Results | viHumans

UniProt ID

P16739

Status

Reviewed

Host

Homo Sapiens (Human) [TaxID: 9606]

Gene Name

UL119/UL118

Protein Name

Viral Fc-gamma receptor-like protein UL119 (gp68)

Organism Name

Human Cytomegalovirus (strain AD169) (HHV-5) (Human Herpesvirus 5)

Taxonomic Lineage

Viruses> DsDNA Viruses> No RNA Stage> Herpesvirales> Herpesviridae> Betaherpesvirinae> Cytomegalovirus> Human Cytomegalovirus (HHV-5) (Human Herpesvirus 5)> Human Cytomegalovirus (strain AD169) (HHV-5) (Human Herpesvirus 5)

RefSeq

Not Available

PubMed ID

2161319 ; 12163579 ; 12533697 ; 15452216 ; 18216124

Pathways Involved

Various pathway(s) in which protein is involved

KEGG

Not Available

Reactome

Not Available

Sequence

							MCSVLAIALVVALLGDMHPGVKSSTTSAVTSPSNTTVTSTTSISTSNNVTSAVTTTVQTSTSSASTSVIATTQKEGHLYTVNCEASYSHDQVSLNATCKV
ILLNNTKNPDILSVTCYARTDCKGPFTQVGYLSAFPPDNEGKLHLSYNATAQELLISGLRPQETTEYTCSFFSWGRHHNATWDLFTYPIYAVYGTRLNAT
TMRVRVLLQEHEHCLLNGSSLYHPNSTVHLHQGNQLIPPWNISNVTYNGQRLREFVFYLNGTYTVVRLHVQIAGRSFTTTYVFIKSDPLFEDRLLAYGVL
AFLVFMVIILLYVTYMLARRRDWSYKRLEEPVEEKKHPVPYFKQW
						

Length

345

Alternate Sequence

Not Available

Non-standard residue

Not Available

Date of last Sequence modification

15-02-2005

Protein Existence

Evidence at transcript level

Amino Acid composition

Amino Acid	Count	% Frequency	Amino Acid	Count	% Frequency
Alanine (A)			Leucine (L)
Arginine (R)			Lysine (K)
Asparagine (N)			Methionine (M)
Aspartic Acid (D)			Phenylalanine (F)
Cysteine (C)			Proline (P)
Glutamine (Q)			Serine (S)
Glutamic Acid (E)			Threonine (T)
Glycine (G)			Tryptophan (W)
Histidine (H)			Tyrosine (Y)
Isoleucine (I)			Valine (V)

Sum of Absolute Deviation from Amino Acid Occurrence Frequencies

Aliphatic Index

Instability Index

Secondary Structure features

% Number of Residues in Helices	% Number of Residues in Strands	% Number of Residues in Coils

Structural Difficulty(SD) index

Role(s)

Serves as a receptor for the Fc part of human IgG. May thus be involved in interfering with host Ig-mediated immune responses.

EC

Not Available

Experimentally known GO terms

GO:0016021 ; GO:0030683 ; GO:0055036 ; GO:0075528

Subcellular Location

♦ Virion membrane
♦ Single-pass type I membrane protein .

Domain(s)

DOMAIN 91 190 Ig-like V-type.

Motif(s)

Not Available

Methods of 3D structure generation

Predicted/Modelled

Experimetally known structure

Not Available

Active Site(s)

Not Available

Predicted 3D Structures

Protein couldn't be modeled using I-Tasser and Raptor X because of length constraints of the software.

Experimentally known Ligand(s)

Not Available

Virtually Screened Ligands

Virtual screening has been performed using RASPD

						Million Molecules

					
Best 20 Hit molecules 
Not Available