Results | viHumans

UniProt ID

P21186

Status

Reviewed

Host

Homo Sapiens (Human) [TaxID: 9606]

Gene Name

N NP[Gene ID: 1489766 ]

Protein Name

Nucleoprotein (Nucleocapsid protein) (NP) (Protein N)

Organism Name

Mumps Virus (strain Miyahara Vaccine) (MuV)

Taxonomic Lineage

Viruses> SsRNA Viruses> SsRNA Negative-strand Viruses> Mononegavirales> Paramyxoviridae> Rubulavirus> Mumps Rubulavirus> Mumps Virus (strain Miyahara Vaccine) (MuV)

RefSeq

NC_002200.1 ; AB040874.1

PubMed ID

1693800 ; 1585659

Pathways Involved

Various pathway(s) in which protein is involved

KEGG

vg:1489766

Reactome

Not Available

Sequence

							MSSVLKAFERFTIEQELQDRGEEGSIPPETLKSAVKVFVINTPNPTTRYHMLNFCLRIICSQNARASHRVGALITLFSLPSAGMQNHIRLADRSPEAQIE
RCEIDGFEPGTYRLIPNARANLTANEIAAYALLADDLPPTINNGTPYVHADVEGQPCDEIEQFLDRCYSVLIQAWVMVCKCMTAYDQPAGSADRRFAKYQ
QQGRLEARYMLQPEAQRLIQTAIRKSLVVRQYLTFELQLARRQGLLSNRYYAMVGDIGKYIENSGLTAFFLTLKYALGTKWSPLSLAAFTGELTKLRSLM
MLYRDLGEQARYLALLEAPQIMDFAPGGYPLIFSYAMGVGTVLDVQMRNYTYARPFLNGYYFQIGVETARRQQGTVDNRVADDLGLTPEQRTEVTQLIDR
LARGRGAGIPGGPVNPFVPPVQQQQPAAAYEDIPALEESDDDGDEDGGAGFQNGAQAPAARQGGQNDFRVQPLQDPIQAQLFMPLYPQVSNIPNHQNHQI
NRIGGMEHQDLLRYNENGDSQQDARGEHGNTFPNNPNQNAQSQVGDWDE
						

Length

549

Alternate Sequence

Not Available

Non-standard residue

Not Available

Date of last Sequence modification

01-05-1991

Protein Existence

Inferred from homology

Amino Acid composition

Amino Acid	Count	% Frequency	Amino Acid	Count	% Frequency
Alanine (A)			Leucine (L)
Arginine (R)			Lysine (K)
Asparagine (N)			Methionine (M)
Aspartic Acid (D)			Phenylalanine (F)
Cysteine (C)			Proline (P)
Glutamine (Q)			Serine (S)
Glutamic Acid (E)			Threonine (T)
Glycine (G)			Tryptophan (W)
Histidine (H)			Tyrosine (Y)
Isoleucine (I)			Valine (V)

Sum of Absolute Deviation from Amino Acid Occurrence Frequencies

Aliphatic Index

Instability Index

Secondary Structure features

% Number of Residues in Helices	% Number of Residues in Strands	% Number of Residues in Coils

Structural Difficulty(SD) index

Role(s)

Encapsidates the genome, protecting it from nucleases. The nucleocapsid (NC) has a helical structure, approximately 20 nm in diameter, with a hollow central cavity approximately 5 nm in diameter. The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication. During replication, encapsidation by N is coupled to RNA synthesis and all replicative products are resistant to nucleases (By similarity).

EC

Not Available

Experimentally known GO terms

GO:0003723 ; GO:0005198 ; GO:0019013 ; GO:0019029 ; GO:0030430

Subcellular Location

Virion . Host cytoplasm.

Domain(s)

Not Available

Motif(s)

Not Available

Methods of 3D structure generation

Predicted/Modelled

Experimetally known structure

Not Available

Active Site(s)

Not Available

Predicted 3D Structures

Protein couldn't be modeled using I-Tasser and Raptor X because of length constraints of the software.

Experimentally known Ligand(s)

Not Available

Virtually Screened Ligands

Virtual screening has been performed using RASPD

						Million Molecules

					
Best 20 Hit molecules 
Not Available