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SCFBio
PvP01_0702100
Protein Name: Tubulin alpha chain
Sequence Information
Sequence Length:
453
Download Sequence
Sequence:
1
MREVISIHVGQAGIQVGNACWELFCLEHGIQPDGQMPSDKAARANDDAFNTFFSETGAGKHVPRCVFVDLEPTVVDEVRT
80
81
GTYRQLFHPEQLISGKEDAANNFARGHYTIGKEVIDVCLDRIRKLADNCTGLQGFLMFSAVGGGTGSGFGCLMLERLSVD
160
161
YGKKSKLNFCCWPSPQVSTAVVEPYNSVLSTHSLLEHTDVAIMLDNEAIYDICKKNLDIERPTYTNLNRLIAQVISSLTA
240
241
SLRFDGALNVDVTEFQTNLVPYPRIHFMLSSYAPVVSAEKAYHEQLSVSEITNSAFEPANMMAKCDPRHGKYMACCLMYR
320
321
GDVVPKDVNAAVATIKTKRTIQFVDWCPTGFKCGINYQPPTVVPGGDLAKVMRAVCMISNSTAIAEVFSRMDQKFDLMYA
400
401
KRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGIETNEGEGEDEGYEADY
453
Amino Acid Composition
Frequency Percentage
9
8
7
6
5
4
3
2
1
8.38
38
ALA
4.41
20
ARG
4.41
20
ASN
6.18
28
ASP
3.31
15
CYS
7.72
35
GLU
3.09
14
GLN
3.31
15
GLY
2.42
11
HIS
4.85
22
ILE
6.84
31
LEU
4.63
21
LYS
3.31
15
MET
4.63
21
PHE
4.19
19
PRO
5.73
26
SER
5.29
24
THR
.88
4
TRP
3.75
17
TYR
8.38
38
VAL
Amino Acid
External Database Links :
Molecular Weight:
50224
Sum of Absolute Deviation from
Amino Acid Occurrence Frequencies:
20.51
Aliphatic Index:
78.26
Instability Index:
30.19
Isoelectric Point:
4.69
Secondary Structure Information
Secondary Structure features
% Number of Residues in Helices
27.59
% Number of Residues in Strands
8.16
% Number of Residues in Coils
64.23
Structural Difficulty(SD) Index: 12.94
Secondary Structure Cartoon Form (PSIPRED)
Conf
9
5
8
9
9
9
9
8
5
7
6
5
7
8
9
9
9
9
9
9
9
9
9
9
9
9
9
9
6
8
9
9
9
8
8
8
8
8
7
6
5
6
6
7
8
7
5
5
5
5
5
4
4
4
5
7
8
8
8
7
Cart
C
C
E
E
E
E
E
E
E
C
C
C
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
Pred
C
1
C
2
E
3
E
4
E
5
E
6
E
7
E
8
E
9
C
10
C
11
C
12
H
13
H
14
H
15
H
16
H
17
H
18
H
19
H
20
H
21
H
22
H
23
H
24
H
25
H
26
H
27
H
28
C
29
C
30
C
31
C
32
C
33
C
34
C
35
C
36
C
37
C
38
C
39
C
40
C
41
C
42
C
43
C
44
C
45
C
46
C
47
C
48
C
49
C
50
C
51
C
52
C
53
C
54
C
55
C
56
C
57
C
58
C
59
C
60
AA
M
1
R
2
E
3
V
4
I
5
S
6
I
7
H
8
V
9
G
10
Q
11
A
12
G
13
I
14
Q
15
V
16
G
17
N
18
A
19
C
20
W
21
E
22
L
23
F
24
C
25
L
26
E
27
H
28
G
29
I
30
Q
31
P
32
D
33
G
34
Q
35
M
36
P
37
S
38
D
39
K
40
A
41
A
42
R
43
A
44
N
45
D
46
D
47
A
48
F
49
N
50
T
51
F
52
F
53
S
54
E
55
T
56
G
57
A
58
G
59
K
60
Conf
7
5
6
7
7
7
7
5
6
8
9
8
7
4
5
4
4
4
4
5
8
8
8
8
8
8
8
9
7
6
6
5
5
5
7
7
7
7
7
7
7
7
7
6
6
5
4
4
4
4
4
6
7
8
8
8
8
9
9
9
Cart
C
E
E
E
E
E
E
E
C
C
C
C
C
E
E
E
H
H
H
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
H
H
H
H
H
H
H
H
H
H
Pred
C
61
E
62
E
63
E
64
E
65
E
66
E
67
E
68
C
69
C
70
C
71
C
72
C
73
E
74
E
75
E
76
H
77
H
78
H
79
C
80
C
81
C
82
C
83
C
84
C
85
C
86
C
87
C
88
C
89
C
90
C
91
C
92
C
93
C
94
C
95
C
96
C
97
C
98
C
99
C
100
C
101
C
102
C
103
C
104
C
105
C
106
C
107
C
108
C
109
C
110
H
111
H
112
H
113
H
114
H
115
H
116
H
117
H
118
H
119
H
120
AA
H
61
V
62
P
63
R
64
C
65
V
66
F
67
V
68
D
69
L
70
E
71
P
72
T
73
V
74
V
75
D
76
E
77
V
78
R
79
T
80
G
81
T
82
Y
83
R
84
Q
85
L
86
F
87
H
88
P
89
E
90
Q
91
L
92
I
93
S
94
G
95
K
96
E
97
D
98
A
99
A
100
N
101
N
102
F
103
A
104
R
105
G
106
H
107
Y
108
T
109
I
110
G
111
K
112
E
113
V
114
I
115
D
116
V
117
C
118
L
119
D
120
Conf
9
9
9
9
8
8
8
6
8
8
8
7
7
8
5
7
8
8
7
5
6
7
8
8
8
9
8
8
6
5
7
8
9
9
9
9
9
9
8
7
6
8
8
6
6
7
8
8
8
8
6
6
8
8
8
8
7
8
7
6
Cart
H
H
H
H
H
H
H
H
C
C
C
C
C
C
E
E
E
E
E
E
C
C
C
C
C
C
C
C
C
H
H
H
H
H
H
H
H
H
H
H
C
C
C
C
E
E
E
E
E
E
E
C
C
C
C
C
C
C
C
C
Pred
H
121
H
122
H
123
H
124
H
125
H
126
H
127
H
128
C
129
C
130
C
131
C
132
C
133
C
134
E
135
E
136
E
137
E
138
E
139
E
140
C
141
C
142
C
143
C
144
C
145
C
146
C
147
C
148
C
149
H
150
H
151
H
152
H
153
H
154
H
155
H
156
H
157
H
158
H
159
H
160
C
161
C
162
C
163
C
164
E
165
E
166
E
167
E
168
E
169
E
170
E
171
C
172
C
173
C
174
C
175
C
176
C
177
C
178
C
179
C
180
AA
R
121
I
122
R
123
K
124
L
125
A
126
D
127
N
128
C
129
T
130
G
131
L
132
Q
133
G
134
F
135
L
136
M
137
F
138
S
139
A
140
V
141
G
142
G
143
G
144
T
145
G
146
S
147
G
148
F
149
G
150
C
151
L
152
M
153
L
154
E
155
R
156
L
157
S
158
V
159
D
160
Y
161
G
162
K
163
K
164
S
165
K
166
L
167
N
168
F
169
C
170
C
171
W
172
P
173
S
174
P
175
Q
176
V
177
S
178
T
179
A
180
Conf
6
6
7
7
7
7
5
5
6
6
6
6
6
5
5
4
4
5
4
4
5
5
4
4
4
4
6
8
9
9
9
9
9
9
8
7
4
6
6
7
8
8
8
7
5
4
5
7
7
8
8
8
8
7
6
5
4
5
6
6
Cart
C
C
C
C
C
C
C
H
H
H
H
H
H
H
H
H
C
C
C
E
E
E
E
C
C
H
H
H
H
H
H
H
H
H
H
H
H
C
C
C
C
C
C
C
C
C
H
H
H
H
H
H
H
H
H
H
H
C
C
C
Pred
C
181
C
182
C
183
C
184
C
185
C
186
C
187
H
188
H
189
H
190
H
191
H
192
H
193
H
194
H
195
H
196
C
197
C
198
C
199
E
200
E
201
E
202
E
203
C
204
C
205
H
206
H
207
H
208
H
209
H
210
H
211
H
212
H
213
H
214
H
215
H
216
H
217
C
218
C
219
C
220
C
221
C
222
C
223
C
224
C
225
C
226
H
227
H
228
H
229
H
230
H
231
H
232
H
233
H
234
H
235
H
236
H
237
C
238
C
239
C
240
AA
V
181
V
182
E
183
P
184
Y
185
N
186
S
187
V
188
L
189
S
190
T
191
H
192
S
193
L
194
L
195
E
196
H
197
T
198
D
199
V
200
A
201
I
202
M
203
L
204
D
205
N
206
E
207
A
208
I
209
Y
210
D
211
I
212
C
213
K
214
K
215
N
216
L
217
D
218
I
219
E
220
R
221
P
222
T
223
Y
224
T
225
N
226
L
227
N
228
R
229
L
230
I
231
A
232
Q
233
V
234
I
235
S
236
S
237
L
238
T
239
A
240
Conf
6
7
8
8
8
7
6
6
7
6
4
6
6
7
7
7
7
5
8
8
8
8
7
5
5
4
5
6
6
6
7
8
8
8
7
6
6
4
5
6
5
5
5
5
5
7
8
9
9
9
9
9
9
8
8
6
5
5
5
4
Cart
C
C
C
C
C
C
C
C
C
C
C
H
H
H
H
H
H
H
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
H
H
H
H
H
H
C
C
C
H
H
H
H
H
H
H
H
H
H
H
H
H
Pred
C
241
C
242
C
243
C
244
C
245
C
246
C
247
C
248
C
249
C
250
C
251
H
252
H
253
H
254
H
255
H
256
H
257
H
258
C
259
C
260
C
261
C
262
C
263
C
264
C
265
C
266
C
267
C
268
C
269
C
270
C
271
C
272
C
273
C
274
C
275
C
276
C
277
C
278
H
279
H
280
H
281
H
282
H
283
H
284
C
285
C
286
C
287
H
288
H
289
H
290
H
291
H
292
H
293
H
294
H
295
H
296
H
297
H
298
H
299
H
300
AA
S
241
L
242
R
243
F
244
D
245
G
246
A
247
L
248
N
249
V
250
D
251
V
252
T
253
E
254
F
255
Q
256
T
257
N
258
L
259
V
260
P
261
Y
262
P
263
R
264
I
265
H
266
F
267
M
268
L
269
S
270
S
271
Y
272
A
273
P
274
V
275
V
276
S
277
A
278
E
279
K
280
A
281
Y
282
H
283
E
284
Q
285
L
286
S
287
V
288
S
289
E
290
I
291
T
292
N
293
S
294
A
295
F
296
E
297
P
298
A
299
N
300
Conf
5
5
5
5
6
9
9
9
8
8
6
8
9
9
9
9
9
9
8
5
9
9
9
8
6
7
8
8
9
9
9
9
9
9
8
8
7
5
6
6
5
5
4
5
6
7
8
8
8
8
5
6
7
6
6
5
8
9
9
7
Cart
C
C
C
C
C
C
C
C
C
C
H
H
H
H
H
H
H
H
H
H
C
C
C
C
H
H
H
H
H
H
H
H
H
H
H
H
H
H
C
C
C
C
C
C
C
C
C
C
C
C
C
E
E
E
E
C
C
C
C
C
Pred
C
301
C
302
C
303
C
304
C
305
C
306
C
307
C
308
C
309
C
310
H
311
H
312
H
313
H
314
H
315
H
316
H
317
H
318
H
319
H
320
C
321
C
322
C
323
C
324
H
325
H
326
H
327
H
328
H
329
H
330
H
331
H
332
H
333
H
334
H
335
H
336
H
337
H
338
C
339
C
340
C
341
C
342
C
343
C
344
C
345
C
346
C
347
C
348
C
349
C
350
C
351
E
352
E
353
E
354
E
355
C
356
C
357
C
358
C
359
C
360
AA
M
301
M
302
A
303
K
304
C
305
D
306
P
307
R
308
H
309
G
310
K
311
Y
312
M
313
A
314
C
315
C
316
L
317
M
318
Y
319
R
320
G
321
D
322
V
323
V
324
P
325
K
326
D
327
V
328
N
329
A
330
A
331
V
332
A
333
T
334
I
335
K
336
T
337
K
338
R
339
T
340
I
341
Q
342
F
343
V
344
D
345
W
346
C
347
P
348
T
349
G
350
F
351
K
352
C
353
G
354
I
355
N
356
Y
357
Q
358
P
359
P
360
Conf
5
5
8
8
8
8
7
7
7
8
8
6
5
6
7
7
6
5
7
8
7
7
8
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
8
7
6
5
3
4
3
3
4
4
6
8
8
8
7
7
8
9
9
9
9
Cart
E
C
C
C
C
C
C
C
C
C
C
C
E
E
E
E
E
C
C
C
C
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
C
C
E
E
E
E
E
C
C
C
C
C
C
H
H
H
H
H
H
Pred
E
361
C
362
C
363
C
364
C
365
C
366
C
367
C
368
C
369
C
370
C
371
C
372
E
373
E
374
E
375
E
376
E
377
C
378
C
379
C
380
C
381
H
382
H
383
H
384
H
385
H
386
H
387
H
388
H
389
H
390
H
391
H
392
H
393
H
394
H
395
H
396
H
397
H
398
H
399
H
400
H
401
C
402
C
403
E
404
E
405
E
406
E
407
E
408
C
409
C
410
C
411
C
412
C
413
C
414
H
415
H
416
H
417
H
418
H
419
H
420
AA
T
361
V
362
V
363
P
364
G
365
G
366
D
367
L
368
A
369
K
370
V
371
M
372
R
373
A
374
V
375
C
376
M
377
I
378
S
379
N
380
S
381
T
382
A
383
I
384
A
385
E
386
V
387
F
388
S
389
R
390
M
391
D
392
Q
393
K
394
F
395
D
396
L
397
M
398
Y
399
A
400
K
401
R
402
A
403
F
404
V
405
H
406
W
407
Y
408
V
409
G
410
E
411
G
412
M
413
E
414
E
415
G
416
E
417
F
418
S
419
E
420
Conf
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
7
7
5
5
5
5
5
5
5
5
6
6
6
6
6
6
7
7
7
7
6
6
7
7
7
7
8
8
8
8
9
9
Cart
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
C
C
C
C
C
C
C
C
C
C
C
C
C
C
Pred
H
421
H
422
H
423
H
424
H
425
H
426
H
427
H
428
H
429
H
430
H
431
H
432
H
433
H
434
H
435
H
436
H
437
H
438
H
439
C
440
C
441
C
442
C
443
C
444
C
445
C
446
C
447
C
448
C
449
C
450
C
451
C
452
C
453
AA
A
421
R
422
E
423
D
424
L
425
A
426
A
427
L
428
E
429
K
430
D
431
Y
432
E
433
E
434
V
435
G
436
I
437
E
438
T
439
N
440
E
441
G
442
E
443
G
444
E
445
D
446
E
447
G
448
Y
449
E
450
A
451
D
452
Y
453
Legend:
Helix
Strand
Coil
Conf:
-
+
Confidence of prediction
Cart:
3-state assignment cartoon
Pred:
3-state prediction
AA:
Target Sequence
Tertiary Structural Information
Models
BhageerathH
+
RaptorX
I-TASSER
View Structure in full screen
ProtSAV
PROCHECK
Verify3D
ERRAT
Naccess
Ligand Binding Site Information
Models
BhageerathH
+
RaptorX
I-TASSER
Ligand Binding Site
Pocket 1
Pocket 2
Pocket 3
Pocket 4
ActiveSite
FPocket
LigSite
Functional Annotations
InterPro
LocTree
ProBiS
SHIFTER
UniProt
GO:0007017
GO:0005525
GO:0003924
GO:0005200
GO:0005200
GO:0005874
GO:0003924
GO:0005525
GO:0005525
GO:0003924
GO:0003924
GO:0007017
GO:0007017
GO:0003924
--
GO:0003924
--
--
--
--
Pathway Annotation
Phagosome
