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SCFBio
PvP01_0808400
Protein Name: Tubulin beta chain
Sequence Information
Sequence Length:
445
Download Sequence
Sequence:
1
MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGTYRGDSDLQLERVDVFYNEATGGRYVPRAILMDLEPGTMDSVRAGP
80
81
FGQLFRPDNFVFGQTGAGNNWAKGHYTEGAELIDAVLDVVRKEAEGCDCLQGFQITHSLGGGTGSGMGTLLISKIREEYP
160
161
DRIMETFSVFPSPKVSDTVVEPYNATLSVHQLVENADEVQVIDNEALYDICFRTLKLTTPTYGDLNHLVSAAMSGVTCSL
240
241
RFPGQLNSDLRKLAVNLIPFPRLHFFMIGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMCASDPRHGRYLTACAMFRGR
320
321
MSTKEVDEQMLSVQNKNSSYFVEWIPHNTKSSVCDIPPKGLKMAVTFVGNSTAIQEMFKRVSDQFTAMFRRKAFLHWYTG
400
401
EGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEGEFEEEEGDVEA
445
Amino Acid Composition
Frequency Percentage
9
8
7
6
5
4
3
2
1
6.74
30
ALA
5.16
23
ARG
4.04
18
ASN
6.06
27
ASP
1.79
8
CYS
8.31
37
GLU
4.94
22
GLN
1.79
8
GLY
2.24
10
HIS
4.04
18
ILE
7.19
32
LEU
3.37
15
LYS
4.26
19
MET
5.61
25
PHE
4.26
19
PRO
6.29
28
SER
6.29
28
THR
.89
4
TRP
3.14
14
TYR
6.96
31
VAL
Amino Acid
External Database Links :
Molecular Weight:
49776
Sum of Absolute Deviation from
Amino Acid Occurrence Frequencies:
23.18
Aliphatic Index:
70.71
Instability Index:
31.62
Isoelectric Point:
4.5
Secondary Structure Information
Secondary Structure features
% Number of Residues in Helices
30.56
% Number of Residues in Strands
8.31
% Number of Residues in Coils
61.12
Structural Difficulty(SD) Index: 12.60
Secondary Structure Cartoon Form (PSIPRED)
Conf
9
6
7
9
9
9
9
9
5
8
6
6
4
6
6
7
7
9
9
9
9
9
9
9
9
9
9
9
8
9
9
9
9
9
8
8
8
7
6
5
5
6
7
6
5
5
5
4
4
4
4
4
5
6
7
8
8
8
7
5
Cart
C
C
E
E
E
E
E
E
E
C
C
C
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
Pred
C
1
C
2
E
3
E
4
E
5
E
6
E
7
E
8
E
9
C
10
C
11
C
12
H
13
H
14
H
15
H
16
H
17
H
18
H
19
H
20
H
21
H
22
H
23
H
24
H
25
H
26
H
27
H
28
C
29
C
30
C
31
C
32
C
33
C
34
C
35
C
36
C
37
C
38
C
39
C
40
C
41
C
42
C
43
C
44
C
45
C
46
C
47
C
48
C
49
C
50
C
51
C
52
C
53
C
54
C
55
C
56
C
57
C
58
C
59
C
60
AA
M
1
R
2
E
3
I
4
V
5
H
6
I
7
Q
8
A
9
G
10
Q
11
C
12
G
13
N
14
Q
15
I
16
G
17
A
18
K
19
F
20
W
21
E
22
V
23
I
24
S
25
D
26
E
27
H
28
G
29
I
30
D
31
P
32
S
33
G
34
T
35
Y
36
R
37
G
38
D
39
S
40
D
41
L
42
Q
43
L
44
E
45
R
46
V
47
D
48
V
49
F
50
Y
51
N
52
E
53
A
54
T
55
G
56
G
57
R
58
Y
59
V
60
Conf
5
6
7
6
5
4
7
8
9
9
8
5
4
5
5
4
4
7
9
8
7
7
7
7
7
8
7
6
6
5
5
6
7
7
7
7
8
7
7
7
6
6
5
5
5
4
4
5
5
5
7
8
8
9
9
9
9
9
9
9
Cart
E
E
E
E
E
C
C
C
C
C
C
C
E
E
E
E
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
H
H
H
H
H
H
H
H
H
H
H
Pred
E
61
E
62
E
63
E
64
E
65
C
66
C
67
C
68
C
69
C
70
C
71
C
72
E
73
E
74
E
75
E
76
C
77
C
78
C
79
C
80
C
81
C
82
C
83
C
84
C
85
C
86
C
87
C
88
C
89
C
90
C
91
C
92
C
93
C
94
C
95
C
96
C
97
C
98
C
99
C
100
C
101
C
102
C
103
C
104
C
105
C
106
C
107
C
108
C
109
H
110
H
111
H
112
H
113
H
114
H
115
H
116
H
117
H
118
H
119
H
120
AA
P
61
R
62
A
63
I
64
L
65
M
66
D
67
L
68
E
69
P
70
G
71
T
72
M
73
D
74
S
75
V
76
R
77
A
78
G
79
P
80
F
81
G
82
Q
83
L
84
F
85
R
86
P
87
D
88
N
89
F
90
V
91
F
92
G
93
Q
94
T
95
G
96
A
97
G
98
N
99
N
100
W
101
A
102
K
103
G
104
H
105
Y
106
T
107
E
108
G
109
A
110
E
111
L
112
I
113
D
114
A
115
V
116
L
117
D
118
V
119
V
120
Conf
9
9
9
9
8
6
8
9
9
7
7
6
5
5
6
7
6
5
6
7
8
9
9
9
8
8
7
8
8
9
9
9
9
9
9
9
8
6
7
8
8
6
6
7
8
8
7
5
5
6
7
8
7
7
7
7
8
7
6
6
Cart
H
H
H
H
H
H
C
C
C
C
C
C
C
E
E
E
E
E
C
C
C
C
C
C
C
C
H
H
H
H
H
H
H
H
H
H
H
H
C
C
C
C
E
E
E
E
E
E
E
C
C
C
C
C
C
C
C
C
C
C
Pred
H
121
H
122
H
123
H
124
H
125
H
126
C
127
C
128
C
129
C
130
C
131
C
132
C
133
E
134
E
135
E
136
E
137
E
138
C
139
C
140
C
141
C
142
C
143
C
144
C
145
C
146
H
147
H
148
H
149
H
150
H
151
H
152
H
153
H
154
H
155
H
156
H
157
H
158
C
159
C
160
C
161
C
162
E
163
E
164
E
165
E
166
E
167
E
168
E
169
C
170
C
171
C
172
C
173
C
174
C
175
C
176
C
177
C
178
C
179
C
180
AA
R
121
K
122
E
123
A
124
E
125
G
126
C
127
D
128
C
129
L
130
Q
131
G
132
F
133
Q
134
I
135
T
136
H
137
S
138
L
139
G
140
G
141
G
142
T
143
G
144
S
145
G
146
M
147
G
148
T
149
L
150
L
151
I
152
S
153
K
154
I
155
R
156
E
157
E
158
Y
159
P
160
D
161
R
162
I
163
M
164
E
165
T
166
F
167
S
168
V
169
F
170
P
171
S
172
P
173
K
174
V
175
S
176
D
177
T
178
V
179
V
180
Conf
6
7
6
6
5
4
7
8
9
9
9
9
8
8
6
5
5
4
4
4
5
5
6
6
7
8
9
9
9
9
9
9
9
8
5
8
8
8
9
9
9
7
5
5
6
7
7
8
8
8
7
7
6
5
5
4
6
6
7
8
Cart
C
C
C
C
C
H
H
H
H
H
H
H
H
H
H
H
H
H
H
C
C
C
C
C
H
H
H
H
H
H
H
H
H
H
H
C
C
C
C
C
C
C
C
H
H
H
H
H
H
H
H
H
H
H
H
C
C
C
C
C
Pred
C
181
C
182
C
183
C
184
C
185
H
186
H
187
H
188
H
189
H
190
H
191
H
192
H
193
H
194
H
195
H
196
H
197
H
198
H
199
C
200
C
201
C
202
C
203
C
204
H
205
H
206
H
207
H
208
H
209
H
210
H
211
H
212
H
213
H
214
H
215
C
216
C
217
C
218
C
219
C
220
C
221
C
222
C
223
H
224
H
225
H
226
H
227
H
228
H
229
H
230
H
231
H
232
H
233
H
234
H
235
C
236
C
237
C
238
C
239
C
240
AA
E
181
P
182
Y
183
N
184
A
185
T
186
L
187
S
188
V
189
H
190
Q
191
L
192
V
193
E
194
N
195
A
196
D
197
E
198
V
199
Q
200
V
201
I
202
D
203
N
204
E
205
A
206
L
207
Y
208
D
209
I
210
C
211
F
212
R
213
T
214
L
215
K
216
L
217
T
218
T
219
P
220
T
221
Y
222
G
223
D
224
L
225
N
226
H
227
L
228
V
229
S
230
A
231
A
232
M
233
S
234
G
235
V
236
T
237
C
238
S
239
L
240
Conf
8
9
9
8
7
6
7
7
4
8
9
9
9
8
7
5
7
8
8
8
7
6
4
5
5
5
6
6
7
7
8
7
5
5
5
5
4
5
5
5
5
5
4
6
6
7
8
9
9
9
9
9
8
7
6
5
5
6
5
4
Cart
C
C
C
C
C
C
C
C
C
H
H
H
H
H
H
H
C
C
C
C
C
C
C
E
E
C
C
C
C
C
C
C
C
C
C
C
H
H
H
H
H
H
H
C
C
H
H
H
H
H
H
H
H
H
H
C
C
C
C
C
Pred
C
241
C
242
C
243
C
244
C
245
C
246
C
247
C
248
C
249
H
250
H
251
H
252
H
253
H
254
H
255
H
256
C
257
C
258
C
259
C
260
C
261
C
262
C
263
E
264
E
265
C
266
C
267
C
268
C
269
C
270
C
271
C
272
C
273
C
274
C
275
C
276
H
277
H
278
H
279
H
280
H
281
H
282
H
283
C
284
C
285
H
286
H
287
H
288
H
289
H
290
H
291
H
292
H
293
H
294
H
295
C
296
C
297
C
298
C
299
C
300
AA
R
241
F
242
P
243
G
244
Q
245
L
246
N
247
S
248
D
249
L
250
R
251
K
252
L
253
A
254
V
255
N
256
L
257
I
258
P
259
F
260
P
261
R
262
L
263
H
264
F
265
F
266
M
267
I
268
G
269
F
270
A
271
P
272
L
273
T
274
S
275
R
276
G
277
S
278
Q
279
Q
280
Y
281
R
282
A
283
L
284
T
285
V
286
P
287
E
288
L
289
T
290
Q
291
Q
292
M
293
F
294
D
295
A
296
K
297
N
298
M
299
M
300
Conf
4
5
6
8
9
9
9
9
5
4
4
5
7
7
7
8
8
7
8
8
9
8
5
7
8
8
9
9
9
9
9
9
8
8
7
5
4
5
4
6
6
7
8
8
8
8
8
7
5
8
8
6
5
8
8
9
9
9
8
8
Cart
C
C
C
C
C
C
C
C
C
E
E
H
H
H
H
H
H
H
C
C
C
C
C
H
H
H
H
H
H
H
H
H
H
H
H
H
C
C
C
C
C
C
C
C
C
C
C
C
E
E
E
E
C
C
C
C
C
C
C
C
Pred
C
301
C
302
C
303
C
304
C
305
C
306
C
307
C
308
C
309
E
310
E
311
H
312
H
313
H
314
H
315
H
316
H
317
H
318
C
319
C
320
C
321
C
322
C
323
H
324
H
325
H
326
H
327
H
328
H
329
H
330
H
331
H
332
H
333
H
334
H
335
H
336
C
337
C
338
C
339
C
340
C
341
C
342
C
343
C
344
C
345
C
346
C
347
C
348
E
349
E
350
E
351
E
352
C
353
C
354
C
355
C
356
C
357
C
358
C
359
C
360
AA
C
301
A
302
S
303
D
304
P
305
R
306
H
307
G
308
R
309
Y
310
L
311
T
312
A
313
C
314
A
315
M
316
F
317
R
318
G
319
R
320
M
321
S
322
T
323
K
324
E
325
V
326
D
327
E
328
Q
329
M
330
L
331
S
332
V
333
Q
334
N
335
K
336
N
337
S
338
S
339
Y
340
F
341
V
342
E
343
W
344
I
345
P
346
H
347
N
348
T
349
K
350
S
351
S
352
V
353
C
354
D
355
I
356
P
357
P
358
K
359
G
360
Conf
8
6
5
7
8
8
8
6
5
8
8
6
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
8
7
6
5
7
8
8
7
7
6
5
7
9
9
9
7
8
9
9
9
9
9
9
9
9
9
9
9
9
9
9
Cart
C
C
E
E
E
E
E
E
C
C
C
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
C
H
H
H
H
H
H
H
C
C
C
C
C
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
Pred
C
361
C
362
E
363
E
364
E
365
E
366
E
367
E
368
C
369
C
370
C
371
H
372
H
373
H
374
H
375
H
376
H
377
H
378
H
379
H
380
H
381
H
382
H
383
H
384
H
385
H
386
H
387
H
388
H
389
H
390
H
391
C
392
H
393
H
394
H
395
H
396
H
397
H
398
H
399
C
400
C
401
C
402
C
403
C
404
H
405
H
406
H
407
H
408
H
409
H
410
H
411
H
412
H
413
H
414
H
415
H
416
H
417
H
418
H
419
H
420
AA
L
361
K
362
M
363
A
364
V
365
T
366
F
367
V
368
G
369
N
370
S
371
T
372
A
373
I
374
Q
375
E
376
M
377
F
378
K
379
R
380
V
381
S
382
D
383
Q
384
F
385
T
386
A
387
M
388
F
389
R
390
R
391
K
392
A
393
F
394
L
395
H
396
W
397
Y
398
T
399
G
400
E
401
G
402
M
403
D
404
E
405
M
406
E
407
F
408
T
409
E
410
A
411
E
412
S
413
N
414
M
415
N
416
D
417
L
418
V
419
S
420
Conf
9
9
9
9
9
9
9
9
9
9
9
9
7
7
7
7
7
7
5
5
5
5
5
5
6
6
7
7
7
7
6
6
6
6
5
5
4
4
5
5
5
5
4
4
6
6
7
7
9
9
Cart
H
H
H
H
H
H
H
C
C
C
C
C
C
C
C
C
C
C
H
H
H
H
C
C
C
Pred
H
421
H
422
H
423
H
424
H
425
H
426
H
427
C
428
C
429
C
430
C
431
C
432
C
433
C
434
C
435
C
436
C
437
C
438
H
439
H
440
H
441
H
442
C
443
C
444
C
445
AA
E
421
Y
422
Q
423
Q
424
Y
425
Q
426
D
427
A
428
T
429
A
430
E
431
E
432
E
433
G
434
E
435
F
436
E
437
E
438
E
439
E
440
G
441
D
442
V
443
E
444
A
445
Legend:
Helix
Strand
Coil
Conf:
-
+
Confidence of prediction
Cart:
3-state assignment cartoon
Pred:
3-state prediction
AA:
Target Sequence
Tertiary Structural Information
Models
BhageerathH
+
RaptorX
I-TASSER
View Structure in full screen
ProtSAV
PROCHECK
Verify3D
ERRAT
Naccess
Ligand Binding Site Information
Models
BhageerathH
+
RaptorX
I-TASSER
Ligand Binding Site
Pocket 1
Pocket 2
Pocket 3
Pocket 4
ActiveSite
FPocket
LigSite
Functional Annotations
InterPro
LocTree
ProBiS
SHIFTER
UniProt
GO:0003924
GO:0003924
GO:0003924
GO:0003924
GO:0007017
GO:0005200
GO:0007017
GO:0005874
GO:0005874
GO:0003924
GO:0003924
GO:0005525
GO:0005525
GO:0005200
--
GO:0005525
--
--
--
--
Pathway Annotation
Phagosome
