Results | viHumans

UniProt ID

F5HGK9

Status

Reviewed

Host

Homo Sapiens (Human) [TaxID: 9606]

Gene Name

ORF43[Gene ID: 4961497 ]

Protein Name

Portal protein

Organism Name

Human Herpesvirus 8 Type P (isolate GK18) (HHV-8) (Kaposi's Sarcoma-associated Herpesvirus)

Taxonomic Lineage

Viruses> DsDNA Viruses> No RNA Stage> Herpesvirales> Herpesviridae> Gammaherpesvirinae> Rhadinovirus> Human Herpesvirus 8 (HHV-8) (Kaposi's Sarcoma-associated Herpesvirus)> Human Herpesvirus 8 Type P (isolate GK18) (HHV-8) (Kaposi's Sarcoma-associated Herpesvirus)

RefSeq

NC_009333.1 ; AF148805.2

PubMed ID

10400794 ; 16760382

Pathways Involved

Various pathway(s) in which protein is involved

KEGG

vg:4961497

Reactome

Not Available

Sequence

							MLRMNPGLGSSISVHPSELSISLFEILQGKYSYVRGQTLHCSLRNPGVFFRQLFIHLYKNALANCSYDHVLSDWRTYESSAKTRWPEKEAQWGSYRRSTF
DSWAQTMRMTLDHLLLNAINRVLYAKTQLSYERYVDWVVTVGMVPVVKHTPDHKLVNSIQEQLMKDCQRLASGEKTIGRILTSVTQEISNLVSSLSALYI
PGYSEVSIDYDCVKNTFVGLYKQKRVHVEVITMPAILAGRVIFDSPIQRMYTSIMSCHRTAEHAKLCQLLNTAPTKALVGSACNNVYKDIMTHLEQASQR
TDPKRELLNLLMKLAENKTVSGVTDVVEDFVTDVSQNIVDKNKLFGTGQETTTQGLRRQVSNSVFKCLTNQINEQFDTITQLEKERELCMKRLKCIETQL
SHQQPGDAKGPGSVNLLTANTFQSLGRLQDPSLQLTSSHIPSGSAVLNSFFSSYIPPVRESMKDLTNLWESEMFQTYKLAPVVDNQGQRLSVTYSQDTIS
ILLGPFTYVIADLLQMELISHSFVSSSLQDIAAYLYQTSRLFVYITDVGQKYCLVTPPFENVPGKGPGETDWSANEYSCPEDSRVRRGLSRIPPPCGAPP
CPGSA
						

Length

605

Alternate Sequence

Not Available

Non-standard residue

Not Available

Date of last Sequence modification

28-06-2011

Protein Existence

Inferred from homology

Amino Acid composition

Amino Acid	Count	% Frequency	Amino Acid	Count	% Frequency
Alanine (A)			Leucine (L)
Arginine (R)			Lysine (K)
Asparagine (N)			Methionine (M)
Aspartic Acid (D)			Phenylalanine (F)
Cysteine (C)			Proline (P)
Glutamine (Q)			Serine (S)
Glutamic Acid (E)			Threonine (T)
Glycine (G)			Tryptophan (W)
Histidine (H)			Tyrosine (Y)
Isoleucine (I)			Valine (V)

Sum of Absolute Deviation from Amino Acid Occurrence Frequencies

Aliphatic Index

Instability Index

Secondary Structure features

% Number of Residues in Helices	% Number of Residues in Strands	% Number of Residues in Coils

Structural Difficulty(SD) index

Role(s)

Forms a portal in the viral capsid through which viral DNA is translocated during DNA packaging. Assembles as a dodecamer at a single fivefold axe of the T=16 icosahedric capsid. Binds to the molecular motor that translocates the viral DNA, termed terminase.

EC

Not Available

Experimentally known GO terms

GO:0006323 ; GO:0019012 ; GO:0042025

Subcellular Location

Virion . Host nucleus .

Domain(s)

Not Available

Motif(s)

Not Available

Methods of 3D structure generation

Predicted/Modelled

Experimetally known structure

Not Available

Active Site(s)

Not Available

Predicted 3D Structures

Protein couldn't be modeled using I-Tasser and Raptor X because of length constraints of the software.

Experimentally known Ligand(s)

Not Available

Virtually Screened Ligands

Virtual screening has been performed using RASPD

						Million Molecules

					
Best 20 Hit molecules 
Not Available