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SCFBio
PvP01_0924600
Protein Name: Endoplasmic reticulum oxidoreductin (EC 1.8.4.-)
Sequence Information
Sequence Length:
467
Download Sequence
Sequence:
1
MKLAVVSVLLPVLFLGLFLKSKDQEVLLSYGHFLKNTFKELLLFFNIFDIEFPPSYVQNEKLLGLHVRDIEKDAYTAYPI
80
81
LKELKQKDYFRIFKVNLHIPCKLSKVNEKCKEIKKCSVCECHDDEIPYNFRTNEIEIIEDKMSSEDLKKTFIESKLYKDI
160
161
LGIYAPSDEGFLSYVDLVYNSPSFTAYEGRNIWNKIYRENCFQKEENKCHEMKSFYKIISGMQSNIAILSAEYHYLKNDF
240
241
VFGDMHTDDVMKSDYFKKQNYEYSMQFFKEKIALYPERIENLYFTFAILLRAMCRLKSLVSQCKCNSGHAQNDKEALKVL
320
321
NDLLGSFYHSCASEQFLEPIFPTQGKEILAKFMNITNILDCVPCVKCRLHGKLKTTALQIALVEGMSYEHIGSLERNEIT
400
401
ALINSLYYFADSIIILNKFEERQKLKRATFIFYLLSFCFFLILIIYSIVFITVRNCKKMKKKKKKIS
467
Amino Acid Composition
Frequency Percentage
12
11
10
9
8
7
6
5
4
3
2
1
4.06
19
ALA
2.78
13
ARG
5.35
25
ASN
4.49
21
ASP
3.42
16
CYS
7.70
36
GLU
2.78
13
GLN
3.42
16
GLY
2.35
11
HIS
8.77
41
ILE
11.34
53
LEU
11.34
53
LYS
2.35
11
MET
7.49
35
PHE
2.56
12
PRO
6.85
32
SER
2.99
14
THR
.21
1
TRP
5.56
26
TYR
4.49
21
VAL
Amino Acid
External Database Links :
Molecular Weight:
54841
Sum of Absolute Deviation from
Amino Acid Occurrence Frequencies:
41.17
Aliphatic Index:
95.50
Instability Index:
47.21
Isoelectric Point:
8.48
Secondary Structure Information
Secondary Structure features
% Number of Residues in Helices
47.96
% Number of Residues in Strands
4.71
% Number of Residues in Coils
47.32
Structural Difficulty(SD) Index: 33.37
Secondary Structure Cartoon Form (PSIPRED)
Conf
9
4
6
7
5
4
7
8
9
9
9
9
9
9
9
9
9
9
9
9
8
5
5
5
5
4
3
3
3
5
5
5
5
6
5
5
7
7
7
7
5
8
9
8
7
6
5
4
3
4
6
7
7
6
5
4
4
5
7
7
Cart
C
C
E
E
E
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
C
C
C
C
C
C
C
C
C
C
H
H
H
C
C
C
C
C
E
E
E
E
E
E
E
E
E
C
C
C
C
C
C
E
E
C
C
C
Pred
C
1
C
2
E
3
E
4
E
5
H
6
H
7
H
8
H
9
H
10
H
11
H
12
H
13
H
14
H
15
H
16
H
17
H
18
H
19
H
20
H
21
H
22
C
23
C
24
C
25
C
26
C
27
C
28
C
29
C
30
C
31
C
32
H
33
H
34
H
35
C
36
C
37
C
38
C
39
C
40
E
41
E
42
E
43
E
44
E
45
E
46
E
47
E
48
E
49
C
50
C
51
C
52
C
53
C
54
C
55
E
56
E
57
C
58
C
59
C
60
AA
M
1
K
2
L
3
A
4
V
5
V
6
S
7
V
8
L
9
L
10
P
11
V
12
L
13
F
14
L
15
G
16
L
17
F
18
L
19
K
20
S
21
K
22
D
23
Q
24
E
25
V
26
L
27
L
28
S
29
Y
30
G
31
H
32
F
33
L
34
K
35
N
36
T
37
F
38
K
39
E
40
L
41
L
42
L
43
F
44
F
45
N
46
I
47
F
48
D
49
I
50
E
51
F
52
P
53
P
54
S
55
Y
56
V
57
Q
58
N
59
E
60
Conf
7
6
5
7
7
7
9
9
9
8
9
9
9
9
9
9
9
9
9
9
9
9
9
9
8
7
8
9
7
5
8
9
9
9
8
4
8
9
9
9
9
9
9
7
6
5
6
7
6
6
6
6
7
8
8
7
5
5
6
6
Cart
C
C
C
C
C
C
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
C
C
C
E
E
E
E
E
E
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
E
E
E
Pred
C
61
C
62
C
63
C
64
C
65
C
66
H
67
H
68
H
69
H
70
H
71
H
72
H
73
H
74
H
75
H
76
H
77
H
78
H
79
H
80
H
81
H
82
H
83
H
84
H
85
H
86
C
87
C
88
C
89
E
90
E
91
E
92
E
93
E
94
E
95
C
96
C
97
C
98
C
99
C
100
C
101
C
102
C
103
C
104
C
105
C
106
C
107
C
108
C
109
C
110
C
111
C
112
C
113
C
114
C
115
C
116
C
117
E
118
E
119
E
120
AA
K
61
L
62
L
63
G
64
L
65
H
66
V
67
R
68
D
69
I
70
E
71
K
72
D
73
A
74
Y
75
T
76
A
77
Y
78
P
79
I
80
L
81
K
82
E
83
L
84
K
85
Q
86
K
87
D
88
Y
89
F
90
R
91
I
92
F
93
K
94
V
95
N
96
L
97
H
98
I
99
P
100
C
101
K
102
L
103
S
104
K
105
V
106
N
107
E
108
K
109
C
110
K
111
E
112
I
113
K
114
K
115
C
116
S
117
V
118
C
119
E
120
Conf
7
8
7
7
7
9
9
7
6
5
7
5
6
6
5
7
7
7
7
8
8
7
7
7
7
6
5
6
7
7
6
6
5
6
5
5
5
5
6
5
5
6
6
7
7
7
8
8
9
9
8
8
5
7
8
7
5
6
6
8
Cart
C
C
H
H
H
C
C
C
C
C
C
C
H
H
H
C
C
C
C
C
C
C
C
C
C
C
C
H
H
H
H
H
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
E
E
E
E
C
C
C
C
Pred
C
121
C
122
H
123
H
124
H
125
C
126
C
127
C
128
C
129
C
130
C
131
C
132
H
133
H
134
H
135
C
136
C
137
C
138
C
139
C
140
C
141
C
142
C
143
C
144
C
145
C
146
C
147
H
148
H
149
H
150
H
151
H
152
C
153
C
154
C
155
C
156
C
157
C
158
C
159
C
160
C
161
C
162
C
163
C
164
C
165
C
166
C
167
C
168
C
169
C
170
C
171
C
172
E
173
E
174
E
175
E
176
C
177
C
178
C
179
C
180
AA
C
121
H
122
D
123
D
124
E
125
I
126
P
127
Y
128
N
129
F
130
R
131
T
132
N
133
E
134
I
135
E
136
I
137
I
138
E
139
D
140
K
141
M
142
S
143
S
144
E
145
D
146
L
147
K
148
K
149
T
150
F
151
I
152
E
153
S
154
K
155
L
156
Y
157
K
158
D
159
I
160
L
161
G
162
I
163
Y
164
A
165
P
166
S
167
D
168
E
169
G
170
F
171
L
172
S
173
Y
174
V
175
D
176
L
177
V
178
Y
179
N
180
Conf
9
8
8
8
9
9
9
9
8
5
8
9
9
9
9
9
9
9
8
5
8
8
9
9
8
8
7
7
9
8
9
9
9
9
9
9
9
9
9
8
7
7
7
8
8
9
9
9
9
9
9
9
9
7
7
8
7
7
6
6
Cart
C
C
C
C
C
C
C
C
C
C
H
H
H
H
H
H
H
H
H
C
C
C
C
C
C
C
C
C
C
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
C
C
C
C
C
C
Pred
C
181
C
182
C
183
C
184
C
185
C
186
C
187
C
188
C
189
C
190
H
191
H
192
H
193
H
194
H
195
H
196
H
197
H
198
H
199
C
200
C
201
C
202
C
203
C
204
C
205
C
206
C
207
C
208
C
209
H
210
H
211
H
212
H
213
H
214
H
215
H
216
H
217
H
218
H
219
H
220
H
221
H
222
H
223
H
224
H
225
H
226
H
227
H
228
H
229
H
230
H
231
H
232
H
233
H
234
C
235
C
236
C
237
C
238
C
239
C
240
AA
S
181
P
182
S
183
F
184
T
185
A
186
Y
187
E
188
G
189
R
190
N
191
I
192
W
193
N
194
K
195
I
196
Y
197
R
198
E
199
N
200
C
201
F
202
Q
203
K
204
E
205
E
206
N
207
K
208
C
209
H
210
E
211
M
212
K
213
S
214
F
215
Y
216
K
217
I
218
I
219
S
220
G
221
M
222
Q
223
S
224
N
225
I
226
A
227
I
228
L
229
S
230
A
231
E
232
Y
233
H
234
Y
235
L
236
K
237
N
238
D
239
F
240
Conf
6
6
7
7
6
6
6
6
6
6
6
7
7
7
7
8
8
8
8
7
6
5
6
7
7
8
9
9
9
9
8
7
7
8
9
7
8
9
9
9
8
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
8
8
Cart
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
H
H
H
H
H
H
H
H
C
C
C
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
Pred
C
241
C
242
C
243
C
244
C
245
C
246
C
247
C
248
C
249
C
250
C
251
C
252
C
253
C
254
C
255
C
256
C
257
C
258
C
259
C
260
C
261
C
262
C
263
C
264
H
265
H
266
H
267
H
268
H
269
H
270
H
271
H
272
C
273
C
274
C
275
H
276
H
277
H
278
H
279
H
280
H
281
H
282
H
283
H
284
H
285
H
286
H
287
H
288
H
289
H
290
H
291
H
292
H
293
H
294
H
295
H
296
H
297
H
298
H
299
H
300
AA
V
241
F
242
G
243
D
244
M
245
H
246
T
247
D
248
D
249
V
250
M
251
K
252
S
253
D
254
Y
255
F
256
K
257
K
258
Q
259
N
260
Y
261
E
262
Y
263
S
264
M
265
Q
266
F
267
F
268
K
269
E
270
K
271
I
272
A
273
L
274
Y
275
P
276
E
277
R
278
I
279
E
280
N
281
L
282
Y
283
F
284
T
285
F
286
A
287
I
288
L
289
L
290
R
291
A
292
M
293
C
294
R
295
L
296
K
297
S
298
L
299
V
300
Conf
8
6
7
8
8
8
8
9
9
8
9
9
9
9
9
9
9
9
9
9
9
9
9
8
7
6
5
5
5
5
6
5
7
7
6
5
7
7
6
5
6
8
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
8
6
Cart
H
H
C
C
C
C
C
C
C
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
C
C
C
C
C
C
H
H
H
H
H
C
C
C
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
Pred
H
301
H
302
C
303
C
304
C
305
C
306
C
307
C
308
C
309
H
310
H
311
H
312
H
313
H
314
H
315
H
316
H
317
H
318
H
319
H
320
H
321
H
322
H
323
H
324
H
325
C
326
C
327
C
328
C
329
C
330
C
331
H
332
H
333
H
334
H
335
H
336
C
337
C
338
C
339
H
340
H
341
H
342
H
343
H
344
H
345
H
346
H
347
H
348
H
349
H
350
H
351
H
352
H
353
H
354
H
355
H
356
H
357
H
358
H
359
H
360
AA
S
301
Q
302
C
303
K
304
C
305
N
306
S
307
G
308
H
309
A
310
Q
311
N
312
D
313
K
314
E
315
A
316
L
317
K
318
V
319
L
320
N
321
D
322
L
323
L
324
G
325
S
326
F
327
Y
328
H
329
S
330
C
331
A
332
S
333
E
334
Q
335
F
336
L
337
E
338
P
339
I
340
F
341
P
342
T
343
Q
344
G
345
K
346
E
347
I
348
L
349
A
350
K
351
F
352
M
353
N
354
I
355
T
356
N
357
I
358
L
359
D
360
Conf
5
7
8
8
6
5
4
4
3
5
6
8
9
9
9
9
9
9
9
9
9
9
9
9
8
6
8
7
8
8
6
6
6
6
4
4
7
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
Cart
C
C
C
C
C
C
E
E
E
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
C
C
C
C
C
C
C
C
C
C
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
Pred
C
361
C
362
C
363
C
364
C
365
C
366
E
367
E
368
E
369
H
370
H
371
H
372
H
373
H
374
H
375
H
376
H
377
H
378
H
379
H
380
H
381
H
382
H
383
H
384
H
385
C
386
C
387
C
388
C
389
C
390
C
391
C
392
C
393
C
394
C
395
H
396
H
397
H
398
H
399
H
400
H
401
H
402
H
403
H
404
H
405
H
406
H
407
H
408
H
409
H
410
H
411
H
412
H
413
H
414
H
415
H
416
H
417
H
418
H
419
H
420
AA
C
361
V
362
P
363
C
364
V
365
K
366
C
367
R
368
L
369
H
370
G
371
K
372
L
373
K
374
T
375
T
376
A
377
L
378
Q
379
I
380
A
381
L
382
V
383
E
384
G
385
M
386
S
387
Y
388
E
389
H
390
I
391
G
392
S
393
L
394
E
395
R
396
N
397
E
398
I
399
T
400
A
401
L
402
I
403
N
404
S
405
L
406
Y
407
Y
408
F
409
A
410
D
411
S
412
I
413
I
414
I
415
L
416
N
417
K
418
F
419
E
420
Conf
9
9
9
9
9
9
9
9
8
8
7
7
6
6
6
6
7
7
8
8
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
8
8
8
8
7
7
7
7
5
5
5
5
6
6
5
5
4
4
5
5
7
7
7
7
7
7
7
7
6
6
6
6
5
5
6
6
9
9
Cart
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
C
C
C
H
H
H
H
H
H
H
H
H
C
C
Pred
H
421
H
422
H
423
H
424
H
425
H
426
H
427
H
428
H
429
H
430
H
431
H
432
H
433
H
434
H
435
H
436
H
437
H
438
H
439
H
440
H
441
H
442
H
443
H
444
H
445
H
446
H
447
H
448
H
449
H
450
H
451
H
452
H
453
C
454
C
455
C
456
H
457
H
458
H
459
H
460
H
461
H
462
H
463
H
464
H
465
C
466
C
467
AA
E
421
R
422
Q
423
K
424
L
425
K
426
R
427
A
428
T
429
F
430
I
431
F
432
Y
433
L
434
L
435
S
436
F
437
C
438
F
439
F
440
L
441
I
442
L
443
I
444
I
445
Y
446
S
447
I
448
V
449
F
450
I
451
T
452
V
453
R
454
N
455
C
456
K
457
K
458
M
459
K
460
K
461
K
462
K
463
K
464
K
465
I
466
S
467
Legend:
Helix
Strand
Coil
Conf:
-
+
Confidence of prediction
Cart:
3-state assignment cartoon
Pred:
3-state prediction
AA:
Target Sequence
Tertiary Structural Information
Models
BhageerathH
+
RaptorX
I-TASSER
View Structure in full screen
ProtSAV
PROCHECK
Verify3D
ERRAT
Naccess
Ligand Binding Site Information
Models
BhageerathH
+
RaptorX
I-TASSER
Ligand Binding Site
Pocket 1
Pocket 2
Pocket 3
Pocket 4
ActiveSite
FPocket
LigSite
Functional Annotations
InterPro
LocTree
ProBiS
SHIFTER
UniProt
GO:0003756
GO:0005576
GO:0003756
GO:0003756
GO:0003756
GO:0005783
--
GO:0005783
--
GO:0005783
GO:0016671
--
GO:0016671
--
GO:0016021
GO:0055114
--
GO:0055114
--
GO:0016671
Pathway Annotation
Protein Processing in Endoplasmic Reticulum
