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SCFBio
PvP01_0617600
Protein Name: Derlin
Sequence Information
Sequence Length:
262
Download Sequence
Sequence:
1
MDISGPEVWYGNLPNVTKYLITLIFLVTLLITCNLLNVVYLLLDWNLIYNNYQIWRMFFNFLYVGKFSLSWVFFMSLLAQ
80
81
FSSSLEKNAVFSTPGSYLYFITIQCTFLSLISILFYWPRGYPFLGNSLLFAIIYYWSRREAWSQVSIYFFTVKGYQLPFA
160
161
LIFLHLIMGQSLWVDIMGLMSGHIYYFFRELLPREGGPNLLEKTPKIFDKIMMKLREFRLNQGIRGNFSRYGYRSVSDSR
240
241
TPNSAGPTRRVFIGRGVRLGDN
262
Amino Acid Composition
Frequency Percentage
15
14
13
12
11
10
9
8
7
6
5
4
3
2
1
2.29
6
ALA
6.10
16
ARG
5.72
15
ASN
2.29
6
ASP
.76
2
CYS
2.67
7
GLU
2.67
7
GLN
.76
2
GLY
.76
2
HIS
8.01
21
ILE
14.12
37
LEU
3.05
8
LYS
3.05
8
MET
9.16
24
PHE
4.19
11
PRO
8.39
22
SER
4.19
11
THR
3.05
8
TRP
6.87
18
TYR
5.34
14
VAL
Amino Acid
External Database Links :
Molecular Weight:
30791
Sum of Absolute Deviation from
Amino Acid Occurrence Frequencies:
51.13
Aliphatic Index:
104.06
Instability Index:
27.23
Isoelectric Point:
9.92
Secondary Structure Information
Secondary Structure features
% Number of Residues in Helices
51.14
% Number of Residues in Strands
3.43
% Number of Residues in Coils
45.41
Structural Difficulty(SD) Index: 51.14
Secondary Structure Cartoon Form (PSIPRED)
Conf
9
8
7
6
7
9
9
9
9
9
9
8
9
9
7
9
8
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
7
9
8
7
7
4
5
6
7
7
7
5
8
8
8
8
7
6
5
6
5
4
3
5
4
4
4
4
Cart
C
C
C
C
H
H
H
H
H
H
H
H
C
C
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
C
C
C
C
C
E
E
E
E
E
C
H
H
H
H
H
H
C
C
C
C
E
E
H
H
H
H
Pred
C
1
C
2
C
3
C
4
H
5
H
6
H
7
H
8
H
9
H
10
H
11
H
12
C
13
C
14
H
15
H
16
H
17
H
18
H
19
H
20
H
21
H
22
H
23
H
24
H
25
H
26
H
27
H
28
H
29
H
30
H
31
H
32
H
33
C
34
C
35
C
36
C
37
C
38
E
39
E
40
E
41
E
42
E
43
C
44
H
45
H
46
H
47
H
48
H
49
H
50
C
51
C
52
C
53
C
54
E
55
E
56
H
57
H
58
H
59
H
60
AA
M
1
D
2
I
3
S
4
G
5
P
6
E
7
V
8
W
9
Y
10
G
11
N
12
L
13
P
14
N
15
V
16
T
17
K
18
Y
19
L
20
I
21
T
22
L
23
I
24
F
25
L
26
V
27
T
28
L
29
L
30
I
31
T
32
C
33
N
34
L
35
L
36
N
37
V
38
V
39
Y
40
L
41
L
42
L
43
D
44
W
45
N
46
L
47
I
48
Y
49
N
50
N
51
Y
52
Q
53
I
54
W
55
R
56
M
57
F
58
F
59
N
60
Conf
4
4
3
6
8
8
7
6
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
8
5
6
7
8
9
8
7
5
5
7
8
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
8
7
5
5
6
7
Cart
H
H
C
C
C
C
C
C
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
C
C
C
C
C
C
C
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
C
C
C
Pred
H
61
H
62
C
63
C
64
C
65
C
66
C
67
C
68
H
69
H
70
H
71
H
72
H
73
H
74
H
75
H
76
H
77
H
78
H
79
H
80
H
81
H
82
H
83
H
84
H
85
H
86
H
87
C
88
C
89
C
90
C
91
C
92
C
93
C
94
H
95
H
96
H
97
H
98
H
99
H
100
H
101
H
102
H
103
H
104
H
105
H
106
H
107
H
108
H
109
H
110
H
111
H
112
H
113
H
114
H
115
H
116
H
117
C
118
C
119
C
120
AA
F
61
L
62
Y
63
V
64
G
65
K
66
F
67
S
68
L
69
S
70
W
71
V
72
F
73
F
74
M
75
S
76
L
77
L
78
A
79
Q
80
F
81
S
82
S
83
S
84
L
85
E
86
K
87
N
88
A
89
V
90
F
91
S
92
T
93
P
94
G
95
S
96
Y
97
L
98
Y
99
F
100
I
101
T
102
I
103
Q
104
C
105
T
106
F
107
L
108
S
109
L
110
I
111
S
112
I
113
L
114
F
115
Y
116
W
117
P
118
R
119
G
120
Conf
6
4
3
4
5
7
8
9
9
9
9
9
9
9
9
9
8
6
5
7
9
9
5
8
9
9
9
9
9
9
9
7
6
5
7
9
9
9
9
9
9
9
9
9
9
9
8
5
8
8
6
8
9
9
9
9
9
9
9
9
Cart
C
C
C
C
H
H
H
H
H
H
H
H
H
H
H
H
H
H
H
C
C
C
C
E
E
E
E
E
E
E
E
E
C
C
H
H
H
H
H
H
H
H
H
H
H
H
H
H
C
C
C
H
H
H
H
H
H
H
H
H
Pred
C
121
C
122
C
123
C
124
H
125
H
126
H
127
H
128
H
129
H
130
H
131
H
132
H
133
H
134
H
135
H
136
H
137
H
138
H
139
C
140
C
141
C
142
C
143
E
144
E
145
E
146
E
147
E
148
E
149
E
150
E
151
E
152
C
153
C
154
H
155
H
156
H
157
H
158
H
159
H
160
H
161
H
162
H
163
H
164
H
165
H
166
H
167
H
168
C
169
C
170
C
171
H
172
H
173
H
174
H
175
H
176
H
177
H
178
H
179
H
180
AA
Y
121
P
122
F
123
L
124
G
125
N
126
S
127
L
128
L
129
F
130
A
131
I
132
I
133
Y
134
Y
135
W
136
S
137
R
138
R
139
E
140
A
141
W
142
S
143
Q
144
V
145
S
146
I
147
Y
148
F
149
F
150
T
151
V
152
K
153
G
154
Y
155
Q
156
L
157
P
158
F
159
A
160
L
161
I
162
F
163
L
164
H
165
L
166
I
167
M
168
G
169
Q
170
S
171
L
172
W
173
V
174
D
175
I
176
M
177
G
178
L
179
M
180
Conf
9
9
9
9
9
9
9
9
9
8
7
6
6
7
7
8
9
8
8
7
6
7
8
9
6
9
9
9
9
9
8
7
5
7
7
7
7
7
7
7
7
7
8
7
8
8
7
7
7
7
8
8
8
8
8
8
8
8
8
8
Cart
H
H
H
H
H
H
H
H
H
H
H
C
C
C
C
C
C
C
C
C
C
C
C
C
C
H
H
H
H
H
H
H
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
Pred
H
181
H
182
H
183
H
184
H
185
H
186
H
187
H
188
H
189
H
190
H
191
C
192
C
193
C
194
C
195
C
196
C
197
C
198
C
199
C
200
C
201
C
202
C
203
C
204
C
205
H
206
H
207
H
208
H
209
H
210
H
211
H
212
C
213
C
214
C
215
C
216
C
217
C
218
C
219
C
220
C
221
C
222
C
223
C
224
C
225
C
226
C
227
C
228
C
229
C
230
C
231
C
232
C
233
C
234
C
235
C
236
C
237
C
238
C
239
C
240
AA
S
181
G
182
H
183
I
184
Y
185
Y
186
F
187
F
188
R
189
E
190
L
191
L
192
P
193
R
194
E
195
G
196
G
197
P
198
N
199
L
200
L
201
E
202
K
203
T
204
P
205
K
206
I
207
F
208
D
209
K
210
I
211
M
212
M
213
K
214
L
215
R
216
E
217
F
218
R
219
L
220
N
221
Q
222
G
223
I
224
R
225
G
226
N
227
F
228
S
229
R
230
Y
231
G
232
Y
233
R
234
S
235
V
236
S
237
D
238
S
239
R
240
Conf
8
8
8
8
8
8
8
8
8
8
8
8
8
8
8
8
8
8
8
8
8
8
7
7
8
8
8
8
8
8
7
7
6
6
7
7
7
7
8
8
9
9
9
9
Cart
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
C
Pred
C
241
C
242
C
243
C
244
C
245
C
246
C
247
C
248
C
249
C
250
C
251
C
252
C
253
C
254
C
255
C
256
C
257
C
258
C
259
C
260
C
261
C
262
AA
T
241
P
242
N
243
S
244
A
245
G
246
P
247
T
248
R
249
R
250
V
251
F
252
I
253
G
254
R
255
G
256
V
257
R
258
L
259
G
260
D
261
N
262
Legend:
Helix
Strand
Coil
Conf:
-
+
Confidence of prediction
Cart:
3-state assignment cartoon
Pred:
3-state prediction
AA:
Target Sequence
Tertiary Structural Information
Models
BhageerathH
+
RaptorX
I-TASSER
View Structure in full screen
ProtSAV
PROCHECK
Verify3D
ERRAT
Naccess
Ligand Binding Site Information
Models
BhageerathH
+
RaptorX
I-TASSER
Ligand Binding Site
Pocket 1
Pocket 2
Pocket 3
Pocket 4
ActiveSite
FPocket
LigSite
Functional Annotations
InterPro
LocTree
ProBiS
SHIFTER
UniProt
GO:0030176
GO:0005634
GO:0004252
GO:0030968
GO:0005789
GO:0030433
GO:0005737
GO:0006508
--
GO:0016021
GO:0030968
GO:0005789
GO:0016021
--
--
--
GO:0016021
--
--
--
Pathway Annotation
Protein Processing in Endoplasmic Reticulum
