

Inhibits TNF-alpha signaling and seems to block apoptosis in host infected cells.

EC

Not Available

Experimentally known GO terms

GO:0016021 ; GO:0020002 ; GO:0055036

Subcellular Location

♦ Virion membrane
♦ Single-pass type II membrane protein . Host cell membrane
♦ Single-pass type II membrane protein .

Domain(s)

Not Available

Motif(s)

Not Available

Methods of 3D structure generation

Predicted/Modelled

Experimetally known structure

Not Available

Active Site(s)

Not Available

Predicted 3D Structures

Protein couldn't be modeled using I-Tasser and Raptor X because of length constraints of the software.

Experimentally known Ligand(s)

Not Available

Virtually Screened Ligands

Virtual screening has been performed using RASPD

						Million Molecules

					
Best 20 Hit molecules 
Not Available