viHumans
Reviewed
Homo Sapiens (Human) [TaxID: 9606]
ORF46
Tegument protein UL14 homolog
Varicella-zoster Virus (strain Dumas) (HHV-3) (Human Herpesvirus 3)
Viruses> DsDNA Viruses> No RNA Stage> Herpesvirales> Herpesviridae> Alphaherpesvirinae> Varicellovirus> Human Herpesvirus 3 (HHV-3) (Varicella-zoster Virus)> Varicella-zoster Virus (strain Dumas) (HHV-3) (Human Herpesvirus 3)
Various pathway(s) in which protein is involved
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MSGHTPTYASHRRNRVKLVEAHNRAGLFKERTLDLIRGGASVQDPAFVYAFTAAKEACADLNNQLRSAARIASVEQKIRDIQSKVEEQTSIQQILNTNRR
YIAPDFIRGLDKTEDDNTDNIDRLEDAVGPNIEHENHTWFGEDDEALLTQWMLTTHPPTSKYLQLQDLCVPTTIPTDMNQMQPQPISKNENPPTPHTDV
199
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01-07-1989
Inferred from homology
Amino Acid Count % Frequency Amino Acid Count % Frequency
Alanine (A) Leucine (L)
Arginine (R) Lysine (K)
Asparagine (N) Methionine (M)
Aspartic Acid (D) Phenylalanine (F)
Cysteine (C) Proline (P)
Glutamine (Q) Serine (S)
Glutamic Acid (E) Threonine (T)
Glycine (G) Tryptophan (W)
Histidine (H) Tyrosine (Y)
Isoleucine (I) Valine (V)
% Number of Residues in Helices % Number of Residues in Strands % Number of Residues in Coils
Contributes to the nuclear transport of the viral transcriptional activator VP16 homolog during the early phase of infection. Therefore, participates indirectly in the regulation of the immediate-early gene expression. Additionally, seems to be important for efficient nuclear targeting of capsids (By similarity).
Not Available
Virion tegument . Host cytoplasm . Host nucleus .
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Predicted/Modelled
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Protein couldn't be modeled using I-Tasser and Raptor X because of length constraints of the software.
Not Available
Virtual screening has been performed using RASPD
  • Million Molecules

Best 20 Hit molecules

    Not Available