Results | viHumans

UniProt ID

P13293

Status

Reviewed

Host

Homo Sapiens (Human) [TaxID: 9606]

Gene Name

GJ US5[Gene ID: 1487357 ]

Protein Name

Envelope glycoprotein J

Organism Name

Human Herpesvirus 2 (strain HG52) (HHV-2) (Human Herpes Simplex Virus 2)

Taxonomic Lineage

Viruses> DsDNA Viruses> No RNA Stage> Herpesvirales> Herpesviridae> Alphaherpesvirinae> Simplexvirus> Human Herpesvirus 2 (HHV-2) (Human Herpes Simplex Virus 2)> Human Herpesvirus 2 (strain HG52) (HHV-2) (Human Herpes Simplex Virus 2)

RefSeq

Not Available

PubMed ID

3027242 ; 9499055

Pathways Involved

Various pathway(s) in which protein is involved

KEGG

vg:1487357

Reactome

Not Available

Sequence

							MDRYAVRTWGIVGILGCAAVGAAPTGPASDTTNATARLPTHPPLIRSGGFAVPLIVGGLCLMILGMACLLEVLRRLGRELARCCPHAGQFAP
						

Length

92

Alternate Sequence

Not Available

Non-standard residue

Not Available

Date of last Sequence modification

01-01-1990

Protein Existence

Inferred from homology

Amino Acid composition

Amino Acid	Count	% Frequency	Amino Acid	Count	% Frequency
Alanine (A)			Leucine (L)
Arginine (R)			Lysine (K)
Asparagine (N)			Methionine (M)
Aspartic Acid (D)			Phenylalanine (F)
Cysteine (C)			Proline (P)
Glutamine (Q)			Serine (S)
Glutamic Acid (E)			Threonine (T)
Glycine (G)			Tryptophan (W)
Histidine (H)			Tyrosine (Y)
Isoleucine (I)			Valine (V)

Sum of Absolute Deviation from Amino Acid Occurrence Frequencies

Aliphatic Index

Instability Index

Secondary Structure features

% Number of Residues in Helices	% Number of Residues in Strands	% Number of Residues in Coils

Structural Difficulty(SD) index

Role(s)

Inhibits host cell apoptosis. Induces an increase in reactive oxygen species (ROS) in the host cell (By similarity).

EC

Not Available

Experimentally known GO terms

GO:0016021 ; GO:0044167 ; GO:0044175 ; GO:0044178

Subcellular Location

♦ Host Golgi apparatus membrane
♦ Single-pass type I membrane protein . Host endoplasmic reticulum membrane
♦ Single-pass type I membrane protein . Host endosome membrane
♦ Single-pass type I membrane protein . Note=Localizes to the endoplasmic reticulum, trans-Golgi network, and early endosomes. .

Domain(s)

Not Available

Motif(s)

Not Available

Methods of 3D structure generation

Predicted/Modelled

Experimetally known structure

Not Available

Active Site(s)

Not Available

Predicted 3D Structures

Protein couldn't be modeled using I-Tasser and Raptor X because of length constraints of the software.

Experimentally known Ligand(s)

Not Available

Virtually Screened Ligands

Virtual screening has been performed using RASPD

						Million Molecules

					
Best 20 Hit molecules 
Not Available