Results | viHumans

UniProt ID

P20716

Status

Reviewed

Host

Homo Sapiens (Human) [TaxID: 9606]

Gene Name

SH

Protein Name

Small hydrophobic protein

Organism Name

Mumps Virus (strain Urabe Vaccine AM9) (MuV)

Taxonomic Lineage

Viruses> SsRNA Viruses> SsRNA Negative-strand Viruses> Mononegavirales> Paramyxoviridae> Rubulavirus> Mumps Rubulavirus> Mumps Virus Genotype B> Mumps Virus Strain Urabe> Mumps Virus (strain Urabe Vaccine AM9) (MuV)

RefSeq

NC_002200.1 ; AB040874.1

PubMed ID

1993881 ;

Pathways Involved

Various pathway(s) in which protein is involved

KEGG

Not Available

Reactome

Not Available

Sequence

							MPAIQPPLYPTFLLLILLSLIVTLYVWIISTITYKTVVRHAALYQRSFFRWSFDHSL
						

Length

57

Alternate Sequence

Not Available

Non-standard residue

Not Available

Date of last Sequence modification

01-02-1991

Protein Existence

Inferred from homology

Amino Acid composition

Amino Acid	Count	% Frequency	Amino Acid	Count	% Frequency
Alanine (A)			Leucine (L)
Arginine (R)			Lysine (K)
Asparagine (N)			Methionine (M)
Aspartic Acid (D)			Phenylalanine (F)
Cysteine (C)			Proline (P)
Glutamine (Q)			Serine (S)
Glutamic Acid (E)			Threonine (T)
Glycine (G)			Tryptophan (W)
Histidine (H)			Tyrosine (Y)
Isoleucine (I)			Valine (V)

Sum of Absolute Deviation from Amino Acid Occurrence Frequencies

Aliphatic Index

Instability Index

Secondary Structure features

% Number of Residues in Helices	% Number of Residues in Strands	% Number of Residues in Coils

Structural Difficulty(SD) index

Role(s)

Plays a role in the inhibition of the host NF-kappa-B pathway. This inhibition occurs at the receptor level, by preventing the signaling of TNFR1 as well as IL-1R and TLR3.

EC

Not Available

Experimentally known GO terms

GO:0016021 ; GO:0020002 ; GO:0039644 ; GO:0055036

Subcellular Location

♦ Virion membrane
♦ Single-pass membrane protein . Host cell membrane
♦ Single-pass membrane protein .

Domain(s)

Not Available

Motif(s)

Not Available

Methods of 3D structure generation

Predicted/Modelled

Experimetally known structure

Not Available

Active Site(s)

Not Available

Predicted 3D Structures

Protein couldn't be modeled using I-Tasser and Raptor X because of length constraints of the software.

Experimentally known Ligand(s)

Not Available

Virtually Screened Ligands

Virtual screening has been performed using RASPD

						Million Molecules

					
Best 20 Hit molecules 
Not Available