Reviewed
Homo Sapiens (Human) [TaxID: 9606]
POL[Gene ID: 2715933 ]
DNA polymerase (EC 2.7.7.7)
Human Adenovirus F Serotype 40 (HAdV-40) (Human Adenovirus 40)
Viruses> DsDNA Viruses> No RNA Stage> Adenoviridae> Mastadenovirus> Human Mastadenovirus F> Human Adenovirus F Serotype 40 (HAdV-40) (Human Adenovirus 40)
Various pathway(s) in which protein is involved
Not Available
MALVPSPRAGGFLPAETHSGPQPPRRRVRQSTAGAAPTATRAPRRRAATASPGEPPSTTASGRPPAANNVSLTPNSRLRGTIVAPRGQGLLYAIDTATNS
PMEIKFHRRLASALTRLLQVNLRSVPADLNEAFLDSLDSSQIRTLALKLKVPRVEVWTCGSRGVVVPSIIHPQQERAGAEEGDEGERQDTEDFLNFPLRF
LVRGRQVHLIQEMQSVQRCEYCARFYKYQHECTVRRRDFYFHHINAHSSGWWQKINFFPIGSHPRVERLFVTYDVETYTWMGAFGKQLVPFMLVMHLSGE
EALVKEACRLACELQWDTWGNDERTFYVVTPEKLAVGKKFREYRNRLQAHFALQLWRGFLAANPQLAEWACLEMGLFSPDYLTYEELQKAPKLQGRPRFL
ELYIVGHNINGFDEIVLAAQVINNRSDVPGPFKITRNFMPRAGKILFNDITFALPNPSSKKRTDYRLWEQGACDDSDFKYQFLKVMVRDTFALTHTSLRK
AAQAYTLPVEKGCCPYKAVNEFYMLGSYRADERGFPAEDYWKDREEYLLNRELWEKKQCPHYDLVRETLDYCALDVLVTAALVQKLRESYAQFIRDAVGL
PEASFNVFQRPTISSNSHAIFRQILYRTVKPQRSDLGGSLLAPSHEMYDYVRASIRGGRCYPTYIGVLREPLYVYDICGMYASALTHPMPWGFPLNPYER
ALAVRDWEHALLQVGTPIDYFNRTLLPGIFTIDADPPPENLLDVLPPLCSRKGGRLCWTNEPLRGEVVTSVDLITLHNRGWHVRLLPDERATVFPEWRCV
AKEYVHLNITAKERADREKNQTLRSIAKLLSNALYGSFATKLDNKKIVFSDQMDSATIKSIAAGQINIKSTSFVETDTLSAEVMPTFQRAYSPEQLAVVH
SDAEESDEEPGHAPFYTPTHKPNDHVTYTYKPITFMDAEEDDLCLHTLEKVDPLVENNRYPSQIASFVLAWTRAFVSEWSEILYAEDRGTPLEQRTLKSV
YGDTDSLFVTEAGYRLMETRGKKRIKKHGGNLVFDPKHPELAWLVECETVCAQCGADAYSPESVFLAPKLYALKCLRCPSCQQISKGKLRAKGHAAETLN
YDLMLKCYLADFQGEDARFHTSRMSLKRTLASAQPGARPFTVTETNLTRTLRPWKDITLAPLDAHRLVPYSQSRPNPRNQEVCWIEMP
PMEIKFHRRLASALTRLLQVNLRSVPADLNEAFLDSLDSSQIRTLALKLKVPRVEVWTCGSRGVVVPSIIHPQQERAGAEEGDEGERQDTEDFLNFPLRF
LVRGRQVHLIQEMQSVQRCEYCARFYKYQHECTVRRRDFYFHHINAHSSGWWQKINFFPIGSHPRVERLFVTYDVETYTWMGAFGKQLVPFMLVMHLSGE
EALVKEACRLACELQWDTWGNDERTFYVVTPEKLAVGKKFREYRNRLQAHFALQLWRGFLAANPQLAEWACLEMGLFSPDYLTYEELQKAPKLQGRPRFL
ELYIVGHNINGFDEIVLAAQVINNRSDVPGPFKITRNFMPRAGKILFNDITFALPNPSSKKRTDYRLWEQGACDDSDFKYQFLKVMVRDTFALTHTSLRK
AAQAYTLPVEKGCCPYKAVNEFYMLGSYRADERGFPAEDYWKDREEYLLNRELWEKKQCPHYDLVRETLDYCALDVLVTAALVQKLRESYAQFIRDAVGL
PEASFNVFQRPTISSNSHAIFRQILYRTVKPQRSDLGGSLLAPSHEMYDYVRASIRGGRCYPTYIGVLREPLYVYDICGMYASALTHPMPWGFPLNPYER
ALAVRDWEHALLQVGTPIDYFNRTLLPGIFTIDADPPPENLLDVLPPLCSRKGGRLCWTNEPLRGEVVTSVDLITLHNRGWHVRLLPDERATVFPEWRCV
AKEYVHLNITAKERADREKNQTLRSIAKLLSNALYGSFATKLDNKKIVFSDQMDSATIKSIAAGQINIKSTSFVETDTLSAEVMPTFQRAYSPEQLAVVH
SDAEESDEEPGHAPFYTPTHKPNDHVTYTYKPITFMDAEEDDLCLHTLEKVDPLVENNRYPSQIASFVLAWTRAFVSEWSEILYAEDRGTPLEQRTLKSV
YGDTDSLFVTEAGYRLMETRGKKRIKKHGGNLVFDPKHPELAWLVECETVCAQCGADAYSPESVFLAPKLYALKCLRCPSCQQISKGKLRAKGHAAETLN
YDLMLKCYLADFQGEDARFHTSRMSLKRTLASAQPGARPFTVTETNLTRTLRPWKDITLAPLDAHRLVPYSQSRPNPRNQEVCWIEMP
1188
Not Available
Not Available
01-02-1996
Inferred from homology
| Amino Acid | Count | % Frequency | Amino Acid | Count | % Frequency |
|---|---|---|---|---|---|
| Alanine (A) | Leucine (L) | ||||
| Arginine (R) | Lysine (K) | ||||
| Asparagine (N) | Methionine (M) | ||||
| Aspartic Acid (D) | Phenylalanine (F) | ||||
| Cysteine (C) | Proline (P) | ||||
| Glutamine (Q) | Serine (S) | ||||
| Glutamic Acid (E) | Threonine (T) | ||||
| Glycine (G) | Tryptophan (W) | ||||
| Histidine (H) | Tyrosine (Y) | ||||
| Isoleucine (I) | Valine (V) |
| % Number of Residues in Helices | % Number of Residues in Strands | % Number of Residues in Coils |
|---|---|---|
Eukaryotic-type DNA polymerase involved in viral genomic replication. DNA synthesis is protein primed, and acts in a strand displacement replication. Assembles in complex with viral pTP, DBP, host NFIA and host POU2F1/OCT1 on viral origin of replication. The polymerase covalently transfers dCMP onto pTP, thereby initiating complementary strand synthesis.
2.7.7.7
Host nucleus , .
Not Available
Not Available
Predicted/Modelled
Not Available
Not Available
Protein couldn't be modeled using I-Tasser and Raptor X because of length constraints of the software.
Not Available
- Million Molecules
Best 20 Hit molecules
Not Available