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SCFBio
PvP01_1268900
Protein Name: Translocation protein sec62
Sequence Information
Sequence Length:
376
Download Sequence
Sequence:
1
MSRSEDLDPDMLALLTCAFDEGVKVKGAVEVGKRAVEYFRGDEFVHFLYTRRDMLKKKFPTLLQNRTLADLKDIEEFSDT
80
81
FIQKGFIYKAQYKPIKGINEIDENGMYRRPKWPRRLIMSSKQNFDRTSFYILVHERNKKLQYLMLITLISIVLICCMFPI
160
161
WPLRLKLALWHLSVVFISLMSVIVLIRLFLFIFFWFFGVDYWLFPNLFDEECNVVESFTPVHQWIYRNDTWLLVIARMFT
240
241
AVLLAIGIHQLGKTHSISDIGNFATQSFIDIIEWGNKKLAASPENVSMYKSLDSKATFEVEFQDDGVVYDENEENYDCLK
320
321
GCGFQTFEELVRKCFLKCECMEKVIKSECYKKKCSRVTKEVLDEAHKEACFGKKDK
376
Amino Acid Composition
Frequency Percentage
11
10
9
8
7
6
5
4
3
2
1
4.25
16
ALA
4.78
18
ARG
3.45
13
ASN
6.11
23
ASP
3.19
12
CYS
7.44
28
GLU
2.65
10
GLN
3.19
12
GLY
1.86
7
HIS
7.18
27
ILE
10.37
39
LEU
9.04
34
LYS
2.92
11
MET
7.97
30
PHE
2.65
10
PRO
5.31
20
SER
3.98
15
THR
2.12
8
TRP
3.45
13
TYR
6.91
26
VAL
Amino Acid
External Database Links :
Molecular Weight:
44206
Sum of Absolute Deviation from
Amino Acid Occurrence Frequencies:
29.99
Aliphatic Index:
92.72
Instability Index:
42.69
Isoelectric Point:
7.61
Secondary Structure Information
Secondary Structure features
% Number of Residues in Helices
44.14
% Number of Residues in Strands
6.64
% Number of Residues in Coils
49.20
Structural Difficulty(SD) Index: 49.83
Secondary Structure Cartoon Form (PSIPRED)
Conf
9
8
8
7
8
8
9
9
8
9
9
9
9
9
9
9
9
9
9
8
5
9
9
8
6
4
6
7
6
5
6
8
7
6
4
6
6
6
6
4
8
9
9
9
9
9
9
9
7
6
8
8
8
8
8
8
7
5
7
6
Cart
C
C
C
C
C
C
C
C
H
H
H
H
H
H
H
H
H
H
H
H
H
C
C
C
C
E
E
E
E
E
C
C
C
C
E
E
E
E
E
E
H
H
H
H
H
H
H
H
H
C
C
H
H
H
H
H
H
H
C
C
Pred
C
1
C
2
C
3
C
4
C
5
C
6
C
7
C
8
H
9
H
10
H
11
H
12
H
13
H
14
H
15
H
16
H
17
H
18
H
19
H
20
H
21
C
22
C
23
C
24
C
25
E
26
E
27
E
28
E
29
E
30
C
31
C
32
C
33
C
34
E
35
E
36
E
37
E
38
E
39
E
40
H
41
H
42
H
43
H
44
H
45
H
46
H
47
H
48
H
49
C
50
C
51
H
52
H
53
H
54
H
55
H
56
H
57
H
58
C
59
C
60
AA
M
1
S
2
R
3
S
4
E
5
D
6
L
7
D
8
P
9
D
10
M
11
L
12
A
13
L
14
L
15
T
16
C
17
A
18
F
19
D
20
E
21
G
22
V
23
K
24
V
25
K
26
G
27
A
28
V
29
E
30
V
31
G
32
K
33
R
34
A
35
V
36
E
37
Y
38
F
39
R
40
G
41
D
42
E
43
F
44
V
45
H
46
F
47
L
48
Y
49
T
50
R
51
R
52
D
53
M
54
L
55
K
56
K
57
K
58
F
59
P
60
Conf
4
4
5
7
8
8
8
8
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
8
9
8
7
8
8
8
8
8
5
5
6
6
6
6
6
7
7
8
8
8
8
8
7
7
7
7
8
8
7
5
6
8
7
6
6
8
Cart
C
C
C
C
C
C
C
C
C
C
H
H
H
H
H
H
H
H
H
H
H
H
H
H
C
C
E
E
E
E
E
E
E
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
E
E
E
E
C
C
Pred
C
61
C
62
C
63
C
64
C
65
C
66
C
67
C
68
C
69
C
70
H
71
H
72
H
73
H
74
H
75
H
76
H
77
H
78
H
79
H
80
H
81
H
82
H
83
H
84
C
85
C
86
E
87
E
88
E
89
E
90
E
91
E
92
E
93
C
94
C
95
C
96
C
97
C
98
C
99
C
100
C
101
C
102
C
103
C
104
C
105
C
106
C
107
C
108
C
109
C
110
C
111
C
112
C
113
C
114
E
115
E
116
E
117
E
118
C
119
C
120
AA
T
61
L
62
L
63
Q
64
N
65
R
66
T
67
L
68
A
69
D
70
L
71
K
72
D
73
I
74
E
75
E
76
F
77
S
78
D
79
T
80
F
81
I
82
Q
83
K
84
G
85
F
86
I
87
Y
88
K
89
A
90
Q
91
Y
92
K
93
P
94
I
95
K
96
G
97
I
98
N
99
E
100
I
101
D
102
E
103
N
104
G
105
M
106
Y
107
R
108
R
109
P
110
K
111
W
112
P
113
R
114
R
115
L
116
I
117
M
118
S
119
S
120
Conf
7
6
7
8
8
8
8
5
7
9
9
9
9
7
7
8
8
5
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
8
6
5
6
5
7
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
Cart
C
C
C
C
C
C
C
E
E
E
E
E
E
E
C
C
C
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
Pred
C
121
C
122
C
123
C
124
C
125
C
126
C
127
E
128
E
129
E
130
E
131
E
132
E
133
E
134
C
135
C
136
C
137
H
138
H
139
H
140
H
141
H
142
H
143
H
144
H
145
H
146
H
147
H
148
H
149
H
150
H
151
H
152
H
153
H
154
H
155
H
156
H
157
H
158
H
159
H
160
H
161
H
162
H
163
H
164
H
165
H
166
H
167
H
168
H
169
H
170
H
171
H
172
H
173
H
174
H
175
H
176
H
177
H
178
H
179
H
180
AA
K
121
Q
122
N
123
F
124
D
125
R
126
T
127
S
128
F
129
Y
130
I
131
L
132
V
133
H
134
E
135
R
136
N
137
K
138
K
139
L
140
Q
141
Y
142
L
143
M
144
L
145
I
146
T
147
L
148
I
149
S
150
I
151
V
152
L
153
I
154
C
155
C
156
M
157
F
158
P
159
I
160
W
161
P
162
L
163
R
164
L
165
K
166
L
167
A
168
L
169
W
170
H
171
L
172
S
173
V
174
V
175
F
176
I
177
S
178
L
179
M
180
Conf
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
8
5
7
8
6
7
8
7
6
8
8
8
7
6
6
7
8
7
4
7
7
6
5
4
6
5
4
5
4
5
6
7
8
8
7
6
4
4
5
6
5
5
6
7
7
Cart
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
C
C
C
E
E
E
C
C
C
C
C
C
C
C
C
C
E
E
E
E
E
C
C
C
E
E
E
C
C
C
C
C
C
C
C
E
E
E
E
H
H
H
H
Pred
H
181
H
182
H
183
H
184
H
185
H
186
H
187
H
188
H
189
H
190
H
191
H
192
H
193
H
194
H
195
H
196
H
197
C
198
C
199
C
200
E
201
E
202
E
203
C
204
C
205
C
206
C
207
C
208
C
209
C
210
C
211
C
212
C
213
E
214
E
215
E
216
E
217
E
218
C
219
C
220
C
221
E
222
E
223
E
224
C
225
C
226
C
227
C
228
C
229
C
230
C
231
C
232
E
233
E
234
E
235
E
236
H
237
H
238
H
239
H
240
AA
S
181
V
182
I
183
V
184
L
185
I
186
R
187
L
188
F
189
L
190
F
191
I
192
F
193
F
194
W
195
F
196
F
197
G
198
V
199
D
200
Y
201
W
202
L
203
F
204
P
205
N
206
L
207
F
208
D
209
E
210
E
211
C
212
N
213
V
214
V
215
E
216
S
217
F
218
T
219
P
220
V
221
H
222
Q
223
W
224
I
225
Y
226
R
227
N
228
D
229
T
230
W
231
L
232
L
233
V
234
I
235
A
236
R
237
M
238
F
239
T
240
Conf
7
8
8
8
8
8
8
8
7
7
6
5
5
7
8
8
8
8
8
8
8
7
7
6
6
5
7
8
8
8
8
8
7
5
7
6
5
4
5
7
7
8
7
7
6
7
7
7
7
7
7
6
7
7
7
7
7
7
7
7
Cart
H
H
H
H
H
H
H
H
H
H
H
H
C
C
C
C
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
Pred
H
241
H
242
H
243
H
244
H
245
H
246
H
247
H
248
H
249
H
250
H
251
H
252
C
253
C
254
C
255
C
256
H
257
H
258
H
259
H
260
H
261
H
262
H
263
H
264
H
265
H
266
H
267
H
268
H
269
H
270
H
271
H
272
H
273
H
274
C
275
C
276
C
277
C
278
C
279
C
280
C
281
C
282
C
283
C
284
C
285
C
286
C
287
C
288
C
289
C
290
C
291
C
292
C
293
C
294
C
295
C
296
C
297
C
298
C
299
C
300
AA
A
241
V
242
L
243
L
244
A
245
I
246
G
247
I
248
H
249
Q
250
L
251
G
252
K
253
T
254
H
255
S
256
I
257
S
258
D
259
I
260
G
261
N
262
F
263
A
264
T
265
Q
266
S
267
F
268
I
269
D
270
I
271
I
272
E
273
W
274
G
275
N
276
K
277
K
278
L
279
A
280
A
281
S
282
P
283
E
284
N
285
V
286
S
287
M
288
Y
289
K
290
S
291
L
292
D
293
S
294
K
295
A
296
T
297
F
298
E
299
V
300
Conf
7
6
7
7
7
8
8
7
7
7
8
8
7
6
5
7
8
7
7
7
6
5
7
7
8
7
9
9
9
9
9
9
9
9
8
5
5
6
7
8
9
9
9
9
9
8
5
4
4
4
4
5
7
8
6
9
9
9
9
9
Cart
C
C
C
C
C
C
C
C
C
C
C
C
C
C
H
H
H
H
H
H
H
H
C
C
C
C
H
H
H
H
H
H
H
H
H
H
C
C
H
H
H
H
H
H
H
H
H
H
C
C
C
C
C
C
C
H
H
H
H
H
Pred
C
301
C
302
C
303
C
304
C
305
C
306
C
307
C
308
C
309
C
310
C
311
C
312
C
313
C
314
H
315
H
316
H
317
H
318
H
319
H
320
H
321
H
322
C
323
C
324
C
325
C
326
H
327
H
328
H
329
H
330
H
331
H
332
H
333
H
334
H
335
H
336
C
337
C
338
H
339
H
340
H
341
H
342
H
343
H
344
H
345
H
346
H
347
H
348
C
349
C
350
C
351
C
352
C
353
C
354
C
355
H
356
H
357
H
358
H
359
H
360
AA
E
301
F
302
Q
303
D
304
D
305
G
306
V
307
V
308
Y
309
D
310
E
311
N
312
E
313
E
314
N
315
Y
316
D
317
C
318
L
319
K
320
G
321
C
322
G
323
F
324
Q
325
T
326
F
327
E
328
E
329
L
330
V
331
R
332
K
333
C
334
F
335
L
336
K
337
C
338
E
339
C
340
M
341
E
342
K
343
V
344
I
345
K
346
S
347
E
348
C
349
Y
350
K
351
K
352
K
353
C
354
S
355
R
356
V
357
T
358
K
359
E
360
Conf
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
8
8
7
7
6
6
5
5
6
6
9
9
Cart
H
H
H
H
H
H
H
H
H
H
H
H
H
H
C
C
Pred
H
361
H
362
H
363
H
364
H
365
H
366
H
367
H
368
H
369
H
370
H
371
H
372
H
373
H
374
C
375
C
376
AA
V
361
L
362
D
363
E
364
A
365
H
366
K
367
E
368
A
369
C
370
F
371
G
372
K
373
K
374
D
375
K
376
Legend:
Helix
Strand
Coil
Conf:
-
+
Confidence of prediction
Cart:
3-state assignment cartoon
Pred:
3-state prediction
AA:
Target Sequence
Tertiary Structural Information
Models
BhageerathH
+
RaptorX
I-TASSER
View Structure in full screen
ProtSAV
PROCHECK
Verify3D
ERRAT
Naccess
Ligand Binding Site Information
Models
BhageerathH
+
RaptorX
I-TASSER
Ligand Binding Site
Pocket 1
Pocket 2
Pocket 3
Pocket 4
ActiveSite
FPocket
LigSite
Functional Annotations
InterPro
LocTree
ProBiS
SHIFTER
UniProt
GO:0015031
GO:0005634
GO:0009408
GO:0015031
GO:0015031
GO:0030176
GO:0005737
GO:0016020
GO:0030176
GO:0030176
--
GO:0016607
GO:0016021
GO:0031207
--
--
GO:0030176
GO:0055085
--
--
--
GO:0031207
GO:0070588
--
--
--
GO:0071013
--
--
--
Pathway Annotation
Protein Export
Protein Processing in Endoplasmic Reticulum
